Reactome | UQCRQ [mitochondrial inner membrane]

UQCRQ [mitochondrial inner membrane]

Stable Identifier

R-HSA-164283

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Ubiquinol-cytochrome c reductase complex 9.5 kDa protein, Complex III subunit VII

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O14949 UQCRQ

Gene Names

UQCRQ

Chain

initiator methionine:, chain:2-82

Reference Genes

BioGPS Gene:27089 UQCRQ

COSMIC (genes):UQCRQ UQCRQ

CTD Gene:27089 UQCRQ

dbSNP Gene:27089 UQCRQ

ENSEMBL:ENSG00000164405 UQCRQ

HGNC:29594 UQCRQ

KEGG:hsa:27089 UQCRQ

Monarch:27089 UQCRQ

NCBI Gene:27089 UQCRQ

OMIM:612080 UQCRQ

UCSC:O14949 UQCRQ

Reference Transcript

RefSeq:NM_014402.4 UQCRQ

Other Identifiers

11733901_a_at

11733902_a_at

11760191_at

16989130

201568_PM_at

201568_at

27089

2828788

2828789

2828790

2828791

2828792

2828793

2828794

2828795

34400_at

8107998

A_14_P103354

A_14_P200146

A_23_P213718

GE61178

GO:0005739

GO:0005743

GO:0005750

GO:0006091

GO:0006122

GO:0021539

GO:0021548

GO:0021680

GO:0021766

GO:0021794

GO:0021854

GO:0021860

GO:0030901

GO:0043226

GO:0045275

GO:0045333

GO:0048856

HMNXSV003000105

ILMN_1666471

PH_hs_0022620

TC05000646.hg

g7657485_3p_at

Participates

as a member of

Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)

as an input of

Intermediate I binds second heme, UQCRB, UQCRQ (Homo sapiens)

as a component of

Inferred To

QCR8 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

UQCRQ [mitochondrial inner membrane] (Bos taurus)

UQCRQ [mitochondrial inner membrane] (Caenorhabditis elegans)

UQCRQ [mitochondrial inner membrane] (Canis familiaris)

UQCRQ [mitochondrial inner membrane] (Dictyostelium discoideum)

UQCRQ [mitochondrial inner membrane] (Gallus gallus)

UQCRQ [mitochondrial inner membrane] (Sus scrofa)

Uqcrq [mitochondrial inner membrane] (Mus musculus)

Uqcrq [mitochondrial inner membrane] (Rattus norvegicus)

qcr8 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

UQCR-Q [mitochondrial inner membrane] (Drosophila melanogaster)

uqcrq [mitochondrial inner membrane] (Danio rerio)

Cross References

ENSEMBL

ENSP00000367936, ENSP00000367934, ENSP00000367939, ENST00000378670, ENSG00000164405, ENST00000378667, ENST00000378665

OpenTargets

ENSG00000164405

GeneCards

UQCRQ

HPA

ENSG00000164405-UQCRQ

PRO

O14949

Pharos - Targets

O14949

GlyGen

O14949

Orphanet

UQCRQ

HMDB Protein

HMDBP02273

PDB

5XTE, 5XTI, 5XTH

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31930 UQCRC1	1	UQCRC1 [mitochondrial inner membrane] (R-HSA-164284)	0.669	4
UniProt:P14854 COX6B1	1	COX6B1 [mitochondrial inner membrane] (R-HSA-164299)	0.527	2
UniProt:Q9H7Z7 PTGES2	3	PTGES2(88-377) [cytosol] (R-HSA-5423596) PTGES2 [extracellular region] (R-HSA-6806185) PTGES2 [azurophil granule lumen] (R-HSA-6799232)	0.527	3
UniProt:P01037 CYTN			0.527	2
UniProt:Q8TCT7 SPPL2B	1	SPPL2B [plasma membrane] (R-HSA-8863116)	0.527	3
UniProt:Q96DR5 BPIFA2	1	BPIFA2 [extracellular region] (R-HSA-6809279)	0.527	2
UniProt:P01036 CYTS			0.527	2
UniProt:P00156 MT-CYB	1	MT-CYB [mitochondrial inner membrane] (R-HSA-164281)	0.527	2
UniProt:P07919 UQCRH	1	UQCRH [mitochondrial inner membrane] (R-HSA-164286)	0.527	2
UniProt:O14548 COX7A2L	1	COX7A2L [mitochondrial inner membrane] (R-HSA-164310)	0.527	2
UniProt:P01877 IGHA2	1	IGHA2 [extracellular region] (R-HSA-1478812)	0.527	2
UniProt:P22695 UQCRC2	1	UQCRC2 [mitochondrial inner membrane] (R-HSA-164280)	0.527	2
UniProt:P14927 UQCRB	1	UQCRB [mitochondrial inner membrane] (R-HSA-164287)	0.527	3