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HMOX2 [specific granule membrane]
Stable Identifier
R-HSA-6799628
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
specific granule membrane
Synonyms
Heme oxygenase 2, HO2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [specific granule membrane] (Homo sapiens)
HMOX2 [specific granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P30519 HMOX2
Gene Names
HMOX2, HO2
Chain
initiator methionine:, chain:2-316, chain:2-295
Reference Genes
BioGPS Gene:3163 HMOX2
COSMIC (genes):HMOX2 HMOX2
CTD Gene:3163 HMOX2
dbSNP Gene:3163 HMOX2
ENSEMBL:ENSG00000103415 HMOX2
ENSEMBL_homo_sapiens_GENE:ENSG00000103415.12 HMOX2
ENSEMBL_homo_sapiens_GENE:ENSG00000277424.4 HMOX2
HGNC:5014 HMOX2
KEGG Gene (Homo sapiens):3163 HMOX2
Monarch:3163 HMOX2
NCBI Gene:3163 HMOX2
OMIM:141251 HMOX2
UCSC:P30519 HMOX2
Reference Transcript
RefSeq:NM_001286268.1 HMOX2
RefSeq:NM_001286270.1 HMOX2
RefSeq:NM_001127205.1 HMOX2
RefSeq:NM_002134.3 HMOX2
RefSeq:NM_001286267.1 HMOX2
RefSeq:XM_017023197.1 HMOX2
RefSeq:NM_001286269.1 HMOX2
RefSeq:NM_001286271.1 HMOX2
RefSeq:NM_001127204.1 HMOX2
RefSeq:XM_017023196.1 HMOX2
RefSeq:NM_001127206.2 HMOX2
Other Identifiers
11729615_a_at
11755424_a_at
16815528
218120_PM_s_at
218120_s_at
218121_PM_at
218121_at
3163
3646200
3646202
3646204
3646205
3646206
3646207
3646211
3646212
3646213
3646214
3646216
3646217
3646219
3646220
3646221
3646222
3646223
37916_at
64632_at
7992987
A_14_P200412
A_23_P100501
A_24_P381945
GE80151
GO:0001666
GO:0003824
GO:0004392
GO:0005515
GO:0005783
GO:0005789
GO:0005886
GO:0006788
GO:0006979
GO:0016020
GO:0016491
GO:0020037
GO:0031410
GO:0035579
GO:0042167
GO:0043226
GO:0043231
GO:0046872
HMNXSV003058246
ILMN_1658807
PH_hs_0014732
PH_hs_0035751
S34389_at
TC16000131.hg
g416226_3p_a_at
g8051607_3p_at
Participates
as a member of
Specific granule membrane proteins [specific granule membrane] (Homo sapiens)
Other forms of this molecule
HMOX2 [plasma membrane]
HMOX2 [endoplasmic reticulum membrane]
Inferred To
HMOX2 [specific granule membrane]
(Bos taurus)
HMOX2 [specific granule membrane]
(Canis familiaris)
HMOX2 [specific granule membrane]
(Drosophila melanogaster)
HMOX2 [specific granule membrane]
(Gallus gallus)
HMOX2 [specific granule membrane]
(Mus musculus)
HMOX2 [specific granule membrane]
(Rattus norvegicus)
HMOX2 [specific granule membrane]
(Sus scrofa)
hmox2b [specific granule membrane]
(Danio rerio)
hmox2 [specific granule membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001273197.1
,
XP_016878685.1
,
NP_002125.3
,
NP_001273199.1
,
NP_001273196.1
,
NP_001120678.1
,
NP_001120676.1
,
NP_001273198.1
,
NP_001273200.1
,
XP_016878686.1
,
NP_001120677.1
Guide to Pharmacology - Targets
1442
OpenTargets
ENSG00000103415
GeneCards
P30519
HPA
ENSG00000103415-HMOX2
Ensembl
ENST00000575120
,
ENST00000398595
,
ENSP00000481295
,
ENSP00000481811
,
ENSP00000394103
,
ENST00000621065
,
ENST00000458134
,
ENSP00000478785
,
ENSP00000488769
,
ENST00000632458
,
ENST00000406590
,
ENSP00000385100
,
ENST00000612525
,
ENST00000615778
,
ENST00000631540
,
ENST00000414777
,
ENSP00000483319
,
ENSG00000103415
,
ENSP00000487673
,
ENSP00000484422
,
