MLH1 SER252TER

Stable Identifier
R-HSA-5444526
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
DNA mismatch repair protein Mlh1, MLH1_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
8128251 Mutation of a mutL homolog in hereditary colon cancer Science 1994
External Reference Information
External Reference
Gene Names
MLH1, COCA2
Chain
initiator methionine:1, chain:2-756
Other Identifiers
0001400064
11717635_a_at
11756036_x_at
13294
16938899
1850_at
202520_s_at
3RBN
4292
4P7A
52707
60714
70868
8078544
A0A024R2S9
A_14_P105437
A_14_P110897
A_23_P69058
A_33_P3419720
AAA17374
AAA82079
AAA85687
AAC50285
AAH06850
AAO22994
AC006583
AC011816
AF001359_f_at
AK295359
AK298324
AK298583
AK316074
AK316264
AY217549
BAG58325
BAG60576
BAG60773
BAH14445
BAH14635
BC006850
CAB013294
CAB070868
CCDS2663
CCDS54562
CCDS54563
CH471055
EAW64483
EAW64484
ENSG00000076242
ENSP00000231790
ENSP00000398272
ENSP00000402564
ENSP00000402667
ENSP00000443665
ENSP00000444286
ENST00000231790
ENST00000435176
ENST00000455445
ENST00000458205
ENST00000536378
ENST00000539477
EntrezGene:4292
g4557756_3p_s_at
GE58891
GO:0000289
GO:0000712
GO:0000793
GO:0000794
GO:0000795
GO:0001673
GO:0002204
GO:0003682
GO:0003697
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0005712
GO:0005715
GO:0006281
GO:0006298
GO:0006303
GO:0006974
GO:0007049
GO:0007060
GO:0007129
GO:0007131
GO:0007140
GO:0007283
GO:0008630
GO:0016020
GO:0016321
GO:0016446
GO:0016447
GO:0016887
GO:0030983
GO:0032137
GO:0032389
GO:0032407
GO:0043060
GO:0045132
GO:0045141
GO:0045143
GO:0045190
GO:0045950
GO:0048298
GO:0048304
GO:0048477
GO:0051257
GO:0051321
HGNC:7127
HPA052707
HPA060714
Hs.195364
ILMN_1788363
IPR002099
IPR003594
IPR013507
IPR014721
IPR014762
IPR020568
IPR032189
LRG_216
LRG_216t1
MIM:120436
MIM:158320
MIM:276300
MIM:609310
MLH1
MLH1-201
MLH1-206
MLH1-212
MLH1-216
MLH1-221
MLH1-222
NM_000249
NM_001167617
NM_001167618
NM_001167619
NM_001258273
NM_001258274
NM_001354620
NP_000240
NP_001161089
NP_001161090
NP_001161091
NP_001245202
NP_001245203
NP_001341544
NP_001341545
NP_001341547
NP_001341548
NP_001341549
PF01119
PF13589
PF16413
PH_hs_0020137
SM01340
TC03000175.hg
U07343
U07418
U07418_at
U17839
U17840
U17841
U17842
U17843
U17844
U17845
U17846
U17847
U17848
U17849
U17851
U17852
U17853
U17854
U17855
U17856
U17857
U40960
U40961
U40962
U40963
U40964
U40965
U40966
U40967
U40968
U40969
U40970
U40971
U40972
U40973
U40974
U40975
U40976
U40977
U40978
uc003cgl.4
uc003cgn.5
uc003cgo.4
uc011ayb.3
uc011ayc.3
uc011ayd.3
UPI0000000C7E
UPI0000EE29B4
UPI000198CA43
XM_005265161
XM_005265163
XM_005265164
XM_005265166
XM_011533727
XM_017006449
XM_017006450
XM_017006451
XP_005265218
XP_005265220
XP_005265221
XP_016861939
Participant Of
Other forms of this molecule
Modified Residues
Name
L-serine removal at 252
Coordinate
252
PsiMod Name
PsiMod Definition
A protein modification that effectively removes or replaces an L-serine.
Disease
Name Identifier Synonyms
colorectal cancer 9256
Interactors (43)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P54278 PMS2  3 0.84 7
 UniProt:P15173 MYOG  1 0.795 8
 UniProt:Q8NA61-2 SPERT      0.781 9
 UniProt:P63010-2 AP2B1      0.781 7
 UniProt:Q6NSI4 RADX      0.764 6
 UniProt:P62328 TMSB4X  2 0.733 16
 IntAct:EBI-11522976 CCDC33      0.696 5
 UniProt:P43361 MAGA8      0.696 5
 UniProt:Q5VWN6 F208B      0.696 5
 UniProt:Q8NA61 SPERT      0.666 4
 UniProt:Q9BX63 BRIP1  2 0.653 11
 UniProt:O94941 UBOX5  1 0.621 3
 UniProt:O75152 ZC3H11A  1 0.621 3
 UniProt:P17661 DES  1 0.602 7
 UniProt:P63261 ACTG1  3 0.602 7
 UniProt:P07858 CTSB  6 0.602 7
 UniProt:P07355 ANXA2  4 0.602 7
 UniProt:Q13813 SPTAN1  6 0.602 7
 UniProt:Q16658 FSCN1  1 0.597 7
 UniProt:P42843 SKP2      0.556 3
 UniProt:P25786 PSMA1  2 0.556 3
 UniProt:P52292 KPNA2  2 0.556 3
 UniProt:P20585 MSH3  2 0.556 3
 UniProt:Q10567-3 AP1B1      0.488 2
 UniProt:Q96PP4 TSG13      0.488 2
 UniProt:Q86UC2 RSPH3      0.488 2
 UniProt:Q5T749 KPRP      0.488 2
 UniProt:Q7Z6R9 TFAP2D  1 0.488 2
 UniProt:Q96GN5 CDA7L      0.488 2
 UniProt:Q96NE9-2 FRMD6      0.488 2
 UniProt:Q14938-5 NFIX      0.488 2
 IntAct:EBI-11985505 KPNA5      0.488 2
 UniProt:Q9UDV6 ZNF212  1 0.488 2
 IntAct:EBI-13352787 FAN1      0.488 2
 UniProt:Q9BX70 BTBD2      0.488 2
 UniProt:Q9H0I2 ENKD1      0.488 2
 UniProt:O76039 CDKL5      0.488 2
 UniProt:Q96KQ4 PPP1R13B  1 0.488 2
 UniProt:P29372-4 MPG      0.488 2
 UniProt:Q8IX06 GOR      0.488 2
 UniProt:O95243-2 MBD4      0.488 6
 UniProt:P26045 PTPN3  1 0.488 4
 UniProt:O15055 PER2  4 0.488 2