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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
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Cytomics
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NADP+ [mitochondrial matrix]
Stable Identifier
R-ALL-113563
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
NADP, NADP(+), Nicotinamide adenine dinucleotide phosphate, beta-Nicotinamide adenine dinucleotide phosphate, TPN, Triphosphopyridine nucleotide
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to chemical stress (Bos taurus)
Detoxification of Reactive Oxygen Species (Bos taurus)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Bos taurus)
NADP+ [mitochondrial matrix]
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Bos taurus)
NADP+ [mitochondrial matrix]
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Citric acid cycle (TCA cycle) (Bos taurus)
IDH2 dimer decarboxylates isocitrate (Bos taurus)
NADP+ [mitochondrial matrix]
NNT dimer transfers proton from NADPH to NAD+ (Bos taurus)
NADP+ [mitochondrial matrix]
Pyruvate metabolism (Bos taurus)
ME3 tetramer decarboxylates MAL to PYR (Bos taurus)
NADP+ [mitochondrial matrix]
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Cytochrome P450 - arranged by substrate type (Bos taurus)
Endogenous sterols (Bos taurus)
CYP11A1 cleaves 20a,22b-DHCHOL (Bos taurus)
NADP+ [mitochondrial matrix]
CYP11B1 oxidises 11DCORT (Bos taurus)
NADP+ [mitochondrial matrix]
CYP11B2 18-hydroxylates CORST to 18HCORST (Bos taurus)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Bos taurus)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Bos taurus)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates CHOL (Bos taurus)
NADP+ [mitochondrial matrix]
Vitamins (Bos taurus)
CYP24A1 24-hydroxylates CTL (Bos taurus)
NADP+ [mitochondrial matrix]
Metabolism of amino acids and derivatives (Bos taurus)
Glutamate and glutamine metabolism (Bos taurus)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Bos taurus)
NADP+ [mitochondrial matrix]
Lysine catabolism (Bos taurus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Bos taurus)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Fatty acyl-CoA biosynthesis (Bos taurus)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Bos taurus)
NADP+ [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Bos taurus)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Bos taurus)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Bos taurus)
MECR dimer reduces tdec2-CoA to DEC-CoA (Bos taurus)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Bos taurus)
Bile acid and bile salt metabolism (Bos taurus)
Synthesis of bile acids and bile salts (Bos taurus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Bos taurus)
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Bos taurus)
NADP+ [mitochondrial matrix]
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Bos taurus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Bos taurus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Bos taurus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Bos taurus)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Bos taurus)
NADP+ [mitochondrial matrix]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Bos taurus)
CYP27A1 27-hydroxylates CHOL (Bos taurus)
NADP+ [mitochondrial matrix]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Bos taurus)
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Bos taurus)
NADP+ [mitochondrial matrix]
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Bos taurus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Bos taurus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Bos taurus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Bos taurus)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Bos taurus)
NADP+ [mitochondrial matrix]
Metabolism of steroid hormones (Bos taurus)
Estrogen biosynthesis (Bos taurus)
AKR1B15 reduces EST17b to E1 (Bos taurus)
NADP+ [mitochondrial matrix]
Glucocorticoid biosynthesis (Bos taurus)
CYP11B1 oxidises 11DCORT (Bos taurus)
NADP+ [mitochondrial matrix]
Mineralocorticoid biosynthesis (Bos taurus)
CYP11B2 18-hydroxylates CORST to 18HCORST (Bos taurus)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Bos taurus)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Bos taurus)
NADP+ [mitochondrial matrix]
Pregnenolone biosynthesis (Bos taurus)
CYP11A1 cleaves 20a,22b-DHCHOL (Bos taurus)
NADP+ [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Bos taurus)
NADP+ [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Bos taurus)
NADP+ [mitochondrial matrix]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Metabolism of folate and pterines (Bos taurus)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Bos taurus)
NADP+ [mitochondrial matrix]
Nicotinate metabolism (Bos taurus)
NADK2 dimer phosphorylates NAD+ to NADP+ (Bos taurus)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Bos taurus)
Electron transport from NADPH to Ferredoxin (Bos taurus)
NADPH transfers electrons to FDXR (Bos taurus)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to chemical stress (Caenorhabditis elegans)
Detoxification of Reactive Oxygen Species (Caenorhabditis elegans)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Caenorhabditis elegans)
NADP+ [mitochondrial matrix]
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Caenorhabditis elegans)
NADP+ [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Citric acid cycle (TCA cycle) (Caenorhabditis elegans)
IDH2 dimer decarboxylates isocitrate (Caenorhabditis elegans)
NADP+ [mitochondrial matrix]
NNT dimer transfers proton from NADPH to NAD+ (Caenorhabditis elegans)
NADP+ [mitochondrial matrix]
Pyruvate metabolism (Caenorhabditis elegans)
ME3 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)
NADP+ [mitochondrial matrix]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Glutamate and glutamine metabolism (Caenorhabditis elegans)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Caenorhabditis elegans)
NADP+ [mitochondrial matrix]
Lysine catabolism (Caenorhabditis elegans)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Caenorhabditis elegans)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Mitochondrial Fatty Acid Beta-Oxidation (Caenorhabditis elegans)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Caenorhabditis elegans)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Caenorhabditis elegans)
MECR dimer reduces tdec2-CoA to DEC-CoA (Caenorhabditis elegans)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Caenorhabditis elegans)
Metabolism of steroid hormones (Caenorhabditis elegans)
Estrogen biosynthesis (Caenorhabditis elegans)
AKR1B15 reduces EST17b to E1 (Caenorhabditis elegans)
NADP+ [mitochondrial matrix]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Metabolism of folate and pterines (Caenorhabditis elegans)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Caenorhabditis elegans)
NADP+ [mitochondrial matrix]
Nicotinate metabolism (Caenorhabditis elegans)
NADK2 dimer phosphorylates NAD+ to NADP+ (Caenorhabditis elegans)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Caenorhabditis elegans)
Electron transport from NADPH to Ferredoxin (Caenorhabditis elegans)
NADPH transfers electrons to FDXR (Caenorhabditis elegans)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Detoxification of Reactive Oxygen Species (Canis familiaris)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Canis familiaris)
NADP+ [mitochondrial matrix]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Citric acid cycle (TCA cycle) (Canis familiaris)
IDH2 dimer decarboxylates isocitrate (Canis familiaris)
NADP+ [mitochondrial matrix]
NNT dimer transfers proton from NADPH to NAD+ (Canis familiaris)
NADP+ [mitochondrial matrix]
Pyruvate metabolism (Canis familiaris)
ME3 tetramer decarboxylates MAL to PYR (Canis familiaris)
NADP+ [mitochondrial matrix]
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Endogenous sterols (Canis familiaris)
