TPM4(2-222)insV-p-7Y-ALK(1059-1620) fusion [cytosol]

Stable Identifier
R-HSA-9710841
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Tropomyosin alpha-4 chain, TPM4_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
10934142 TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors

Pinkus, GS, Pinkus, JL, Rubin, BP, Perez-Atayde, A, Hibbard, MK, Fletcher, JA, Xiao, S, Yi, ES, Fletcher, CD, Lawrence, B, Dal Cin, P

Am J Pathol 2000
External Reference Information
External Reference
UniProt:P67936 TPM4
Gene Names
TPM4
Chain
initiator methionine:, chain:2-248
Reference Genes
BioGPS Gene:7171 TPM4
COSMIC (genes):TPM4 TPM4
CTD Gene:7171 TPM4
dbSNP Gene:7171 TPM4
ENSEMBL:ENSG00000167460 TPM4
HGNC:12013 TPM4
Monarch:7171 TPM4
NCBI Gene:7171 TPM4
OMIM:600317 TPM4
UCSC:P67936 TPM4
Reference Transcript
Other Identifiers
11727782_a_at
11727783_s_at
11727784_x_at
11748400_s_at
11748401_x_at
1567107_PM_s_at
1567107_s_at
16859253
16859268
17123152
17123154
17124988
209344_PM_at
209344_at
212481_PM_s_at
212481_s_at
235094_PM_at
235094_at
235922_PM_at
235922_at
2614801
2614803
2614804
3102324
3102327
3102328
33866_at
3823515
3823516
3823517
3823519
3823520
3823521
3823522
3823523
3823524
3823525
3823526
3823527
3823528
3823532
3823534
3823535
3823536
3823537
3823538
3823539
3823540
3823541
3823542
3823543
3823544
3823545
3823546
3823547
3823548
3823549
3823550
7171
8026513
8180349
82467_at
86198_at
A_14_P107669
A_14_P108658
A_23_P141974
A_24_P82880
A_32_P28284
GE61356
GE88029
GO:0001649
GO:0001725
GO:0002102
GO:0003012
GO:0003779
GO:0005198
GO:0005509
GO:0005515
GO:0005737
GO:0005829
GO:0005856
GO:0005862
GO:0005884
GO:0005925
GO:0006936
GO:0007015
GO:0008092
GO:0008307
GO:0016020
GO:0030154
GO:0030220
GO:0030863
GO:0042802
GO:0042803
GO:0043226
GO:0046872
GO:0046982
GO:0051015
GO:0070062
HMNXSV003043181
HMNXSV003052535
Hs.137526.0.A1_3p_at
Hs.194339.0.A1_3p_at
Hs.250641.1.S1_3p_a_at
Hs2.438676.1.S1_3p_s_at
PH_hs_0027325
TC19000316.hg
X05276_at
g12803958_3p_x_at
Participates
as a component of
Other forms of this molecule
TPM4 [cytosol]
TPM4(2-222)insV-ALK(1059-1620) fusion [cytosol]
Modified Residues
Name
Insertion of residues 1059 to 1620 at 223 from UniProt:Q9UM73 ALK
Coordinate
223
Name
Replacement of residues 222 to 222 by EV
Name
O4'-phospho-L-tyrosine at 1278
Coordinate
1278
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1282
Coordinate
1282
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1283
Coordinate
1283
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1358
Coordinate
1358
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1507
Coordinate
1507
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1604
Coordinate
1604
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Cross References
COSMIC
ENSEMBL
OpenTargets
HPA
PRO
Pharos - Targets
GlyGen
Orphanet
HMDB Protein
Interactors (2)
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