Reactome | UniProt:P37840 SNCA

UniProt:P37840 SNCA

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

SYUA_HUMAN, A8K2A4, Q13701, Q4JHI3, Q6IAU6

List of interactors in Reactome

Interactors (57)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P37840	3	p-S129-SNCA [cytosol] (R-HSA-9836432) SNCA [cytosol] (R-HSA-5658500) Ub-SNCA [cytosol] (R-HSA-5660754)	0.99	51
Q9Y6H5	3	K63Ub-SNCAIP [cytosol] (R-HSA-5667114) PolyUb-SNCAIP [cytosol] (R-HSA-5667104) SNCAIP [cytosol] (R-HSA-5333629)	0.825	22
P02649	3	APOE [early endosome] (R-HSA-2429687) APOE [extracellular region] (R-HSA-174646) APOE-4 [extracellular region] (R-HSA-9711070)	0.809	11
P10636	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521)	0.681	12
P05067	12	APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-713) [extracellular region] (R-HSA-879340) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325)	0.659	6
Q07812	3	BAX [cytosol] (R-HSA-139916) BAX [mitochondrial outer membrane] (R-HSA-139949) BAX activated [cytosol] (R-HSA-139907)	0.659	4
Q9UNE7	1	STUB1 [cytosol] (R-HSA-975970)	0.633	4
P63027	12	VAMP2 [cytoplasmic vesicle membrane] (R-HSA-1449630) VAMP2 [plasma membrane] (R-HSA-210516) VAMP2 [secretory granule membrane] (R-HSA-376363) VAMP2 [synaptic vesicle membrane] (R-HSA-181517) VAMP2(2-58) [cytosol] (R-HSA-194815) VAMP2(2-59) [cytosol] (R-HSA-194797) VAMP2(2-76) [cytosol] (R-HSA-194802) VAMP2(2-81) [cytosol] (R-HSA-5250970) VAMP2(59-116) [synaptic vesicle membrane] (R-HSA-5250891) VAMP2(60-116) [synaptic vesicle membrane] (R-HSA-5250615) VAMP2(77-116) [synaptic vesicle membrane] (R-HSA-5228355) VAMP2(82-116) [synaptic vesicle membrane] (R-HSA-5250961)	0.632	5
P02647	3	APOA1(19-266) [extracellular region] (R-HSA-264771) APOA1(25-266) [extracellular region] (R-HSA-174720) APOA1(25-267) [endoplasmic reticulum lumen] (R-HSA-174640)	0.623	3
P00519	5	ABL1 [cytosol] (R-HSA-375987) ABL1 [nucleoplasm] (R-HSA-5686579) p-S456-ABL1 [nucleoplasm] (R-HSA-5686576) p-Y226,Y393-ABL1 [nucleoplasm] (R-HSA-8985251) p-Y393-ABL1 [cytosol] (R-HSA-9865161)	0.602	3
17552	4	GDP [cytoplasmic vesicle membrane] (R-ALL-1996292) GDP [endoplasmic reticulum lumen] (R-ALL-1467290) GDP [nucleoplasm] (R-ALL-111349) GDP [plasma membrane] (R-ALL-114549)	0.582	5
P00441	1	SOD1 [mitochondrial intermembrane space] (R-HSA-3777082)	0.567	9
P0DTC9	9	ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) N [cytosol] (R-COV-9694300) N [plasma membrane] (R-COV-9694356) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) p-11S,2T-N [cytosol] (R-COV-9729264) p-8S,2T-N [cytosol] (R-COV-9729277) p-8S-N [cytosol] (R-COV-9729335) p-S188,206-N [cytosol] (R-COV-9729324) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340)	0.558	2
A0AVK6	1	E2F8 [nucleoplasm] (R-HSA-8952990)	0.556	3
O00308	1	WWP2 [cytosol] (R-HSA-6807279)	0.556	3
O00471	1	EXOC5 [cytosol] (R-HSA-265045)	0.556	3
O00560	1	SDCBP [cytosol] (R-HSA-373639)	0.556	3
O15392	3	BIRC5 [cytosol] (R-HSA-50851) BIRC5 [nucleoplasm] (R-HSA-4655344) ub-BIRC5 [cytosol] (R-HSA-8955933)	0.556	3
O75925	1	PIAS1 [nucleoplasm] (R-HSA-877307)	0.556	3
P02795	1	MT2A [cytosol] (R-HSA-1031707)	0.556	3
P06241	3	FYN [cytosol] (R-HSA-200917) p-Y420-FYN [cytosol] (R-HSA-391821) p-Y531-FYN [cytosol] (R-HSA-391819)	0.556	3
P07437	1	TUBB [cytosol] (R-HSA-9020816)	0.556	3