CYP11A1 cleaves 20a,22b-DHCHOL (Canis familiaris)
NADP+ [mitochondrial matrix]
CYP11B1 oxidises 11DCORT (Canis familiaris)
NADP+ [mitochondrial matrix]
CYP11B2 18-hydroxylates CORST to 18HCORST (Canis familiaris)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Canis familiaris)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Canis familiaris)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates CHOL (Canis familiaris)
NADP+ [mitochondrial matrix]
Vitamins (Canis familiaris)
CYP24A1 24-hydroxylates CTL (Canis familiaris)
NADP+ [mitochondrial matrix]
Metabolism of amino acids and derivatives (Canis familiaris)
Glutamate and glutamine metabolism (Canis familiaris)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Canis familiaris)
NADP+ [mitochondrial matrix]
Lysine catabolism (Canis familiaris)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Canis familiaris)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Fatty acyl-CoA biosynthesis (Canis familiaris)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Canis familiaris)
NADP+ [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Canis familiaris)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Canis familiaris)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Canis familiaris)
MECR dimer reduces tdec2-CoA to DEC-CoA (Canis familiaris)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Canis familiaris)
Bile acid and bile salt metabolism (Canis familiaris)
Synthesis of bile acids and bile salts (Canis familiaris)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Canis familiaris)
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Canis familiaris)
NADP+ [mitochondrial matrix]
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Canis familiaris)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Canis familiaris)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Canis familiaris)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Canis familiaris)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Canis familiaris)
NADP+ [mitochondrial matrix]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Canis familiaris)
CYP27A1 27-hydroxylates CHOL (Canis familiaris)
NADP+ [mitochondrial matrix]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Canis familiaris)
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Canis familiaris)
NADP+ [mitochondrial matrix]
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Canis familiaris)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Canis familiaris)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Canis familiaris)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Canis familiaris)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Canis familiaris)
NADP+ [mitochondrial matrix]
Metabolism of steroid hormones (Canis familiaris)
Glucocorticoid biosynthesis (Canis familiaris)
CYP11B1 oxidises 11DCORT (Canis familiaris)
NADP+ [mitochondrial matrix]
Mineralocorticoid biosynthesis (Canis familiaris)
CYP11B2 18-hydroxylates CORST to 18HCORST (Canis familiaris)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Canis familiaris)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Canis familiaris)
NADP+ [mitochondrial matrix]
Pregnenolone biosynthesis (Canis familiaris)
CYP11A1 cleaves 20a,22b-DHCHOL (Canis familiaris)
NADP+ [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Canis familiaris)
NADP+ [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Canis familiaris)
NADP+ [mitochondrial matrix]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Metabolism of folate and pterines (Canis familiaris)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Canis familiaris)
NADP+ [mitochondrial matrix]
Nicotinate metabolism (Canis familiaris)
NADK2 dimer phosphorylates NAD+ to NADP+ (Canis familiaris)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Canis familiaris)
Electron transport from NADPH to Ferredoxin (Canis familiaris)
NADPH transfers electrons to FDXR (Canis familiaris)
NADP+ [mitochondrial matrix]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Citric acid cycle (TCA cycle) (Danio rerio)
IDH2 dimer decarboxylates isocitrate (Danio rerio)
NADP+ [mitochondrial matrix]
NNT dimer transfers proton from NADPH to NAD+ (Danio rerio)
NADP+ [mitochondrial matrix]
Pyruvate metabolism (Danio rerio)
ME3 tetramer decarboxylates MAL to PYR (Danio rerio)
NADP+ [mitochondrial matrix]
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
Cytochrome P450 - arranged by substrate type (Danio rerio)
Endogenous sterols (Danio rerio)
CYP11A1 cleaves 20a,22b-DHCHOL (Danio rerio)
NADP+ [mitochondrial matrix]
Vitamins (Danio rerio)
CYP24A1 24-hydroxylates CTL (Danio rerio)
NADP+ [mitochondrial matrix]
Metabolism of amino acids and derivatives (Danio rerio)
Lysine catabolism (Danio rerio)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Danio rerio)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Danio rerio)
Fatty acid metabolism (Danio rerio)
Fatty acyl-CoA biosynthesis (Danio rerio)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Danio rerio)
NADP+ [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Danio rerio)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Danio rerio)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Danio rerio)
MECR dimer reduces tdec2-CoA to DEC-CoA (Danio rerio)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Danio rerio)
Metabolism of steroid hormones (Danio rerio)
Estrogen biosynthesis (Danio rerio)
AKR1B15 reduces EST17b to E1 (Danio rerio)
NADP+ [mitochondrial matrix]
Pregnenolone biosynthesis (Danio rerio)
CYP11A1 cleaves 20a,22b-DHCHOL (Danio rerio)
NADP+ [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Danio rerio)
NADP+ [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Danio rerio)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Danio rerio)
Electron transport from NADPH to Ferredoxin (Danio rerio)
NADPH transfers electrons to FDXR (Danio rerio)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular response to chemical stress (Dictyostelium discoideum)
Detoxification of Reactive Oxygen Species (Dictyostelium discoideum)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Dictyostelium discoideum)
NADP+ [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Aerobic respiration and respiratory electron transport (Dictyostelium discoideum)
Citric acid cycle (TCA cycle) (Dictyostelium discoideum)
NNT dimer transfers proton from NADPH to NAD+ (Dictyostelium discoideum)
NADP+ [mitochondrial matrix]
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Lysine catabolism (Dictyostelium discoideum)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Dictyostelium discoideum)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Dictyostelium discoideum)
Fatty acid metabolism (Dictyostelium discoideum)
Fatty acyl-CoA biosynthesis (Dictyostelium discoideum)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Dictyostelium discoideum)
NADP+ [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Dictyostelium discoideum)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Dictyostelium discoideum)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Dictyostelium discoideum)
MECR dimer reduces tdec2-CoA to DEC-CoA (Dictyostelium discoideum)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Dictyostelium discoideum)
Metabolism of steroid hormones (Dictyostelium discoideum)
Estrogen biosynthesis (Dictyostelium discoideum)
AKR1B15 reduces EST17b to E1 (Dictyostelium discoideum)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Dictyostelium discoideum)
Electron transport from NADPH to Ferredoxin (Dictyostelium discoideum)
NADPH transfers electrons to FDXR (Dictyostelium discoideum)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to chemical stress (Drosophila melanogaster)
Detoxification of Reactive Oxygen Species (Drosophila melanogaster)
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Drosophila melanogaster)
NADP+ [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism (Drosophila melanogaster)
ME3 tetramer decarboxylates MAL to PYR (Drosophila melanogaster)
