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COMMD10 [nucleoplasm]
Stable Identifier
R-HSA-8955101
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
COMM domain-containing protein 10, COMDA_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Neddylation (Homo sapiens)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Homo sapiens)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD10 [nucleoplasm] (Homo sapiens)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD10 [nucleoplasm] (Homo sapiens)
COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD10 [nucleoplasm] (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD10 [nucleoplasm] (Homo sapiens)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD10 [nucleoplasm] (Homo sapiens)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD10 [nucleoplasm] (Homo sapiens)
NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD10 [nucleoplasm] (Homo sapiens)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD10 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y6G5 COMMD10
Gene Names
COMMD10, HSPC305, PTD002
Chain
initiator methionine:, chain:2-202
Reference Genes
BioGPS Gene:51397 COMMD10
COSMIC (genes):COMMD10 COMMD10
CTD Gene:51397 COMMD10
dbSNP Gene:51397 COMMD10
ENSEMBL:ENSG00000145781 COMMD10
ENSEMBL_homo_sapiens_GENE:ENSG00000145781.9 COMMD10
HGNC:30201 COMMD10
KEGG Gene (Homo sapiens):51397 COMMD10
Monarch:51397 COMMD10
NCBI Gene:51397 COMMD10
OMIM:616704 COMMD10
UCSC:Q9Y6G5 COMMD10
Reference Transcript
RefSeq:NM_016144.3 COMMD10
RefSeq:NM_001308080.1 COMMD10
Other Identifiers
11743059_at
11743060_s_at
11759427_x_at
16988232
218439_PM_s_at
218439_s_at
222637_PM_at
222637_at
2824990
2824991
2824994
2824996
2824997
2825000
2825029
2825030
2825031
2825032
2825041
51397
52027_at
8107458
A_14_P201880
A_23_P252403
A_24_P20767
GE56030
GE82083
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0043226
HMNXSV003001882
ILMN_2094905
PH_hs_0022686
TC05000551.hg
g13528749_3p_at
g7706662_3p_a_at
Participates
as a candidate of
COMMDs [nucleoplasm] (Homo sapiens)
Other forms of this molecule
COMMD10 [cytosol]
Inferred To
commd10 [nucleoplasm]
(Dictyostelium discoideum)
Vlet [nucleoplasm]
(Drosophila melanogaster)
Commd10 [nucleoplasm]
(Mus musculus)
Commd10 [nucleoplasm]
(Rattus norvegicus)
COMMD10 [nucleoplasm]
(Bos taurus)
COMMD10 [nucleoplasm]
(Canis familiaris)
COMMD10 [nucleoplasm]
(Gallus gallus)
COMMD10 [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
NP_001295009.1
,
NP_057228.1
OpenTargets
ENSG00000145781
GeneCards
Q9Y6G5
HPA
ENSG00000145781-COMMD10
Ensembl
ENSP00000274458
,
ENSG00000145781
,
ENST00000274458
PRO
Q9Y6G5
Pharos - Targets
Q9Y6G5
PDB
8F2U
,
8ESD
,
8F2R
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P01100 FOS
2
FOS [nucleoplasm]
(R-HSA-450216)
p-T325,T331,S362,S374-FOS [nucleoplasm]
(R-HSA-450283)
0.556
3
UniProt:P31930 UQCRC1
1
UQCRC1 [mitochondrial inner membrane]
(R-HSA-164284)
0.556
3
UniProt:Q53FT3 HIKESHI
2
Hikeshi [cytosol]
(R-HSA-5216031)
Hikeshi [nucleoplasm]
(R-HSA-5252048)
0.527
2
UniProt:Q96S44 TP53RK
1
TP53RK [nucleoplasm]
(R-HSA-6784489)
0.527
2
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