Reactome | MSH3 [nucleoplasm]

MSH3 [nucleoplasm]

Stable Identifier

R-HSA-5357519

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DNA mismatch repair protein Msh3, MSH3_HUMAN

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External Reference Information

External Reference

UniProt:P20585 MSH3

Gene Names

MSH3, DUC1, DUG

Chain

chain:1-1137

Reference Genes

BioGPS Gene:4437 MSH3

COSMIC (genes):MSH3 MSH3

CTD Gene:4437 MSH3

dbSNP Gene:4437 MSH3

ENSEMBL:ENSG00000113318 MSH3

HGNC:7326 MSH3

KEGG:hsa:4437 MSH3

Monarch:4437 MSH3

NCBI Gene:4437 MSH3

OMIM:600887 MSH3

UCSC:P20585 MSH3

Reference Transcript

RefSeq:NM_002439.4 MSH3

Other Identifiers

11731032_at

11731033_at

16986748

17126222

1719_at

205887_3p_x_at

205887_PM_x_at

205887_x_at

210947_PM_s_at

210947_s_at

243074_PM_at

243074_at

2817839

2817840

2817841

2817842

2817843

2817844

2817847

2817848

2817849

2817850

2817851

2817856

2817857

2817858

2817865

2817866

2817868

2817870

2817871

2817881

2817882

2817883

2817886

2817887

2817890

2817892

2817895

2817896

2817907

2817908

2817910

2817912

2817913

2817914

2817915

2817916

2817917

4437

8106633

A_14_P116508

A_14_P117964

A_14_P122052

A_14_P123827

A_14_P139372

A_23_P122001

A_24_P203479

GE59286

GE894198

GO:0000166

GO:0002376

GO:0003677

GO:0003690

GO:0003697

GO:0003824

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0006281

GO:0006298

GO:0006310

GO:0006312

GO:0006974

GO:0016020

GO:0016447

GO:0019899

GO:0030983

GO:0032139

GO:0032142

GO:0032181

GO:0032302

GO:0043226

GO:0043570

GO:0045910

GO:0051096

GO:0140097

GO:0140299

GO:0140657

GO:0140664

HMNXSV003035413

Hs.37204.0.A1_3p_at

ILMN_1719471

ILMN_1901532

ILMN_2077130

J04810_s_at

PH_hs_0003124

TC05000400.hg

U61981_at

g181841_3p_a_at

g4505248_3p_at

p33948

Participates

as an input of

as a component of

Other forms of this molecule

MSH3 K383Rfs*32 [nucleoplasm]

Inferred To

MSH3 [nucleoplasm] (Bos taurus)

MSH3 [nucleoplasm] (Canis familiaris)

MSH3 [nucleoplasm] (Gallus gallus)

MSH3 [nucleoplasm] (Mus musculus)

MSH3 [nucleoplasm] (Saccharomyces cerevisiae)

MSH3 [nucleoplasm] (Schizosaccharomyces pombe)

MSH3 [nucleoplasm] (Sus scrofa)

msh3 [nucleoplasm] (Dictyostelium discoideum)

Cross References

RefSeq

NP_002430.3

ENSEMBL

ENST00000265081, ENSP00000265081

OpenTargets

ENSG00000113318

HPA

ENSG00000113318-MSH3

PRO

P20585

Pharos - Targets

P20585

Orphanet

MSH3

PDB

8OM5, 3THW, 3THX, 8OM9, 8OLX, 3THY, 3THZ, 8OMQ, 8OMO, 8OMA

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P43246 MSH2	3	MSH2 [nucleoplasm] (R-HSA-5357525) MSH2 GLN601TER [nucleoplasm] (R-HSA-5577243) MSH2 R406* [nucleoplasm] (R-HSA-5575594)	0.918	14
UniProt:P40692 MLH1	3	MLH1 [nucleoplasm] (R-HSA-912495) MLH1 H329P [nucleoplasm] (R-HSA-5444512) MLH1 S252* [nucleoplasm] (R-HSA-5444526)	0.742	5
UniProt:P12004 PCNA	5	PCNA [nucleoplasm] (R-HSA-68439) MonoUb-K164-PCNA [nucleoplasm] (R-HSA-5651986) ISG-K164,ISG-K168-PCNA [nucleoplasm] (R-HSA-5653768) K63polyUb-K164-PCNA [nucleoplasm] (R-HSA-8943000) monoSUMO1-K164,K254,K-PCNA [nucleoplasm] (R-HSA-4615861)	0.718	6
UniProt:Q9NUM3 S39A9			0.527	2
UniProt:Q8IW19 APLF			0.527	2
UniProt:Q9NXL9 MCM9			0.462	2

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