NADP+ [mitochondrial matrix]
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Glutamate and glutamine metabolism (Drosophila melanogaster)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Drosophila melanogaster)
NADP+ [mitochondrial matrix]
Lysine catabolism (Drosophila melanogaster)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Drosophila melanogaster)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Mitochondrial Fatty Acid Beta-Oxidation (Drosophila melanogaster)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Drosophila melanogaster)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Drosophila melanogaster)
MECR dimer reduces tdec2-CoA to DEC-CoA (Drosophila melanogaster)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Drosophila melanogaster)
Metabolism of steroid hormones (Drosophila melanogaster)
Estrogen biosynthesis (Drosophila melanogaster)
AKR1B15 reduces EST17b to E1 (Drosophila melanogaster)
NADP+ [mitochondrial matrix]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Metabolism of folate and pterines (Drosophila melanogaster)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Drosophila melanogaster)
NADP+ [mitochondrial matrix]
Nicotinate metabolism (Drosophila melanogaster)
NADK2 dimer phosphorylates NAD+ to NADP+ (Drosophila melanogaster)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Drosophila melanogaster)
Electron transport from NADPH to Ferredoxin (Drosophila melanogaster)
NADPH transfers electrons to FDXR (Drosophila melanogaster)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
Detoxification of Reactive Oxygen Species (Gallus gallus)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Gallus gallus)
NADP+ [mitochondrial matrix]
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Gallus gallus)
NADP+ [mitochondrial matrix]
Metabolism (Gallus gallus)
Aerobic respiration and respiratory electron transport (Gallus gallus)
Citric acid cycle (TCA cycle) (Gallus gallus)
IDH2 dimer decarboxylates isocitrate (Gallus gallus)
NADP+ [mitochondrial matrix]
NNT dimer transfers proton from NADPH to NAD+ (Gallus gallus)
NADP+ [mitochondrial matrix]
Pyruvate metabolism (Gallus gallus)
ME3 tetramer decarboxylates MAL to PYR (Gallus gallus)
NADP+ [mitochondrial matrix]
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Cytochrome P450 - arranged by substrate type (Gallus gallus)
Endogenous sterols (Gallus gallus)
CYP11A1 cleaves 20a,22b-DHCHOL (Gallus gallus)
NADP+ [mitochondrial matrix]
Metabolism of amino acids and derivatives (Gallus gallus)
Glutamate and glutamine metabolism (Gallus gallus)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Gallus gallus)
NADP+ [mitochondrial matrix]
Lysine catabolism (Gallus gallus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Gallus gallus)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Gallus gallus)
Fatty acid metabolism (Gallus gallus)
Mitochondrial Fatty Acid Beta-Oxidation (Gallus gallus)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Gallus gallus)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Gallus gallus)
MECR dimer reduces tdec2-CoA to DEC-CoA (Gallus gallus)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Gallus gallus)
Metabolism of steroid hormones (Gallus gallus)
Estrogen biosynthesis (Gallus gallus)
AKR1B15 reduces EST17b to E1 (Gallus gallus)
NADP+ [mitochondrial matrix]
Pregnenolone biosynthesis (Gallus gallus)
CYP11A1 cleaves 20a,22b-DHCHOL (Gallus gallus)
NADP+ [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Gallus gallus)
NADP+ [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Gallus gallus)
NADP+ [mitochondrial matrix]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Metabolism of folate and pterines (Gallus gallus)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Gallus gallus)
NADP+ [mitochondrial matrix]
Nicotinate metabolism (Gallus gallus)
NADK2 dimer phosphorylates NAD+ to NADP+ (Gallus gallus)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Gallus gallus)
Electron transport from NADPH to Ferredoxin (Gallus gallus)
NADPH transfers electrons to FDXR (Gallus gallus)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Detoxification of Reactive Oxygen Species (Homo sapiens)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Homo sapiens)
NADP+ [mitochondrial matrix]
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Homo sapiens)
NADP+ [mitochondrial matrix]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
IDH2 dimer decarboxylates isocitrate (Homo sapiens)
NADP+ [mitochondrial matrix]
NNT dimer transfers proton from NADPH to NAD+ (Homo sapiens)
NADP+ [mitochondrial matrix]
Pyruvate metabolism (Homo sapiens)
ME3 tetramer decarboxylates MAL to PYR (Homo sapiens)
NADP+ [mitochondrial matrix]
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Endogenous sterols (Homo sapiens)
CYP11A1 cleaves 20a,22b-DHCHOL (Homo sapiens)
NADP+ [mitochondrial matrix]
CYP11B1 oxidises 11DCORT (Homo sapiens)
NADP+ [mitochondrial matrix]
CYP11B2 18-hydroxylates CORST to 18HCORST (Homo sapiens)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Homo sapiens)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Homo sapiens)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates CHOL (Homo sapiens)
NADP+ [mitochondrial matrix]
Vitamins (Homo sapiens)
CYP24A1 24-hydroxylates CTL (Homo sapiens)
NADP+ [mitochondrial matrix]
Metabolism of amino acids and derivatives (Homo sapiens)
Glutamate and glutamine metabolism (Homo sapiens)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Homo sapiens)
NADP+ [mitochondrial matrix]
Lysine catabolism (Homo sapiens)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Homo sapiens)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Fatty acyl-CoA biosynthesis (Homo sapiens)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Homo sapiens)
NADP+ [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Homo sapiens)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Homo sapiens)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Homo sapiens)
MECR dimer reduces tdec2-CoA to DEC-CoA (Homo sapiens)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Synthesis of bile acids and bile salts (Homo sapiens)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Homo sapiens)
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Homo sapiens)
NADP+ [mitochondrial matrix]
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Homo sapiens)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Homo sapiens)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Homo sapiens)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Homo sapiens)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Homo sapiens)
NADP+ [mitochondrial matrix]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Homo sapiens)
CYP27A1 27-hydroxylates CHOL (Homo sapiens)
NADP+ [mitochondrial matrix]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Homo sapiens)
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Homo sapiens)
NADP+ [mitochondrial matrix]
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Homo sapiens)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Homo sapiens)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Homo sapiens)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Homo sapiens)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Homo sapiens)
NADP+ [mitochondrial matrix]
Metabolism of steroid hormones (Homo sapiens)
Estrogen biosynthesis (Homo sapiens)
AKR1B15 reduces EST17b to E1 (Homo sapiens)
NADP+ [mitochondrial matrix]
Glucocorticoid biosynthesis (Homo sapiens)
CYP11B1 oxidises 11DCORT (Homo sapiens)
NADP+ [mitochondrial matrix]
Mineralocorticoid biosynthesis (Homo sapiens)
CYP11B2 18-hydroxylates CORST to 18HCORST (Homo sapiens)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Homo sapiens)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Homo sapiens)
NADP+ [mitochondrial matrix]
Pregnenolone biosynthesis (Homo sapiens)
CYP11A1 cleaves 20a,22b-DHCHOL (Homo sapiens)