ENSP00000484423
,
ENSP00000391637
,
ENSP00000488880
,
ENSP00000484467
,
ENST00000619913
,
ENSP00000460926
,
ENSG00000277424
,
ENSP00000488579
,
ENST00000620445
,
ENST00000631677
,
ENSP00000381595
,
ENST00000219700
,
ENST00000570646
,
ENST00000622146
,
ENST00000619528
,
ENST00000633319
,
ENSP00000459214
,
ENSP00000219700
PRO
P30519
Pharos - Targets
P30519
HMDB Protein
HMDBP00151
PDB
5UC8
,
2Q32
,
5UC9
,
2RGZ
,
4WMH
,
5UCA
,
2QPP
Interactors (14)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.556
3
UniProt:P06241 FYN
6
p-S21,Y420-FYN [cytosol]
(R-HSA-5218745)
p-Y531-FYN [cytosol]
(R-HSA-391819)
MyrG2-PalmC3,6-FYN [plasma membrane]
(R-HSA-9606873)
p-Y420-FYN [cytosol]
(R-HSA-391821)
MyrG-p-Y420-FYN [plasma membrane]
(R-HSA-1810410)
FYN [cytosol]
(R-HSA-200917)
0.556
3
UniProt:Q9NYP7 ELOVL5
1
ELOVL5 [endoplasmic reticulum membrane]
(R-HSA-548679)
0.556
3
UniProt:P05067 APP
20
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
UniProt:Q8IWU4 SLC30A8
2
SLC30A8 [Golgi membrane]
(R-HSA-9817561)
SLC30A8 [secretory granule membrane]
(R-HSA-437106)
0.556
3
UniProt:Q15125 EBP
1
EBP [endoplasmic reticulum membrane]
(R-HSA-195697)
0.556
3
UniProt:Q3SXY8 ARL13B
8
PolyUb-Misfolded ARL13B [lysosomal lumen]
(R-HSA-9660004)
PolyUb-Misfolded ARL13B [cytosol]
(R-HSA-9641129)
Ub-Misfolded ARL13B [cytosol]
(R-HSA-9641119)
Misfolded ARL13B [cytosol]
(R-HSA-9640110)
Misfolded ARL13B [cilium]
(R-HSA-9640116)
ARL13B [cilium]
(R-HSA-5618181)
PolyUb-Misfolded ARL13B [late endosome lumen]
(R-HSA-9659986)
ARL13B [plasma membrane]
(R-HSA-9716787)
0.556
3
UniProt:Q14032 BAAT
2
BAAT [cytosol]
(R-HSA-159392)
BAAT [peroxisomal matrix]
(R-HSA-193517)
0.556
3
UniProt:O95470 SGPL1
1
PXLP-SGPL1 [endoplasmic reticulum membrane]
(R-HSA-428661)
0.556
3
UniProt:P21579 SYT1
7
SYT1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869113)
SYT1 [clathrin-sculpted acetylcholine transport vesicle membrane]
(R-HSA-210536)
SYT1 [synaptic vesicle membrane]
(R-HSA-194789)
SYT1 [clathrin-sculpted glutamate transport vesicle membrane]
(R-HSA-372514)
SYT1 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-917741)
SYT1 [plasma membrane]
(R-HSA-168786)
SYT1 [clathrin-sculpted monoamine transport vesicle membrane]
(R-HSA-372508)
0.556
3
UniProt:Q9Y2X7 GIT1
2
GIT1 [cytosol]
(R-HSA-430326)
p-Y383-GIT1 [cytosol]
(R-HSA-3928463)
0.553
2
UniProt:Q16880 UGT8
1
UGT8 [endoplasmic reticulum membrane]
(R-HSA-9844570)
0.527
3
UniProt:P0DTC3 3a
9
O-glycosyl 3a [virion membrane]
(R-COV-9694395)
O-glycosyl 3a [endocytic vesicle membrane]
(R-COV-9694729)
O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694386)
GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9694658)
3a [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9694716)
3a [endoplasmic reticulum lumen]
(R-COV-9694584)
O-glycosyl 3a [endolysosome membrane]
(R-COV-9754541)
O-glycosyl 3a [plasma membrane]
(R-COV-9694433)
O-glycosyl 3a [extracellular region]
(R-COV-9694387)
0.527
2
UniProt:Q16581 C3AR1
3
C3AR1 [plasma membrane]
(R-HSA-444727)
C3AR1 [azurophil granule membrane]
(R-HSA-6799517)
C3AR1 [specific granule membrane]
(R-HSA-6799516)
0.527
2
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