Reactome | COX4I1 [mitochondrial inner membrane]

COX4I1 [mitochondrial inner membrane]

Stable Identifier

R-HSA-164305

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Cytochrome c oxidase subunit IV isoform 1, COX IV-1, Cytochrome c oxidase polypeptide IV

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P13073 COX4I1

Gene Names

COX4I1, COX4

Chain

transit peptide:1-22, chain:23-169

Reference Genes

BioGPS Gene:1327 COX4I1

COSMIC (genes):COX4I1 COX4I1

CTD Gene:1327 COX4I1

dbSNP Gene:1327 COX4I1

ENSEMBL:ENSG00000131143 COX4I1

ENSEMBL:ENSG00000131143.10 COX4I1

HGNC:2265 COX4I1

KEGG Gene (Homo sapiens):1327 COX4I1

Monarch:1327 COX4I1

NCBI Gene:1327 COX4I1

OMIM:123864 COX4I1

UCSC:P13073 COX4I1

Reference Transcript

Other Identifiers

11715377_x_at

1327

16821614

18671084

18671085

18671086

18671087

18671088

18671089

200086_PM_s_at

200086_s_at

202698_PM_x_at

202698_x_at

3672461

3672462

3672463

3672466

3672469

3672472

3672473

3672474

39027_at

7997702

GO:0003824

GO:0004129

GO:0005215

GO:0005515

GO:0005634

GO:0005654

GO:0005739

GO:0005743

GO:0005751

GO:0005829

GO:0006091

GO:0006119

GO:0006123

GO:0016020

GO:0016491

GO:0031966

GO:0043226

GO:0045333

GO:0055085

GO:1902600

HMNXSV003055492

Hs.113205.1.S1_3p_s_at

ILMN_1652207

PH_hs_0020120

TC16000665.hg

U90915_at

Participates

as a component of

Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)

Inferred To

COX4 [mitochondrial inner membrane] (Drosophila melanogaster)

COX4I1 [mitochondrial inner membrane] (Bos taurus)

COX4I1 [mitochondrial inner membrane] (Canis familiaris)

COX4I1 [mitochondrial inner membrane] (Danio rerio)

COX4I1 [mitochondrial inner membrane] (Gallus gallus)

COX4I1 [mitochondrial inner membrane] (Sus scrofa)

cox4i1 [mitochondrial inner membrane] (Xenopus tropicalis)

Cox4i1 [mitochondrial inner membrane] (Mus musculus)

Cox4i1 [mitochondrial inner membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001305723.1, NP_001852.1, NP_001305717.1, NP_001305715.1, NP_001305731.1, NP_001305726.1

OpenTargets

ENSG00000131143

GeneCards

P13073

HPA

ENSG00000131143-COX4I1

Ensembl

ENSP00000457513, ENSP00000457015, ENSG00000131143, ENST00000561569, ENSP00000253452, ENST00000562336, ENST00000253452

PRO

P13073

Pharos - Targets

P13073

Orphanet

26010

PDB

5Z62

HMDB Protein

HMDBP03204

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O00560 SDCBP	3	SDCBP [extracellular region] (R-HSA-6806206) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [cytosol] (R-HSA-373639)	0.666	4
UniProt:P10809 HSPD1	6	HSPD1(1-573) [cytosol] (R-HSA-1267989) HSPD1(1-573) [mitochondrial intermembrane space] (R-HSA-1267963) HSPD1(1-26) [mitochondrial matrix] (R-HSA-8986171) HSPD1(1-573) [mitochondrial inner membrane] (R-HSA-1299442) HSPD1 [mitochondrial inner membrane] (R-HSA-1299455) HSPD1 [mitochondrial matrix] (R-HSA-1299448)	0.483	2
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.483	2
UniProt:P04578 env	7	Surface protein gp120 (P04578) [cytosol] (R-HIV-189269) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211)	0.462	2