thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+

Stable Identifier
R-HSA-73646
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
regeneration of active (reduced) Thioredoxin
ReviewStatus
5/5
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Cytosolic thioredoxin reductase catalyzes the reaction of thioredoxin, oxidized and NADPH + H+ to form thioredoxin, reduced and NADP+ (Urig et al. 2006).
Literature References
PubMed ID Title Journal Year
16750198 Truncated mutants of human thioredoxin reductase 1 do not exhibit glutathione reductase activity

Lieske, J, Urig, S, Irmler, A, Fritz-Wolf, K, Becker, K

FEBS Lett 2006
Participants
Participates
Catalyst Activity

thioredoxin-disulfide reductase activity of TNXRD1:FAD dimer [cytosol]

Orthologous Events
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