NADP+ [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Homo sapiens)
NADP+ [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Homo sapiens)
NADP+ [mitochondrial matrix]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of cofactors (Homo sapiens)
Ubiquinol biosynthesis (Homo sapiens)
Unknown enzyme hydroxylates DMPhOH (Homo sapiens)
NADP+ [mitochondrial matrix]
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Metabolism of folate and pterines (Homo sapiens)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Homo sapiens)
NADP+ [mitochondrial matrix]
Nicotinate metabolism (Homo sapiens)
NADK2 dimer phosphorylates NAD+ to NADP+ (Homo sapiens)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Homo sapiens)
Electron transport from NADPH to Ferredoxin (Homo sapiens)
NADPH transfers electrons to FDXR (Homo sapiens)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
Detoxification of Reactive Oxygen Species (Mus musculus)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Mus musculus)
NADP+ [mitochondrial matrix]
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Mus musculus)
NADP+ [mitochondrial matrix]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Citric acid cycle (TCA cycle) (Mus musculus)
IDH2 dimer decarboxylates isocitrate (Mus musculus)
NADP+ [mitochondrial matrix]
NNT dimer transfers proton from NADPH to NAD+ (Mus musculus)
NADP+ [mitochondrial matrix]
Pyruvate metabolism (Mus musculus)
ME3 tetramer decarboxylates MAL to PYR (Mus musculus)
NADP+ [mitochondrial matrix]
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Endogenous sterols (Mus musculus)
CYP11A1 cleaves 20a,22b-DHCHOL (Mus musculus)
NADP+ [mitochondrial matrix]
CYP11B1 oxidises 11DCORT (Mus musculus)
NADP+ [mitochondrial matrix]
CYP11B2 18-hydroxylates CORST to 18HCORST (Mus musculus)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Mus musculus)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Mus musculus)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates CHOL (Mus musculus)
NADP+ [mitochondrial matrix]
Vitamins (Mus musculus)
CYP24A1 24-hydroxylates CTL (Mus musculus)
NADP+ [mitochondrial matrix]
Metabolism of amino acids and derivatives (Mus musculus)
Glutamate and glutamine metabolism (Mus musculus)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Mus musculus)
NADP+ [mitochondrial matrix]
Lysine catabolism (Mus musculus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Mus musculus)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Mus musculus)
Fatty acid metabolism (Mus musculus)
Fatty acyl-CoA biosynthesis (Mus musculus)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Mus musculus)
NADP+ [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Mus musculus)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Mus musculus)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Mus musculus)
MECR dimer reduces tdec2-CoA to DEC-CoA (Mus musculus)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Mus musculus)
Bile acid and bile salt metabolism (Mus musculus)
Synthesis of bile acids and bile salts (Mus musculus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Mus musculus)
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Mus musculus)
NADP+ [mitochondrial matrix]
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Mus musculus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Mus musculus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Mus musculus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Mus musculus)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Mus musculus)
NADP+ [mitochondrial matrix]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Mus musculus)
CYP27A1 27-hydroxylates CHOL (Mus musculus)
NADP+ [mitochondrial matrix]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Mus musculus)
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Mus musculus)
NADP+ [mitochondrial matrix]
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Mus musculus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Mus musculus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Mus musculus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Mus musculus)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Mus musculus)
NADP+ [mitochondrial matrix]
Metabolism of steroid hormones (Mus musculus)
Estrogen biosynthesis (Mus musculus)
AKR1B15 reduces EST17b to E1 (Mus musculus)
NADP+ [mitochondrial matrix]
Glucocorticoid biosynthesis (Mus musculus)
CYP11B1 oxidises 11DCORT (Mus musculus)
NADP+ [mitochondrial matrix]
Mineralocorticoid biosynthesis (Mus musculus)
CYP11B2 18-hydroxylates CORST to 18HCORST (Mus musculus)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Mus musculus)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Mus musculus)
NADP+ [mitochondrial matrix]
Pregnenolone biosynthesis (Mus musculus)
CYP11A1 cleaves 20a,22b-DHCHOL (Mus musculus)
NADP+ [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Mus musculus)
NADP+ [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Mus musculus)
NADP+ [mitochondrial matrix]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Metabolism of folate and pterines (Mus musculus)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Mus musculus)
NADP+ [mitochondrial matrix]
Nicotinate metabolism (Mus musculus)
NADK2 dimer phosphorylates NAD+ to NADP+ (Mus musculus)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Mus musculus)
Electron transport from NADPH to Ferredoxin (Mus musculus)
NADPH transfers electrons to FDXR (Mus musculus)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Plasmodium falciparum)
Cellular responses to stress (Plasmodium falciparum)
Cellular response to chemical stress (Plasmodium falciparum)
Detoxification of Reactive Oxygen Species (Plasmodium falciparum)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Plasmodium falciparum)
NADP+ [mitochondrial matrix]
Metabolism (Plasmodium falciparum)
Aerobic respiration and respiratory electron transport (Plasmodium falciparum)
Citric acid cycle (TCA cycle) (Plasmodium falciparum)
IDH2 dimer decarboxylates isocitrate (Plasmodium falciparum)
NADP+ [mitochondrial matrix]
NNT dimer transfers proton from NADPH to NAD+ (Plasmodium falciparum)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Plasmodium falciparum)
Fatty acid metabolism (Plasmodium falciparum)
Fatty acyl-CoA biosynthesis (Plasmodium falciparum)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Plasmodium falciparum)
NADP+ [mitochondrial matrix]
Metabolism of vitamins and cofactors (Plasmodium falciparum)
Metabolism of water-soluble vitamins and cofactors (Plasmodium falciparum)
Nicotinate metabolism (Plasmodium falciparum)
NADK2 dimer phosphorylates NAD+ to NADP+ (Plasmodium falciparum)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Plasmodium falciparum)
Electron transport from NADPH to Ferredoxin (Plasmodium falciparum)
NADPH transfers electrons to FDXR (Plasmodium falciparum)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
Detoxification of Reactive Oxygen Species (Rattus norvegicus)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Rattus norvegicus)
NADP+ [mitochondrial matrix]
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Citric acid cycle (TCA cycle) (Rattus norvegicus)
IDH2 dimer decarboxylates isocitrate (Rattus norvegicus)
NADP+ [mitochondrial matrix]
NNT dimer transfers proton from NADPH to NAD+ (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Pyruvate metabolism (Rattus norvegicus)
ME3 tetramer decarboxylates MAL to PYR (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
Endogenous sterols (Rattus norvegicus)
CYP11A1 cleaves 20a,22b-DHCHOL (Rattus norvegicus)
NADP+ [mitochondrial matrix]
CYP11B1 oxidises 11DCORT (Rattus norvegicus)
NADP+ [mitochondrial matrix]
CYP11B2 18-hydroxylates CORST to 18HCORST (Rattus norvegicus)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Rattus norvegicus)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Rattus norvegicus)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates CHOL (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Vitamins (Rattus norvegicus)
