Reactome | ATF3 [nucleoplasm]

ATF3 [nucleoplasm]

Stable Identifier

R-HSA-535543

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Cyclic AMP-dependent transcription factor ATF-3, ATF3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P18847 ATF3

Gene Names

ATF3

Chain

chain:1-181

Reference Genes

COSMIC (genes):ATF3 ATF3

dbSNP Gene:467 ATF3

ENSEMBL:ENSG00000162772 ATF3

Participates

as an input of

ATF4, CEBPB, and ATF3 bind the CHAC1 promoter (Homo sapiens)

as a component of

ATF3:ATF4:CEBPB:CHAC1 gene [nucleoplasm] (Homo sapiens)

as an output of

Expression of ATF3 (Homo sapiens)

Interactors (22)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35638 DDIT3	1	DDIT3 [nucleoplasm] (R-HSA-381110)	0.958	38
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.85	10
UniProt:P17275 JUNB	1	JUNB [nucleoplasm] (R-HSA-2186795)	0.829	7
UniProt:P18848 ATF4	2	ATF4 [cytosol] (R-HSA-381084) ATF4 [nucleoplasm] (R-HSA-381016)	0.799	9
UniProt:P53567 CEBPG	1	CEBPG [nucleoplasm] (R-HSA-9644320)	0.713	5
UniProt:Q9NR55 BATF3			0.713	5
UniProt:P15336 ATF2	2	p-T69,T71-ATF2 [nucleoplasm] (R-HSA-450243) ATF2 [nucleoplasm] (R-HSA-450336)	0.713	5
UniProt:P18847 ATF3	1	ATF3 [nucleoplasm] (R-HSA-535543)	0.667	3
UniProt:Q16236 NFE2L2	13	p-S40-NFE2L2 [nucleoplasm] (R-HSA-9715109) p-S,T-NFE2L2 [nucleoplasm] (R-HSA-9715110) p-S40-NFE2L2 [cytosol] (R-HSA-8932290) p-S,T-NFE2L2 [cytosol] (R-HSA-8932311) NFE2L2 [cytosol] (R-HSA-201566) p-S,T-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760033) p-S40-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760018) ub-NFE2L2 [cytosol] (R-HSA-9758077) ub-p-S335, S338,T-NFE2L2 [nucleoplasm] (R-HSA-9762055) ub-p-S40, S335, S338- NFE2L2 [nucleoplasm] (R-HSA-9762058) p-S344, S347,T-NFE2L2 [nucleoplasm] (R-HSA-9762048) p-S40, S344, S347- NFE2L2 [nucleoplasm] (R-HSA-9762050) p-S,T,S558-NFE2L2 [nucleoplasm] (R-HSA-9795736)	0.625	5
UniProt:P17535 JUND	1	JUND [nucleoplasm] (R-HSA-9009924)	0.59	3
UniProt:P17544 ATF7			0.59	3
UniProt:A0A6Q8PF08 A0A6Q8PF08			0.556	3
UniProt:P54253 ATX1			0.556	6
UniProt:P09936 UCHL1	1	UCHL1 [cytosol] (R-HSA-5660679)	0.556	3
UniProt:Q14203-5 DCTN1			0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:Q92870-2 Q928702			0.556	3
UniProt:Q13148 TADBP			0.556	6
UniProt:P37840 SNCA	5	SNCA [cytosol] (R-HSA-5658500) p-S129-SNCA [cytosol] (R-HSA-9836432) Ub-SNCA [cytosol] (R-HSA-5660754) SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569)	0.556	3
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.508	3
UniProt:O95644 NFATC1	3	p-12S-NFATC1 [cytosol] (R-HSA-2025953) p-S257-NFATC1 [cytosol] (R-HSA-2685618) p-S257-NFATC1 [nucleoplasm] (R-HSA-2025935)	0.499	2
UniProt:O60880 SH2D1A	1	SH2D1A [cytosol] (R-HSA-5685108)	0.488	2

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