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STOM [plasma membrane]
Stable Identifier
R-HSA-6806258
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Erythrocyte band 7 integral membrane protein, STOM_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule membrane proteins (Homo sapiens)
Azurophil granule membrane proteins [plasma membrane] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
Exocytosis of tertiary granule membrane proteins (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 binds effectors at the plasma membrane (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
CDC42:GTP:CDC42 effectors [plasma membrane] (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA binds effectors at the plasma membrane (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB binds effectors at the plasma membrane (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC binds effectors at the plasma membrane (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
RHOC:GTP:RHOC effectors [plasma membrane] (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
RHOH GTPase cycle (Homo sapiens)
RHOH binds effectors at the plasma membrane (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
RHOH:GTP:RHOH effectors [plasma membrane] (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
RHOJ GTPase cycle (Homo sapiens)
RHOJ binds effectors at the plasma membrane (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
RHOJ:GTP:RHOJ effectors [plasma membrane] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
RHOQ GTPase cycle (Homo sapiens)
RHOQ binds effectors at the plasma membrane (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
ASICs bind STOML3, (STOM) (Homo sapiens)
ASIC trimers:H+:STOML3,(STOM) [plasma membrane] (Homo sapiens)
STOML3, (STOM) [plasma membrane] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
STOML3, (STOM) [plasma membrane] (Homo sapiens)
STOM [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P27105 STOM
Gene Names
STOM, BND7, EPB72
Chain
chain:1-288
Reference Genes
BioGPS Gene:2040 STOM
COSMIC (genes):STOM STOM
CTD Gene:2040 STOM
dbSNP Gene:2040 STOM
ENSEMBL:ENSG00000148175 STOM
ENSEMBL_homo_sapiens_GENE:ENSG00000148175.13 STOM
HGNC:3383 STOM
KEGG Gene (Homo sapiens):2040 STOM
Monarch:2040 STOM
NCBI Gene:2040 STOM
OMIM:133090 STOM
UCSC:P27105 STOM
Reference Transcript
RefSeq:NM_198194.2 STOM
RefSeq:NM_004099.5 STOM
Other Identifiers
11715792_a_at
11720603_a_at
11720604_x_at
11749061_x_at
11749252_a_at
17098027
201060_PM_x_at
201060_x_at
201061_PM_s_at
201061_s_at
2040
3223929
3223930
3223931
3223932
3223933
3223934
3223938
3223940
3223942
3223943
3223946
3223947
3223957
3223958
40419_at
8163896
A_23_P255263
A_24_P141214
GE62912
GE86655
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005739
GO:0005764
GO:0005773
GO:0005783
GO:0005856
GO:0005886
GO:0006886
GO:0008200
GO:0016020
GO:0031410
GO:0031982
GO:0034765
GO:0035577
GO:0035579
GO:0042470
GO:0042802
GO:0042803
GO:0043226
GO:0044829
GO:0045121
GO:0048471
GO:0048524
GO:0055085
GO:0070062
GO:0070063
GO:0070821
GO:0072562
GO:0090314
GO:0098772
HMNXSV003017121
Hs.160483.0.S2_3p_a_at
ILMN_1696419
ILMN_1766657
PH_hs_0033446
TC09001547.hg
X85116_rna1_s_at
g181183_3p_a_at
Participates
as a candidate of
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
STOML3, (STOM) [plasma membrane] (Homo sapiens)