CYP24A1 24-hydroxylates CTL (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Glutamate and glutamine metabolism (Rattus norvegicus)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Lysine catabolism (Rattus norvegicus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Fatty acyl-CoA biosynthesis (Rattus norvegicus)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Rattus norvegicus)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Rattus norvegicus)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Rattus norvegicus)
MECR dimer reduces tdec2-CoA to DEC-CoA (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Rattus norvegicus)
Bile acid and bile salt metabolism (Rattus norvegicus)
Synthesis of bile acids and bile salts (Rattus norvegicus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Rattus norvegicus)
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Rattus norvegicus)
NADP+ [mitochondrial matrix]
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Rattus norvegicus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Rattus norvegicus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Rattus norvegicus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Rattus norvegicus)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Rattus norvegicus)
CYP27A1 27-hydroxylates CHOL (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Rattus norvegicus)
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Rattus norvegicus)
NADP+ [mitochondrial matrix]
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Rattus norvegicus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Rattus norvegicus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Rattus norvegicus)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Rattus norvegicus)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Metabolism of steroid hormones (Rattus norvegicus)
Estrogen biosynthesis (Rattus norvegicus)
AKR1B15 reduces EST17b to E1 (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Glucocorticoid biosynthesis (Rattus norvegicus)
CYP11B1 oxidises 11DCORT (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Mineralocorticoid biosynthesis (Rattus norvegicus)
CYP11B2 18-hydroxylates CORST to 18HCORST (Rattus norvegicus)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Rattus norvegicus)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Pregnenolone biosynthesis (Rattus norvegicus)
CYP11A1 cleaves 20a,22b-DHCHOL (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Metabolism of folate and pterines (Rattus norvegicus)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Nicotinate metabolism (Rattus norvegicus)
NADK2 dimer phosphorylates NAD+ to NADP+ (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Rattus norvegicus)
Electron transport from NADPH to Ferredoxin (Rattus norvegicus)
NADPH transfers electrons to FDXR (Rattus norvegicus)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Cellular response to chemical stress (Saccharomyces cerevisiae)
Detoxification of Reactive Oxygen Species (Saccharomyces cerevisiae)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Saccharomyces cerevisiae)
NADP+ [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Glutamate and glutamine metabolism (Saccharomyces cerevisiae)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Saccharomyces cerevisiae)
NADP+ [mitochondrial matrix]
Lysine catabolism (Saccharomyces cerevisiae)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Saccharomyces cerevisiae)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Saccharomyces cerevisiae)
Fatty acid metabolism (Saccharomyces cerevisiae)
Fatty acyl-CoA biosynthesis (Saccharomyces cerevisiae)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Saccharomyces cerevisiae)
NADP+ [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Saccharomyces cerevisiae)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Saccharomyces cerevisiae)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Saccharomyces cerevisiae)
MECR dimer reduces tdec2-CoA to DEC-CoA (Saccharomyces cerevisiae)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Saccharomyces cerevisiae)
Metabolism of steroid hormones (Saccharomyces cerevisiae)
Estrogen biosynthesis (Saccharomyces cerevisiae)
AKR1B15 reduces EST17b to E1 (Saccharomyces cerevisiae)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Saccharomyces cerevisiae)
Electron transport from NADPH to Ferredoxin (Saccharomyces cerevisiae)
NADPH transfers electrons to FDXR (Saccharomyces cerevisiae)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Cellular response to chemical stress (Schizosaccharomyces pombe)
Detoxification of Reactive Oxygen Species (Schizosaccharomyces pombe)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Schizosaccharomyces pombe)
NADP+ [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Glutamate and glutamine metabolism (Schizosaccharomyces pombe)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Schizosaccharomyces pombe)
NADP+ [mitochondrial matrix]
Lysine catabolism (Schizosaccharomyces pombe)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Schizosaccharomyces pombe)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Schizosaccharomyces pombe)
Fatty acid metabolism (Schizosaccharomyces pombe)
Fatty acyl-CoA biosynthesis (Schizosaccharomyces pombe)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Schizosaccharomyces pombe)
NADP+ [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Schizosaccharomyces pombe)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Schizosaccharomyces pombe)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Schizosaccharomyces pombe)
MECR dimer reduces tdec2-CoA to DEC-CoA (Schizosaccharomyces pombe)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Schizosaccharomyces pombe)
Metabolism of steroid hormones (Schizosaccharomyces pombe)
Estrogen biosynthesis (Schizosaccharomyces pombe)
AKR1B15 reduces EST17b to E1 (Schizosaccharomyces pombe)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Schizosaccharomyces pombe)
Electron transport from NADPH to Ferredoxin (Schizosaccharomyces pombe)
NADPH transfers electrons to FDXR (Schizosaccharomyces pombe)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
Detoxification of Reactive Oxygen Species (Sus scrofa)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Sus scrofa)
NADP+ [mitochondrial matrix]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Citric acid cycle (TCA cycle) (Sus scrofa)
IDH2 dimer decarboxylates isocitrate (Sus scrofa)
NADP+ [mitochondrial matrix]
Pyruvate metabolism (Sus scrofa)
ME3 tetramer decarboxylates MAL to PYR (Sus scrofa)
NADP+ [mitochondrial matrix]
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Cytochrome P450 - arranged by substrate type (Sus scrofa)
Endogenous sterols (Sus scrofa)
CYP11A1 cleaves 20a,22b-DHCHOL (Sus scrofa)
NADP+ [mitochondrial matrix]
CYP11B1 oxidises 11DCORT (Sus scrofa)
NADP+ [mitochondrial matrix]
CYP11B2 18-hydroxylates CORST to 18HCORST (Sus scrofa)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Sus scrofa)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Sus scrofa)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates CHOL (Sus scrofa)
NADP+ [mitochondrial matrix]
Vitamins (Sus scrofa)
CYP24A1 24-hydroxylates CTL (Sus scrofa)
NADP+ [mitochondrial matrix]
Metabolism of amino acids and derivatives (Sus scrofa)
Glutamate and glutamine metabolism (Sus scrofa)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Sus scrofa)
NADP+ [mitochondrial matrix]
Lysine catabolism (Sus scrofa)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Sus scrofa)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Sus scrofa)
Fatty acid metabolism (Sus scrofa)
Fatty acyl-CoA biosynthesis (Sus scrofa)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Sus scrofa)
NADP+ [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Sus scrofa)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Sus scrofa)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Sus scrofa)
