O-glycosyl 3a [endolysosome membrane]

Stable Identifier
R-COV-9754541
Type
Protein [EntityWithAccessionedSequence]
Species
Severe acute respiratory syndrome coronavirus 2
Compartment
Synonyms
P0DTC3
Locations in the PathwayBrowser
General
SARS-CoV-2 mRNA2 open reading frame has a length of 3,822 nt and encodes the 1,273 aa spike preprotein (Wu et al, 2020).
Literature References
PubMed ID Title Journal Year
16474139 Glycosylation of the severe acute respiratory syndrome coronavirus triple-spanning membrane proteins 3a and M

de Haan, CA, de Groot, RJ, Oostra, M, Rottier, PJ

J. Virol. 2006
External Reference Information
External Reference
Gene Names
3a
Chain
chain:1-275
Reference Transcript
Participates
Other forms of this molecule
Inferred From
Modified Residues
Name
O-glycosyl-L-threonine at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O3-glycosylthreonine.
Disease
Name Identifier Synonyms
COVID-19 DOID:0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Cross References
GlyGen
Interactors (44)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96JC1 VPS39  1 0.956 19
 UniProt:Q96S66 CLCC1      0.875 9
 UniProt:Q9H270 VPS11  1 0.823 7
 UniProt:Q9Y673 ALG5  1 0.738 4
 UniProt:P09601 HMOX1  4 0.738 4
 UniProt:P0DTC3 3a  9 0.716 4
 UniProt:P49754 VPS41  1 0.695 4
 UniProt:Q9UH99 SUN2  1 0.659 3
 UniProt:Q8NBJ7 SUMF2  1 0.659 3
 UniProt:Q8N6S5 AR6P6      0.643 3
 UniProt:Q8IWR1 TRI59      0.643 3
 UniProt:Q01518 CAP1  3 0.613 3
 UniProt:Q9P2Y5 UVRAG  2 0.602 6
 UniProt:Q12846 STX4  4 0.602 4
 UniProt:P51809 VAMP7  6 0.602 4
 UniProt:Q96HE7 ERO1A  1 0.547 2
 UniProt:P07205 PGK2  1 0.547 2
 UniProt:P50454 SERPINH1  1 0.547 2
 UniProt:P35609 ACTN2  3 0.547 2
 UniProt:Q8NBS9 TXNDC5  4 0.547 2
 UniProt:Q92545 TM131      0.547 2
 UniProt:Q9H0V9 LMAN2L  3 0.547 2
 UniProt:P16422 EPCAM  1 0.527 2
 UniProt:P51153 RAB13  4 0.527 2
 UniProt:Q15005 SPCS2  1 0.527 2
 UniProt:Q9Y4P3 TBL2      0.527 2
 UniProt:Q9NRX4 PHP14      0.527 2
 UniProt:Q9Y617 PSAT1  1 0.527 2
 UniProt:P61106 RAB14  7 0.527 2
 UniProt:Q9UNN8 PROCR  2 0.527 2
 UniProt:P30519 HMOX2  3 0.527 2
 UniProt:P04439 HLA-A  9 0.527 2
 UniProt:O75976 CPD  3 0.527 2
 UniProt:P0DTD8 NS7B      0.519 3
 UniProt:Q8NAF0 ZN579      0.499 2
 UniProt:P0DTD1-PRO_0000449632 REP      0.488 2
 UniProt:Q9P253 VPS18  1 0.483 2
 UniProt:Q8NHV4 NEDD1  1 0.483 2
 UniProt:Q9H269 VPS16  1 0.483 2
 UniProt:Q12913 PTPRJ  2 0.483 2
 UniProt:P42765 ACAA2  1 0.482 2
 UniProt:Q9H3K2 GHITM      0.482 2
 UniProt:Q96GS4 BORC6      0.463 2
 UniProt:Q9GZU1 MCOLN1  2 0.463 2
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