Reactome | MSH3 [nucleoplasm]

MSH3 [nucleoplasm]

Stable Identifier

R-HSA-5357519

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DNA mismatch repair protein Msh3, MSH3_HUMAN

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External Reference Information

External Reference

UniProt:P20585 MSH3

Gene Names

MSH3, DUC1, DUG

Chain

chain:1-1137

Reference Genes

BioGPS Gene:4437 MSH3

COSMIC (genes):MSH3 MSH3

CTD Gene:4437 MSH3

dbSNP Gene:4437 MSH3

ENSEMBL:ENSG00000113318 MSH3

HGNC:7326 MSH3

KEGG Gene (Homo sapiens):4437 MSH3

Monarch:4437 MSH3

NCBI Gene:4437 MSH3

OMIM:600887 MSH3

UCSC:P20585 MSH3

Reference Transcript

RefSeq:NM_002439.4 MSH3

Other Identifiers

0000840739

11731032_at

11731033_at

16986748

17126222

1719_at

205887_3p_x_at

205887_PM_x_at

205887_x_at

210947_PM_s_at

210947_s_at

2817839

2817840

2817844

2817847

2817848

2817849

2817850

2817851

2817856

2817857

2817858

2817866

2817868

2817870

2817871

2817881

2817882

2817883

2817886

2817887

2817890

2817892

2817895

2817896

2817907

2817908

2817910

2817912

2817913

2817914

2817915

8106633

A_14_P117964

A_14_P122052

A_14_P123827

A_14_P139372

A_23_P122001

A_24_P203479

GE59286

GO:0000166

GO:0002376

GO:0003674

GO:0003677

GO:0003690

GO:0003697

GO:0005515

GO:0005524

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0006259

GO:0006281

GO:0006298

GO:0006312

GO:0006950

GO:0006974

GO:0008150

GO:0016020

GO:0016447

GO:0019899

GO:0030983

GO:0032139

GO:0032142

GO:0032181

GO:0032302

GO:0032991

GO:0034641

GO:0043167

GO:0043226

GO:0043570

GO:0045910

GO:0048856

GO:0051096

GO:0051276

HMNXSV003035413

ILMN_2077130

J04810_s_at

PH_hs_0003124

TC05000400.hg

U61981_at

g181841_3p_a_at

g4505248_3p_at

Participates

as an input of

as a component of

Other forms of this molecule

MSH3 414TER [nucleoplasm]

Inferred To

MSH3 [nucleoplasm] (Bos taurus)

MSH3 [nucleoplasm] (Canis familiaris)

MSH3 [nucleoplasm] (Gallus gallus)

MSH3 [nucleoplasm] (Sus scrofa)

Msh3 [nucleoplasm] (Mus musculus)

Msh3 [nucleoplasm] (Rattus norvegicus)

msh3 [nucleoplasm] (Danio rerio)

msh3 [nucleoplasm] (Dictyostelium discoideum)

msh3 [nucleoplasm] (Schizosaccharomyces pombe)

msh3 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_002430.3

OpenTargets

ENSG00000113318

GeneCards

P20585

HPA

ENSG00000113318-MSH3

Ensembl

ENSG00000113318, ENSP00000265081, ENST00000265081

PRO

P20585

Pharos - Targets

P20585

Orphanet

25490

PDB

3THW, 3THZ, 3THX, 3THY

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P43246 MSH2	3	MSH2 [nucleoplasm] (R-HSA-5357525) MSH2 GLN601TER [nucleoplasm] (R-HSA-5577243) MSH2 R406* [nucleoplasm] (R-HSA-5575594)	0.851	10
UniProt:P40692 MLH1	3	MLH1 S252* [nucleoplasm] (R-HSA-5444526) MLH1 H329P [nucleoplasm] (R-HSA-5444512) MLH1 [nucleoplasm] (R-HSA-912495)	0.742	5
UniProt:P12004 PCNA	5	monoSUMO1-K164,K254,K-PCNA [nucleoplasm] (R-HSA-4615861) K63polyUb-K164-PCNA [nucleoplasm] (R-HSA-8943000) ISG-K164,ISG-K168-PCNA [nucleoplasm] (R-HSA-5653768) MonoUb-K164-PCNA [nucleoplasm] (R-HSA-5651986) PCNA [nucleoplasm] (R-HSA-68439)	0.718	6
UniProt:Q9NXL9 MCM9			0.462	2

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