MECR dimer reduces tdec2-CoA to DEC-CoA (Sus scrofa)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Sus scrofa)
Bile acid and bile salt metabolism (Sus scrofa)
Synthesis of bile acids and bile salts (Sus scrofa)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Sus scrofa)
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Sus scrofa)
NADP+ [mitochondrial matrix]
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Sus scrofa)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Sus scrofa)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Sus scrofa)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Sus scrofa)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Sus scrofa)
NADP+ [mitochondrial matrix]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Sus scrofa)
CYP27A1 27-hydroxylates CHOL (Sus scrofa)
NADP+ [mitochondrial matrix]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Sus scrofa)
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Sus scrofa)
NADP+ [mitochondrial matrix]
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Sus scrofa)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Sus scrofa)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Sus scrofa)
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Sus scrofa)
NADP+ [mitochondrial matrix]
CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Sus scrofa)
NADP+ [mitochondrial matrix]
Metabolism of steroid hormones (Sus scrofa)
Glucocorticoid biosynthesis (Sus scrofa)
CYP11B1 oxidises 11DCORT (Sus scrofa)
NADP+ [mitochondrial matrix]
Mineralocorticoid biosynthesis (Sus scrofa)
CYP11B2 18-hydroxylates CORST to 18HCORST (Sus scrofa)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Sus scrofa)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Sus scrofa)
NADP+ [mitochondrial matrix]
Pregnenolone biosynthesis (Sus scrofa)
CYP11A1 cleaves 20a,22b-DHCHOL (Sus scrofa)
NADP+ [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Sus scrofa)
NADP+ [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Sus scrofa)
NADP+ [mitochondrial matrix]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Metabolism of folate and pterines (Sus scrofa)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Sus scrofa)
NADP+ [mitochondrial matrix]
Nicotinate metabolism (Sus scrofa)
NADK2 dimer phosphorylates NAD+ to NADP+ (Sus scrofa)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Sus scrofa)
Electron transport from NADPH to Ferredoxin (Sus scrofa)
NADPH transfers electrons to FDXR (Sus scrofa)
NADP+ [mitochondrial matrix]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to chemical stress (Xenopus tropicalis)
Detoxification of Reactive Oxygen Species (Xenopus tropicalis)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Citric acid cycle (TCA cycle) (Xenopus tropicalis)
IDH2 dimer decarboxylates isocitrate (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
NNT dimer transfers proton from NADPH to NAD+ (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Pyruvate metabolism (Xenopus tropicalis)
ME3 tetramer decarboxylates MAL to PYR (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Biological oxidations (Xenopus tropicalis)
Phase I - Functionalization of compounds (Xenopus tropicalis)
Cytochrome P450 - arranged by substrate type (Xenopus tropicalis)
Endogenous sterols (Xenopus tropicalis)
CYP11A1 cleaves 20a,22b-DHCHOL (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
CYP11B1 oxidises 11DCORT (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
CYP11B2 18-hydroxylates CORST to 18HCORST (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Glutamate and glutamine metabolism (Xenopus tropicalis)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Lysine catabolism (Xenopus tropicalis)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Metabolism of lipids (Xenopus tropicalis)
Fatty acid metabolism (Xenopus tropicalis)
Fatty acyl-CoA biosynthesis (Xenopus tropicalis)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Xenopus tropicalis)
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Xenopus tropicalis)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Xenopus tropicalis)
MECR dimer reduces tdec2-CoA to DEC-CoA (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Metabolism of steroids (Xenopus tropicalis)
Metabolism of steroid hormones (Xenopus tropicalis)
Estrogen biosynthesis (Xenopus tropicalis)
AKR1B15 reduces EST17b to E1 (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Glucocorticoid biosynthesis (Xenopus tropicalis)
CYP11B1 oxidises 11DCORT (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Mineralocorticoid biosynthesis (Xenopus tropicalis)
CYP11B2 18-hydroxylates CORST to 18HCORST (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 11DCORST to CORST (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
CYP11B2 oxidises 18HCORST to ALDO (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Pregnenolone biosynthesis (Xenopus tropicalis)
CYP11A1 cleaves 20a,22b-DHCHOL (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Metabolism of folate and pterines (Xenopus tropicalis)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Nicotinate metabolism (Xenopus tropicalis)
NADK2 dimer phosphorylates NAD+ to NADP+ (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Xenopus tropicalis)
Electron transport from NADPH to Ferredoxin (Xenopus tropicalis)
NADPH transfers electrons to FDXR (Xenopus tropicalis)
NADP+ [mitochondrial matrix]
External Reference Information
External Reference
NADP(3-) [ChEBI:58349]
Participates
as an input of
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Sus scrofa)
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Bos taurus)
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Canis familiaris)
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Rattus norvegicus)
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Mus musculus)
5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Homo sapiens)
5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Sus scrofa)
5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Bos taurus)
5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Canis familiaris)
5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Rattus norvegicus)
5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Mus musculus)
5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Homo sapiens)
AKR1B15 reduces EST17b to E1 (Saccharomyces cerevisiae)
AKR1B15 reduces EST17b to E1 (Schizosaccharomyces pombe)
AKR1B15 reduces EST17b to E1 (Dictyostelium discoideum)
AKR1B15 reduces EST17b to E1 (Caenorhabditis elegans)
AKR1B15 reduces EST17b to E1 (Drosophila melanogaster)
AKR1B15 reduces EST17b to E1 (Gallus gallus)
AKR1B15 reduces EST17b to E1 (Xenopus tropicalis)
AKR1B15 reduces EST17b to E1 (Danio rerio)
AKR1B15 reduces EST17b to E1 (Bos taurus)
AKR1B15 reduces EST17b to E1 (Rattus norvegicus)
AKR1B15 reduces EST17b to E1 (Mus musculus)
AKR1B15 reduces EST17b to E1 (Homo sapiens)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Caenorhabditis elegans)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Drosophila melanogaster)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Gallus gallus)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Xenopus tropicalis)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Sus scrofa)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Bos taurus)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Canis familiaris)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Rattus norvegicus)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Mus musculus)
ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Homo sapiens)
IDH2 dimer decarboxylates isocitrate (Rattus norvegicus)
IDH2 dimer decarboxylates isocitrate (Sus scrofa)
IDH2 dimer decarboxylates isocitrate (Xenopus tropicalis)
ME3 tetramer decarboxylates MAL to PYR (Xenopus tropicalis)
IDH2 dimer decarboxylates isocitrate (Plasmodium falciparum)
ME3 tetramer decarboxylates MAL to PYR (Canis familiaris)
IDH2 dimer decarboxylates isocitrate (Canis familiaris)