as a member of
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
Azurophil granule membrane proteins [plasma membrane] (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
STOM [tertiary granule membrane]
STOM [azurophil granule membrane]
STOM [specific granule membrane]
Inferred To
Homologues of STOM [plasma membrane]
(Danio rerio)
Homologues of STOM [plasma membrane]
(Dictyostelium discoideum)
sto-2 [plasma membrane]
(Caenorhabditis elegans)
stoml3b [plasma membrane]
(Danio rerio)
Stom [plasma membrane]
(Mus musculus)
Stom [plasma membrane]
(Rattus norvegicus)
STOM [plasma membrane]
(Bos taurus)
STOM [plasma membrane]
(Canis familiaris)
STOM [plasma membrane]
(Dictyostelium discoideum)
STOM [plasma membrane]
(Drosophila melanogaster)
STOM [plasma membrane]
(Gallus gallus)
STOM [plasma membrane]
(Sus scrofa)
stom [plasma membrane]
(Xenopus tropicalis)
stoml3a [plasma membrane]
(Danio rerio)
Cross References
RefSeq
NP_937837.1
,
NP_004090.4
OpenTargets
ENSG00000148175
HPA
ENSG00000148175-STOM
GeneCards
P27105
Ensembl
ENSP00000339607
,
ENSG00000148175
,
ENST00000347359
,
ENST00000286713
,
ENSP00000286713
PRO
P27105
Pharos - Targets
P27105
PDB
7WH3
Interactors (34)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q969S0 SLC35B4
1
SLC35B4 [Golgi membrane]
(R-HSA-742365)
0.556
3
UniProt:P06681 C2
3
C2b [extracellular region]
(R-HSA-166781)
C2 [extracellular region]
(R-HSA-166778)
C2a [extracellular region]
(R-HSA-166780)
0.556
3
UniProt:P01375 TNF
5
TNF(52-76) [extracellular region]
(R-HSA-8863375)
TNF(1-34) [plasma membrane]
(R-HSA-8863367)
TNF(1-76) [plasma membrane]
(R-HSA-8863120)
TNF(77-233) [extracellular region]
(R-HSA-976821)
TNF(1-233) [plasma membrane]
(R-HSA-66220)
0.556
3
UniProt:Q8N661 TMEM86B
1
TMEM86B [endoplasmic reticulum membrane]
(R-HSA-8874443)
0.556
3
UniProt:O43916 CHST1
1
CHST1 [Golgi membrane]
(R-HSA-1971540)
0.556
3
UniProt:O43169 CYB5B
2
CYB5B [endoplasmic reticulum membrane]
(R-HSA-9842695)
CYB5B [mitochondrial outer membrane]
(R-HSA-8943390)
0.556
3
UniProt:O75379 VAMP4
4
VAMP4 [transport vesicle]
(R-HSA-6811023)
VAMP4 [trans-Golgi network membrane]
(R-HSA-6811021)
VAMP4 [plasma membrane]
(R-HSA-8864461)
VAMP4 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869133)
0.556
3
UniProt:P50281 MMP14
4
MMP14 [Golgi membrane]
(R-HSA-9858808)
MMP14(21-582) [Golgi lumen]
(R-HSA-1604689)
MMP14 [Golgi lumen]
(R-HSA-1604724)
MMP14 [plasma membrane]
(R-HSA-1442472)
0.556
3
UniProt:Q01453 PMP22
1
PMP22 [plasma membrane]
(R-HSA-9615623)
0.556
3
UniProt:Q99437 ATP6V0B
3
ATP6V0B [endosome membrane]
(R-HSA-912584)
ATP6V0B [phagocytic vesicle membrane]
(R-HSA-1222695)
ATP6V0B [lysosomal membrane]
(R-HSA-9640187)
0.556
3
UniProt:Q12981 BNIP1
1
BNIP1 [endoplasmic reticulum membrane]
(R-HSA-6810950)
0.556
3
UniProt:P27449 ATP6V0C
7
ATP6V0C [endosome membrane]
(R-HSA-912591)
ATP6V0C [phagocytic vesicle membrane]
(R-HSA-1222603)
ATP6V0C [tertiary granule membrane]
(R-HSA-6800991)
ATP6V0C [plasma membrane]
(R-HSA-6806254)
ATP6V0C [azurophil granule membrane]
(R-HSA-6799363)
ATP6V0C [ficolin-1-rich granule membrane]
(R-HSA-6800908)
ATP6V0C [lysosomal membrane]
(R-HSA-9640194)
0.556
3
UniProt:O60883 GPR37L1
1
GPR37L1 [plasma membrane]
(R-HSA-5336178)
0.556
3
UniProt:Q14508 WFDC2
1
WFDC2 [extracellular region]
(R-HSA-9830363)
0.556
3
UniProt:P02652 APOA2
6
