Reactome | UQCRB [mitochondrial inner membrane]

UQCRB [mitochondrial inner membrane]

Stable Identifier

R-HSA-164287

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Ubiquinol-cytochrome c reductase complex 14 kDa protein, Complex III subunit VI

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P14927 UQCRB

Gene Names

UQCRB, UQBP

Chain

initiator methionine:, chain:2-111

Reference Genes

BioGPS Gene:7381 UQCRB

COSMIC (genes):UQCRB UQCRB

CTD Gene:7381 UQCRB

dbSNP Gene:7381 UQCRB

ENSEMBL:ENSG00000156467 UQCRB

ENSEMBL_homo_sapiens_GENE:ENSG00000156467.10 UQCRB

HGNC:12582 UQCRB

KEGG Gene (Homo sapiens):7381 UQCRB

Monarch:7381 UQCRB

NCBI Gene:7381 UQCRB

OMIM:191330 UQCRB

UCSC:P14927 UQCRB

Reference Transcript

Other Identifiers

11716469_x_at

11716470_at

11751680_a_at

11762275_x_at

205849_PM_s_at

205849_s_at

209065_PM_at

209065_at

209066_PM_x_at

209066_x_at

244293_PM_at

244293_at

3145559

3145561

3145563

3145565

3145566

3145568

3145569

3145570

3145572

3145576

3145578

3145582

39427_at

4010095

50062_at

7381

84064_at

A_23_P31671

A_33_P3299882

GE57868

GO:0005515

GO:0005739

GO:0005743

GO:0005746

GO:0005750

GO:0006091

GO:0006119

GO:0006122

GO:0009060

GO:0016020

GO:0043226

GO:0045333

GO:0070469

HMNXSV003017470

HMNXSV003031441

Hs.134946.0.A1_3p_at

ILMN_2128489

M22348_s_at

M26730_s_at

PH_hs_0007771

PH_hs_0038425

g13528857_3p_at

g190803_3p_a_at

Participates

as a component of

Ubiquinol-cytochrome c reductase [mitochondrial inner membrane] (Homo sapiens)

Inferred To

QCR7 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

UQCRB [mitochondrial inner membrane] (Bos taurus)

UQCRB [mitochondrial inner membrane] (Caenorhabditis elegans)

UQCRB [mitochondrial inner membrane] (Dictyostelium discoideum)

UQCRB [mitochondrial inner membrane] (Gallus gallus)

UQCRB [mitochondrial inner membrane] (Sus scrofa)

Uqcrb [mitochondrial inner membrane] (Mus musculus)

Uqcrb [mitochondrial inner membrane] (Rattus norvegicus)

UQCR-14 [mitochondrial inner membrane] (Drosophila melanogaster)

im:6900881 [mitochondrial inner membrane] (Danio rerio)

qcr7 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_006285.1, NP_001186904.1, NP_001241681.1

OpenTargets

ENSG00000156467

ZINC - Substances

QCR7_HUMAN

ZINC target

P14927

PRO

P14927

PDB

5XTH, 5XTE, 5XTI

HPA

ENSG00000156467-UQCRB

GeneCards

P14927

Ensembl

ENST00000287022, ENSP00000287022, ENST00000518406, ENSP00000430494, ENSG00000156467

Pharos - Targets

P14927

ZINC - Predictions - Purchasable

QCR7_HUMAN

Orphanet

17669

HMDB Protein

HMDBP00988

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BRX5 GINS3	1	GINS3 [nucleoplasm] (R-HSA-5688046)	0.556	3
UniProt:Q13352 ITGB3BP	2	ITGB3BP [cytosol] (R-HSA-3006405) ITGB3BP [nucleoplasm] (R-HSA-606325)	0.556	3
UniProt:Q14457 BECN1	4	K63polyUb-BECN1 [cytosol] (R-HSA-6782989) ISG15-K-BECN1 [cytosol] (R-HSA-9853030) p-S15-BECN1 [cytosol] (R-HSA-5682391) BECN1 [cytosol] (R-HSA-1632841)	0.556	3