ME3 tetramer decarboxylates MAL to PYR (Bos taurus)
IDH2 dimer decarboxylates isocitrate (Bos taurus)
IDH2 dimer decarboxylates isocitrate (Homo sapiens)
IDH2 dimer decarboxylates isocitrate (Mus musculus)
ME3 tetramer decarboxylates MAL to PYR (Mus musculus)
ME3 tetramer decarboxylates MAL to PYR (Homo sapiens)
ME3 tetramer decarboxylates MAL to PYR (Rattus norvegicus)
ME3 tetramer decarboxylates MAL to PYR (Sus scrofa)
IDH2 dimer decarboxylates isocitrate (Danio rerio)
ME3 tetramer decarboxylates MAL to PYR (Danio rerio)
IDH2 dimer decarboxylates isocitrate (Gallus gallus)
ME3 tetramer decarboxylates MAL to PYR (Gallus gallus)
IDH2 dimer decarboxylates isocitrate (Caenorhabditis elegans)
ME3 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)
ME3 tetramer decarboxylates MAL to PYR (Drosophila melanogaster)
as an output of
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Sus scrofa)
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Bos taurus)
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Canis familiaris)
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Rattus norvegicus)
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Mus musculus)
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Homo sapiens)
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Sus scrofa)
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Bos taurus)
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Canis familiaris)
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Rattus norvegicus)
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Mus musculus)
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Sus scrofa)
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Bos taurus)
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Canis familiaris)
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Rattus norvegicus)
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Mus musculus)
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Sus scrofa)
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Bos taurus)
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Canis familiaris)
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Rattus norvegicus)
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Mus musculus)
5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Homo sapiens)
5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Homo sapiens)
3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Homo sapiens)
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Sus scrofa)
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Bos taurus)
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Canis familiaris)
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Rattus norvegicus)
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Mus musculus)
5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Sus scrofa)
5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Bos taurus)
5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Canis familiaris)
5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Rattus norvegicus)
5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Mus musculus)
5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Homo sapiens)
3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Homo sapiens)
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Sus scrofa)
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Bos taurus)
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Canis familiaris)
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Rattus norvegicus)
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Mus musculus)
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Sus scrofa)
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Bos taurus)
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Canis familiaris)
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Rattus norvegicus)
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Mus musculus)
5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Homo sapiens)
3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Homo sapiens)
CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Sus scrofa)
CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Bos taurus)
CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Canis familiaris)
CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Rattus norvegicus)
CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Mus musculus)
CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Homo sapiens)
CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Sus scrofa)
CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Bos taurus)
CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Canis familiaris)
CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Rattus norvegicus)
CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Mus musculus)
CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Homo sapiens)
CYP24A1 24-hydroxylates CTL (Danio rerio)
CYP24A1 24-hydroxylates CTL (Sus scrofa)
CYP24A1 24-hydroxylates CTL (Bos taurus)
CYP24A1 24-hydroxylates CTL (Canis familiaris)
CYP24A1 24-hydroxylates CTL (Rattus norvegicus)
CYP24A1 24-hydroxylates CTL (Mus musculus)
CYP24A1 24-hydroxylates CTL (Homo sapiens)
CYP27A1 27-hydroxylates CHOL (Sus scrofa)
CYP27A1 27-hydroxylates CHOL (Bos taurus)
CYP27A1 27-hydroxylates CHOL (Canis familiaris)
CYP27A1 27-hydroxylates CHOL (Rattus norvegicus)
CYP27A1 27-hydroxylates CHOL (Mus musculus)
CYP27A1 27-hydroxylates CHOL (Homo sapiens)
CYP11B2 oxidises 18HCORST to ALDO (Xenopus tropicalis)
CYP11B2 oxidises 18HCORST to ALDO (Sus scrofa)
CYP11B2 oxidises 18HCORST to ALDO (Bos taurus)
CYP11B2 oxidises 18HCORST to ALDO (Canis familiaris)
CYP11B2 oxidises 18HCORST to ALDO (Rattus norvegicus)
CYP11B2 oxidises 18HCORST to ALDO (Mus musculus)
CYP11B2 oxidises 18HCORST to ALDO (Homo sapiens)
CYP11B2 18-hydroxylates CORST to 18HCORST (Xenopus tropicalis)
CYP11B2 18-hydroxylates CORST to 18HCORST (Sus scrofa)
CYP11B2 18-hydroxylates CORST to 18HCORST (Bos taurus)
CYP11B2 18-hydroxylates CORST to 18HCORST (Canis familiaris)
CYP11B2 18-hydroxylates CORST to 18HCORST (Rattus norvegicus)
CYP11B2 18-hydroxylates CORST to 18HCORST (Mus musculus)
CYP11B2 18-hydroxylates CORST to 18HCORST (Homo sapiens)
CYP11B2 oxidises 11DCORST to CORST (Xenopus tropicalis)
CYP11B2 oxidises 11DCORST to CORST (Sus scrofa)
CYP11B2 oxidises 11DCORST to CORST (Bos taurus)
CYP11B2 oxidises 11DCORST to CORST (Canis familiaris)
CYP11B2 oxidises 11DCORST to CORST (Rattus norvegicus)
CYP11B2 oxidises 11DCORST to CORST (Mus musculus)
CYP11B2 oxidises 11DCORST to CORST (Homo sapiens)
CYP11B1 oxidises 11DCORT (Xenopus tropicalis)
CYP11B1 oxidises 11DCORT (Sus scrofa)
CYP11B1 oxidises 11DCORT (Bos taurus)
CYP11B1 oxidises 11DCORT (Canis familiaris)
CYP11B1 oxidises 11DCORT (Rattus norvegicus)
CYP11B1 oxidises 11DCORT (Mus musculus)
CYP11B1 oxidises 11DCORT (Homo sapiens)
CYP11A1 cleaves 20a,22b-DHCHOL (Gallus gallus)
CYP11A1 cleaves 20a,22b-DHCHOL (Xenopus tropicalis)
CYP11A1 cleaves 20a,22b-DHCHOL (Danio rerio)
CYP11A1 cleaves 20a,22b-DHCHOL (Sus scrofa)
CYP11A1 cleaves 20a,22b-DHCHOL (Bos taurus)
CYP11A1 cleaves 20a,22b-DHCHOL (Canis familiaris)
CYP11A1 cleaves 20a,22b-DHCHOL (Rattus norvegicus)
CYP11A1 cleaves 20a,22b-DHCHOL (Mus musculus)
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Gallus gallus)
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Xenopus tropicalis)
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Danio rerio)
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Sus scrofa)
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Bos taurus)
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Canis familiaris)
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Rattus norvegicus)
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Mus musculus)
Oxidation of cholesterol to 22beta-hydroxycholesterol (Gallus gallus)
Oxidation of cholesterol to 22beta-hydroxycholesterol (Xenopus tropicalis)
Oxidation of cholesterol to 22beta-hydroxycholesterol (Danio rerio)