APOA2(24-100) [cytosol]
(R-HSA-2395772)
APOA2(24-100) [early endosome]
(R-HSA-2569092)
APOA2(24-100) [endoplasmic reticulum lumen]
(R-HSA-174689)
APOA2(24-100) [extracellular region]
(R-HSA-174775)
p-APOA2 [endoplasmic reticulum lumen]
(R-HSA-8957014)
APOA2 [endoplasmic reticulum lumen]
(R-HSA-8956780)
0.556
3
UniProt:Q5QGT7 RTP2
2
RTP2 [endoplasmic reticulum membrane]
(R-HSA-9752982)
RTP2 [plasma membrane]
(R-HSA-8939446)
0.556
3
UniProt:O43752 STX6
2
STX6 [trans-Golgi network membrane]
(R-HSA-6811007)
STX6 [Golgi membrane]
(R-HSA-6811004)
0.556
3
UniProt:O00767 SCD
1
SCD [endoplasmic reticulum membrane]
(R-HSA-400117)
0.556
3
UniProt:P0DTC5 M
10
M [plasma membrane]
(R-COV-9755780)
N-glycan M [virion membrane]
(R-COV-9694385)
M [virion membrane]
(R-COV-9694320)
M [endocytic vesicle membrane]
(R-COV-9694563)
N-glycan M [endocytic vesicle membrane]
(R-COV-9694738)
M [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694439)
N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694446)
M [endoplasmic reticulum membrane]
(R-COV-9767620)
nascent M [endoplasmic reticulum lumen]
(R-COV-9694279)
N-glycan M [endoplasmic reticulum membrane]
(R-COV-9694684)
0.527
2
UniProt:P22695 UQCRC2
1
UQCRC2 [mitochondrial inner membrane]
(R-HSA-164280)
0.508
2
UniProt:Q9BVG9 PTDSS2
1
PTDSS2 [endoplasmic reticulum membrane]
(R-HSA-1498817)
0.508
2
UniProt:O15397 IPO8
2
IPO8 [cytosol]
(R-HSA-5578740)
IPO8 [nucleoplasm]
(R-HSA-5578747)
0.508
2
UniProt:Q99720 SIGMAR1
1
SIGMAR1 [cytosol]
(R-HSA-9679757)
0.508
2
UniProt:P48651 PTDSS1
1
PTDSS1 [endoplasmic reticulum membrane]
(R-HSA-1498806)
0.508
2
UniProt:Q92973 TNPO1
2
TNPO1 [cilium]
(R-HSA-5624896)
TNPO1 [cytosol]
(R-HSA-180743)
0.508
2
UniProt:Q96AA3 RFT1
2
RFT1 R67C [endoplasmic reticulum membrane]
(R-HSA-4570578)
RFT1 [endoplasmic reticulum membrane]
(R-HSA-449255)
0.508
2
UniProt:Q96N66 MBOAT7
1
MBOAT7 [endoplasmic reticulum membrane]
(R-HSA-1498778)
0.508
2
UniProt:Q14974 KPNB1
5
KPNB1 [specific granule lumen]
(R-HSA-6799646)
KPNB1 [extracellular region]
(R-HSA-6806306)
KPNB1 [ficolin-1-rich granule lumen]
(R-HSA-6800978)
KPNB1 [nucleoplasm]
(R-HSA-180714)
KPNB1 [cytosol]
(R-HSA-180733)
0.508
2
UniProt:Q8TCT9 HM13
1
HM13 [endoplasmic reticulum membrane]
(R-HSA-9708544)
0.508
2
UniProt:P21796 VDAC1
7
PolyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-6783079)
VDAC1 [mitochondrial intermembrane space]
(R-HSA-1267960)
VDAC1 [mitochondrial outer membrane]
(R-HSA-1267988)
Ub-VDAC1 [mitochondrial outer membrane]
(R-HSA-9834989)
K48polyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-5205624)
K63polyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-9834037)
p-S65-Ub:VDAC1 [mitochondrial outer membrane]
(R-HSA-9834991)
0.508
2
UniProt:P63000 RAC1
6
RAC1 [ficolin-1-rich granule membrane]
(R-HSA-6804802)
RAC1 [secretory granule membrane]
(R-HSA-6804770)
GGC-PalmC-RAC1 [plasma membrane]
(R-HSA-2316446)
RAC1 [endoplasmic reticulum membrane]
(R-HSA-5672076)
RAC1 [cytosol]
(R-HSA-442615)
RAC1 [plasma membrane]
(R-HSA-351141)
0.508
2
UniProt:Q15125 EBP
1
EBP [endoplasmic reticulum membrane]
(R-HSA-195697)
0.508
2
UniProt:P31930 UQCRC1
1
UQCRC1 [mitochondrial inner membrane]
(R-HSA-164284)
0.508
2
UniProt:P35232 PHB
2
PHB [cytosol]
(R-HSA-5672944)
PHB [mitochondrial inner membrane]
(R-HSA-8953720)
0.508
2
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