Reactome | FST [extracellular region]

FST [extracellular region]

Stable Identifier

R-HSA-2473211

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Follistatin, FST_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P19883 FST

Gene Names

FST

Chain

signal peptide:1-29, chain:30-344

Reference Genes

BioGPS Gene:10468 FST

COSMIC (genes):FST FST

CTD Gene:10468 FST

dbSNP Gene:10468 FST

ENSEMBL:ENSG00000134363 FST

ENSEMBL_homo_sapiens_GENE:ENSG00000134363.12 FST

HGNC:3971 FST

KEGG Gene (Homo sapiens):10468 FST

Monarch:10468 FST

NCBI Gene:10468 FST

OMIM:136470 FST

UCSC:P19883 FST

Reference Transcript

Other Identifiers

10468

11724032_a_at

11732712_a_at

11732713_at

16984730

204948_PM_s_at

204948_s_at

207345_PM_at

207345_at

226847_PM_at

226847_at

2809400

2809401

2809403

2809405

2809406

2809409

2809410

2809411

2809412

2809413

38356_at

63032_at

8105302

A_23_P110531

GE62005

GE80818

GO:0000122

GO:0001501

GO:0002244

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0006351

GO:0006355

GO:0007276

GO:0007389

GO:0008585

GO:0014070

GO:0022414

GO:0023052

GO:0030154

GO:0030509

GO:0030510

GO:0030857

GO:0031069

GO:0032926

GO:0036305

GO:0038102

GO:0042475

GO:0043226

GO:0043395

GO:0043616

GO:0048185

GO:0048856

GO:0051798

GO:0071363

GO:0098772

HMNXSV003018765

HMNXSV003038709

Hs.301570.0.S1_3p_at

ILMN_1700081

ILMN_1712896

ILMN_1878026

M19481_at

PH_hs_0001026

TC05000220.hg

g7242221_3p_s_at

g7242223_3p_at

Participates

as a component of

Activin A,AB,B:FST [extracellular region] (Homo sapiens)

as an input of

Follistatin (FST) binds Activin (Homo sapiens)

Inferred To

fsta [extracellular region] (Danio rerio)

Fs [extracellular region] (Drosophila melanogaster)

fst [extracellular region] (Xenopus tropicalis)

Fst [extracellular region] (Mus musculus)

Fst [extracellular region] (Rattus norvegicus)

Homologues of FST [extracellular region] (Sus scrofa)

FST [extracellular region] (Bos taurus)

FST [extracellular region] (Canis familiaris)

FST [extracellular region] (Gallus gallus)

FST [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_006341.1, NP_037541.1

OpenTargets

ENSG00000134363

GeneCards

P19883

HPA

ENSG00000134363-FST

Ensembl

ENST00000396947, ENSG00000134363, ENSP00000256759, ENSP00000380151, ENST00000256759

PRO

P19883

Pharos - Targets

P19883

PDB

2B0U, 2P6A, 5JHW, 3HH2

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P03950 ANG	2	ANG [cytosol] (R-HSA-9708345) ANG [extracellular region] (R-HSA-5692435)	0.571	3
UniProt:Q96SQ5 ZNF587	1	ZNF587 [nucleoplasm] (R-HSA-2127565)	0.556	3
UniProt:Q9BXY8 BEX2			0.556	3
UniProt:Q8TAU3 ZNF417	1	ZNF417 [nucleoplasm] (R-HSA-1247539)	0.556	3
UniProt:Q02930-3 CREB5			0.556	5
UniProt:Q8NEC5 CATSPER1	1	CATSPER1 [plasma membrane] (R-HSA-2534335)	0.556	3
UniProt:P10599 TXN	4	2xHC-TXN [nucleoplasm] (R-HSA-9617733) TXN [nucleoplasm] (R-HSA-9617732) 2xHC-TXN [cytosol] (R-HSA-73668) TXN [cytosol] (R-HSA-66000)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:Q14689 DIP2A			0.544	2