Oxidation of cholesterol to 22beta-hydroxycholesterol (Sus scrofa)
Oxidation of cholesterol to 22beta-hydroxycholesterol (Bos taurus)
Oxidation of cholesterol to 22beta-hydroxycholesterol (Canis familiaris)
Oxidation of cholesterol to 22beta-hydroxycholesterol (Rattus norvegicus)
Oxidation of cholesterol to 22beta-hydroxycholesterol (Mus musculus)
Oxidation of cholesterol to 22beta-hydroxycholesterol (Homo sapiens)
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Homo sapiens)
CYP11A1 cleaves 20a,22b-DHCHOL (Homo sapiens)
NADK2 dimer phosphorylates NAD+ to NADP+ (Plasmodium falciparum)
NADK2 dimer phosphorylates NAD+ to NADP+ (Caenorhabditis elegans)
NADK2 dimer phosphorylates NAD+ to NADP+ (Drosophila melanogaster)
NADK2 dimer phosphorylates NAD+ to NADP+ (Xenopus tropicalis)
NADK2 dimer phosphorylates NAD+ to NADP+ (Sus scrofa)
NADK2 dimer phosphorylates NAD+ to NADP+ (Bos taurus)
NADK2 dimer phosphorylates NAD+ to NADP+ (Canis familiaris)
NADK2 dimer phosphorylates NAD+ to NADP+ (Rattus norvegicus)
NADK2 dimer phosphorylates NAD+ to NADP+ (Mus musculus)
NADK2 dimer phosphorylates NAD+ to NADP+ (Homo sapiens)
NADK2 dimer phosphorylates NAD+ to NADP+ (Gallus gallus)
HMPhOH is hydroxylated to MDMQ6H2 by HMPhOH monooxygenase (Saccharomyces cerevisiae)
Unknown enzyme hydroxylates DMPhOH (Homo sapiens)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Plasmodium falciparum)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Saccharomyces cerevisiae)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Schizosaccharomyces pombe)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Dictyostelium discoideum)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Caenorhabditis elegans)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Gallus gallus)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Xenopus tropicalis)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Sus scrofa)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Bos taurus)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Canis familiaris)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Rattus norvegicus)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Mus musculus)
GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Homo sapiens)
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Caenorhabditis elegans)
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Drosophila melanogaster)
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Gallus gallus)
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Bos taurus)
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Rattus norvegicus)
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Mus musculus)
TXNRD2 catalyzes the reduction of TXN2 by NADPH (Homo sapiens)
MECR dimer reduces tdec2-CoA to DEC-CoA (Saccharomyces cerevisiae)
MECR dimer reduces tdec2-CoA to DEC-CoA (Schizosaccharomyces pombe)
MECR dimer reduces tdec2-CoA to DEC-CoA (Dictyostelium discoideum)
MECR dimer reduces tdec2-CoA to DEC-CoA (Caenorhabditis elegans)
MECR dimer reduces tdec2-CoA to DEC-CoA (Drosophila melanogaster)
MECR dimer reduces tdec2-CoA to DEC-CoA (Gallus gallus)
MECR dimer reduces tdec2-CoA to DEC-CoA (Xenopus tropicalis)
MECR dimer reduces tdec2-CoA to DEC-CoA (Danio rerio)
MECR dimer reduces tdec2-CoA to DEC-CoA (Sus scrofa)
MECR dimer reduces tdec2-CoA to DEC-CoA (Bos taurus)
MECR dimer reduces tdec2-CoA to DEC-CoA (Canis familiaris)
MECR dimer reduces tdec2-CoA to DEC-CoA (Mus musculus)
MECR dimer reduces tdec2-CoA to DEC-CoA (Homo sapiens)
MECR dimer reduces tdec2-CoA to DEC-CoA (Rattus norvegicus)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Plasmodium falciparum)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Saccharomyces cerevisiae)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Schizosaccharomyces pombe)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Dictyostelium discoideum)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Xenopus tropicalis)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Danio rerio)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Sus scrofa)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Bos taurus)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Canis familiaris)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Rattus norvegicus)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Mus musculus)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Homo sapiens)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Saccharomyces cerevisiae)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Schizosaccharomyces pombe)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Caenorhabditis elegans)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Drosophila melanogaster)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Gallus gallus)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Xenopus tropicalis)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Sus scrofa)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Bos taurus)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Canis familiaris)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Rattus norvegicus)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Mus musculus)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Homo sapiens)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Saccharomyces cerevisiae)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Schizosaccharomyces pombe)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Dictyostelium discoideum)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Caenorhabditis elegans)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Drosophila melanogaster)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Danio rerio)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Canis familiaris)
NNT dimer transfers proton from NADPH to NAD+ (Rattus norvegicus)
NNT dimer transfers proton from NADPH to NAD+ (Xenopus tropicalis)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Xenopus tropicalis)
NNT dimer transfers proton from NADPH to NAD+ (Plasmodium falciparum)
NNT dimer transfers proton from NADPH to NAD+ (Dictyostelium discoideum)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Rattus norvegicus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Homo sapiens)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Mus musculus)
NNT dimer transfers proton from NADPH to NAD+ (Canis familiaris)
NADPH transfers electrons to FDXR (Homo sapiens)
NADPH transfers electrons to FDXR (Mus musculus)
NADPH transfers electrons to FDXR (Rattus norvegicus)
NADPH transfers electrons to FDXR (Canis familiaris)
NADPH transfers electrons to FDXR (Bos taurus)
NADPH transfers electrons to FDXR (Sus scrofa)
NADPH transfers electrons to FDXR (Danio rerio)
NADPH transfers electrons to FDXR (Xenopus tropicalis)
NADPH transfers electrons to FDXR (Gallus gallus)
NADPH transfers electrons to FDXR (Drosophila melanogaster)
NADPH transfers electrons to FDXR (Caenorhabditis elegans)
NADPH transfers electrons to FDXR (Dictyostelium discoideum)
NADPH transfers electrons to FDXR (Schizosaccharomyces pombe)
NADPH transfers electrons to FDXR (Saccharomyces cerevisiae)
NADPH transfers electrons to FDXR (Plasmodium falciparum)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Bos taurus)
NNT dimer transfers proton from NADPH to NAD+ (Bos taurus)
NNT dimer transfers proton from NADPH to NAD+ (Homo sapiens)
NNT dimer transfers proton from NADPH to NAD+ (Mus musculus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Sus scrofa)
NNT dimer transfers proton from NADPH to NAD+ (Danio rerio)
NNT dimer transfers proton from NADPH to NAD+ (Gallus gallus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Gallus gallus)
NNT dimer transfers proton from NADPH to NAD+ (Caenorhabditis elegans)
Other forms of this molecule
NADP+ [mitochondrial matrix]
NADP+ [endosome lumen]
NADP+ [peroxisomal matrix]
NADP+ [cytosol]
Cross References
COMPOUND
C00006
ZINC
000008214733
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