P07948	4	LYN [cytosol] (R-HSA-354251) LYN [plasma membrane] (R-HSA-197943) MyrG2-PalmC3-LYN [plasma membrane] (R-HSA-9606875) p-Y397-LYN [plasma membrane] (R-HSA-2454229)	0.556	3
P09017	1	HOXC4 [nucleoplasm] (R-HSA-5617871)	0.556	3
P17252	3	p-T497,T638,S657-PRKCA [cytosol] (R-HSA-4332337) PRKCA [cytosol] (R-HSA-58196) PRKCA [nucleoplasm] (R-HSA-450530)	0.556	3
P17980	1	PSMC3 [cytosol] (R-HSA-68774)	0.556	6
P18847	1	ATF3 [nucleoplasm] (R-HSA-535543)	0.556	3
P19474	1	TRIM21 [cytosol] (R-HSA-976051)	0.556	3
P55212	1	CASP6 (1-293) [cytosol] (R-HSA-6798132)	0.556	3
P62191	1	PSMC1 [cytosol] (R-HSA-68768)	0.556	3
P62987	3	RPL40 [cytosol] (R-HSA-72476) UBA52(1-128) [cytosol] (R-HSA-8853517) UBA52(1-76) [cytosol] (R-HSA-939203)	0.556	3
P99999	6	AcK-CYCS [mitochondrial intermembrane space] (R-HSA-5688308) apo-CYCS [mitochondrial inner membrane] (R-HSA-352608) CYCS [cytosol] (R-HSA-53259) CYCS [mitochondrial intermembrane space] (R-HSA-114244) Cytochrome c (oxidised) [mitochondrial inner membrane] (R-HSA-352607) Cytochrome c (reduced) [mitochondrial inner membrane] (R-HSA-352609)	0.556	3
Q07817	2	BCL2L1 [cytosol] (R-HSA-50771) BCL2L1 [mitochondrial outer membrane] (R-HSA-114236)	0.556	3
Q13501	2	K7 ub-SQSTM1 [cytosol] (R-HSA-9759088) SQSTM1 [cytosol] (R-HSA-193937)	0.556	3
Q13569	3	monoSUMO1-K330-TDG [nucleoplasm] (R-HSA-4551718) polySUMO2,3-K330-TDG [nucleoplasm] (R-HSA-4551628) TDG [nucleoplasm] (R-HSA-65812)	0.556	3
Q16143	1	SNCB [cytosol] (R-HSA-5660390)	0.556	3
Q5S007	1	LRRK2 [cytosol] (R-HSA-5661173)	0.556	6
Q6VY07	1	PACS1 [cytosol] (R-HSA-167634)	0.556	3
Q8IYW5	2	monoSUMO1-RNF168 [nucleoplasm] (R-HSA-4551750) RNF168 [nucleoplasm] (R-HSA-4551605)	0.556	3
Q969S8	1	HDAC10 [nucleoplasm] (R-HSA-351579)	0.556	3
Q96NC0	1	ZMAT2 [nucleoplasm] (R-HSA-9770248)	0.556	3
Q9BYZ2	1	LDHAL6B [mitochondrial matrix] (R-HSA-6807613)	0.556	3
Q9H0E2	1	TOLLIP [cytosol] (R-HSA-446885)	0.556	3
Q9H0Y0	1	ATG10 [cytosol] (R-HSA-5671733)	0.556	3
Q9HD42	1	CHMP1A [cytosol] (R-HSA-917721)	0.556	3
Q9UIH9	1	KLF15 [nucleoplasm] (R-HSA-8878735)	0.556	3
P00533	2	EGFR [plasma membrane] (R-HSA-179837) EGFRvIII [plasma membrane] (R-HSA-1214162)	0.553	2
P49841	2	GSK3B [cytosol] (R-HSA-2997551) GSK3B [nucleoplasm] (R-HSA-2022823)	0.544	2
P42858	1	HTT [nucleoplasm] (R-HSA-9023590)	0.543	4
Q01959	1	SLC6A3 [plasma membrane] (R-HSA-379482)	0.539	3
P0CG48	10	UBC [cytosol] (R-HSA-8853531) UBC(1-76) [cytosol] (R-HSA-939188) UBC(153-228) [cytosol] (R-HSA-939258) UBC(229-304) [cytosol] (R-HSA-939192) UBC(305-380) [cytosol] (R-HSA-939232) UBC(381-456) [cytosol] (R-HSA-939191) UBC(457-532) [cytosol] (R-HSA-939184) UBC(533-608) [cytosol] (R-HSA-939239) UBC(609-684) [cytosol] (R-HSA-939165) UBC(77-152) [cytosol] (R-HSA-939164)	0.524	2
Q9Y6H5	1	SNCAIP-1A [cytosol] (R-HSA-5667110)	0.524	2
Q61327	1	SLC6A3 [plasma membrane] (R-MMU-379482)	0.518	5
O88507	1	Cntfr [plasma membrane] (R-MMU-5696438)	0.512	4
Q16623	1	STX1A [plasma membrane] (R-HSA-449128)	0.499	2
P00520	6	Abl1 [cytosol] (R-MMU-449189) ABL1 [cytosol] (R-MMU-375987) ABL1 [nucleoplasm] (R-MMU-5686579) p-Y226,Y393-ABL1 [nucleoplasm] (R-MMU-8985251) phospho-p-S456-ABL1 [nucleoplasm] (R-MMU-5686576) phospho-p-Y393-ABL1 [cytosol] (R-MMU-9865161)	0.463	2
Q08406	1	Cntfr [plasma membrane] (R-RNO-5696438)	0.462	2

Cite Us!