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MLH1 HIS329PRO

Stable Identifier
R-HSA-5444512
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
DNA mismatch repair protein Mlh1, MLH1_HUMAN
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
MLH1, COCA2
Chain
initiator methionine:1, chain:2-756
Other Identifiers
0001400064
11717635_a_at
11756036_x_at
13294
16938899
1850_at
202520_s_at
2616935
2616936
2616937
2616938
2616941
2616942
2616944
2616946
2616947
2616948
2616949
2616950
2616951
2616958
2616963
2616967
2616968
2616969
2616970
2616971
2616972
2616976
2616977
2616980
2616982
2616985
2616986
3RBN
4292
4P7A
52707
60714
70868
8078544
A0A024R2S9
A_14_P105437
A_14_P110897
A_23_P69058
A_33_P3419720
AAA17374
AAA82079
AAA85687
AAC50285
AAH06850
AAO22994
AC006583
AC011816
AF001359_f_at
AK295359
AK298324
AK298583
AK316074
AK316264
AY217549
BAG58325
BAG60576
BAG60773
BAH14445
BAH14635
BC006850
CAB013294
CAB070868
CCDS2663
CCDS54562
CCDS54563
CH471055
EAW64483
EAW64484
ENSG00000076242
ENSP00000231790
ENSP00000398272
ENSP00000402564
ENSP00000402667
ENSP00000416687
ENSP00000443665
ENSP00000444286
ENST00000231790
ENST00000435176
ENST00000455445
ENST00000456676
ENST00000458205
ENST00000536378
ENST00000539477
EntrezGene:4292
g4557756_3p_s_at
GE58891
GO:0000003
GO:0000166
GO:0000228
GO:0000289
GO:0000712
GO:0000793
GO:0000794
GO:0000795
GO:0001673
GO:0002204
GO:0002376
GO:0003674
GO:0003677
GO:0003682
GO:0003697
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0005712
GO:0005715
GO:0006259
GO:0006281
GO:0006298
GO:0006303
GO:0006950
GO:0006974
GO:0007010
GO:0007049
GO:0007059
GO:0007060
GO:0007129
GO:0007131
GO:0007140
GO:0007165
GO:0007283
GO:0008150
GO:0008219
GO:0008630
GO:0009056
GO:0016020
GO:0016321
GO:0016446
GO:0016447
GO:0016887
GO:0022607
GO:0030154
GO:0030983
GO:0032137
GO:0032300
GO:0032389
GO:0032407
GO:0034641
GO:0034655
GO:0043060
GO:0043167
GO:0043226
GO:0043234
GO:0045132
GO:0045141
GO:0045143
GO:0045190
GO:0045950
GO:0048298
GO:0048304
GO:0048477
GO:0048856
GO:0051257
GO:0051276
GO:0051321
HGNC:7127
HPA052707
HPA060714
ILMN_1788363
IPR002099
IPR003594
IPR011186
IPR013507
IPR014721
IPR014762
IPR020568
IPR032189
IPR036890
LRG_216
LRG_216t1
MIM:120436
MIM:158320
MIM:276300
MIM:609310
MLH1
MLH1-201
MLH1-206
MLH1-212
MLH1-216
MLH1-221
MLH1-222
NM_000249
NM_001167617
NM_001167618
NM_001167619
NM_001258273
NM_001258274
NM_001354617
NM_001354620
NP_000240
NP_001161089
NP_001161090
NP_001161091
NP_001245202
NP_001245203
NP_001341544
NP_001341545
NP_001341546
NP_001341547
NP_001341548
NP_001341549
PF01119
PF13589
PF16413
PH_hs_0020137
SM01340
TC03000175.hg
U07343
U07418
U07418_at
U17839
U17840
U17841
U17842
U17843
U17844
U17845
U17846
U17847
U17848
U17849
U17851
U17852
U17853
U17854
U17855
U17856
U17857
U40960
U40961
U40962
U40963
U40964
U40965
U40966
U40967
U40968
U40969
U40970
U40971
U40972
U40973
U40974
U40975
U40976
U40977
U40978
uc003cgl.4
uc003cgn.5
uc003cgo.4
uc011ayb.3
uc011ayc.3
uc011ayd.3
UPI0000000C7E
UPI0000EE29B4
UPI000198CA43
XM_005265161
XM_005265163
XM_005265164
XM_005265166
XM_011533727
XM_017006449
XM_017006450
XM_017006451
XP_005265218
XP_005265220
XP_005265221
XP_016861939
Participant Of
Other forms of this molecule
Modified Residues
Name
L-histidine 329 replaced with L-proline
Coordinate
329
PsiMod HEY
A protein modification that effectively removes or replaces an L-histidine.
A protein modification that effectively converts a source amino acid residue to L-proline.
Disease
Name Identifier Synonyms
colorectal cancer 9256
Interactors (68)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P15173 MYOG  1 0.795 8
 UniProt:Q8NA61-2 SPERT      0.781 9
 UniProt:P63010-2 AP2B1      0.781 7
 UniProt:P54278 PMS2  3 0.764 5
 UniProt:Q6NSI4 RADX      0.764 6
 UniProt:P62328 TMSB4X  2 0.733 16
 UniProt:Q5VWN6 F208B      0.696 5
 UniProt:P52292 KPNA2  2 0.696 5
 IntAct:EBI-11522976 CCDC33      0.696 5
 UniProt:P43361 MAGA8      0.696 5
 UniProt:Q8NA61 SPERT      0.666 4
 UniProt:Q9BX63 BRIP1  2 0.653 11
 UniProt:O94941 UBOX5  1 0.621 3
 UniProt:O75152 ZC3H11A  1 0.621 3
 UniProt:Q13813 SPTAN1  6 0.602 7
 UniProt:P17661 DES  1 0.602 7
 UniProt:P63261 ACTG1  3 0.602 7
 UniProt:P07858 CTSB  6 0.602 7
 UniProt:P07355 ANXA2  4 0.602 7
 UniProt:Q16658 FSCN1  1 0.597 7
 UniProt:P25786 PSMA1  2 0.556 3
 UniProt:P42843 SKP2      0.556 3
 UniProt:P20585 MSH3  2 0.556 3
 UniProt:Q10567-3 AP1B1      0.488 2
 UniProt:Q96PP4 TSG13      0.488 2
 IntAct:EBI-17189293 AL513477.1      0.488 2
 UniProt:Q6PF18 MORN3      0.488 2
 UniProt:Q5T749 KPRP      0.488 2
 UniProt:Q7Z6R9 TFAP2D  1 0.488 2
 UniProt:Q96GN5 CDA7L      0.488 2
 UniProt:P78356-2 PIP4K2B      0.488 2
 UniProt:Q9Y247 FA50B      0.488 2
 UniProt:Q96NE9-2 FRMD6      0.488 2
 UniProt:Q86YD7 F90A1      0.488 2
 IntAct:EBI-11985505 KPNA5      0.488 2
 UniProt:Q9UDV6 ZNF212  1 0.488 2
 UniProt:Q9NU63-3 ZFP57      0.488 2
 UniProt:Q9H0I2 ENKD1      0.488 2
 UniProt:Q8WWY6 MB3L1      0.488 2
 UniProt:O76039 CDKL5      0.488 2
 UniProt:P29372-4 MPG      0.488 2
 UniProt:H7C1N6 H7C1N6      0.488 2
 UniProt:Q8TF47 ZFP90  1 0.488 2
 UniProt:Q08117-2 AES      0.488 2
 UniProt:Q8IX06 GOR      0.488 2
 UniProt:P60323-2 P603232      0.488 2
 UniProt:O95243-2 MBD4      0.488 4
 UniProt:Q5RL73 RBM48      0.488 2
 UniProt:Q6S9Z5 ZN474      0.488 2
 UniProt:Q86UC2 RSPH3      0.488 2
 UniProt:Q9UDW3 ZMAT5  1 0.488 2
 UniProt:Q86W67 F228A      0.488 2
 UniProt:P0DN76 U2AF5      0.488 2
 UniProt:O95232-2 O952322      0.488 2
 UniProt:Q6MZQ0 PRR5L      0.488 2
 UniProt:Q14938-5 NFIX      0.488 2
 IntAct:EBI-13352787 FAN1      0.488 2
 UniProt:Q9BX70 BTBD2      0.488 2
 UniProt:O00746 NME4  1 0.488 2
 UniProt:Q96KQ4 PPP1R13B  1 0.488 2
 UniProt:Q5JTZ5 CI152      0.488 2
 UniProt:Q9NQV7 PRDM9  1 0.488 2
 IntAct:EBI-11957111 SP3P      0.488 2
 UniProt:Q6NX45 ZNF774  1 0.488 2
 UniProt:O15055 PER2  4 0.488 2
 UniProt:Q9ULR0 ISY1  1 0.488 2
 UniProt:P26045 PTPN3  1 0.488 2
 UniProt:Q9H3P2 NELFA  1 0.488 2