Reactome | ACAA2 [mitochondrial matrix]

ACAA2 [mitochondrial matrix]

Stable Identifier

R-HSA-8874752

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

3-ketoacyl-CoA thiolase, mitochondrial ecNumber2.3.1.16/ecNumber, THIM_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P42765 ACAA2

Gene Names

ACAA2

Chain

chain:1-397, transit peptide:1-16

Reference Genes

BioGPS Gene:10449 ACAA2

COSMIC (genes):ACAA2 ACAA2

CTD Gene:10449 ACAA2

dbSNP Gene:10449 ACAA2

ENSEMBL:ENSG00000167315 ACAA2

HGNC:83 ACAA2

KEGG:hsa:10449 ACAA2

Monarch:10449 ACAA2

NCBI Gene:10449 ACAA2

OMIM:604770 ACAA2

UCSC:P42765 ACAA2

Reference Transcript

RefSeq:NM_006111.2 ACAA2

Other Identifiers

10449

11715767_s_at

16855184

202002_PM_at

202002_at

202003_PM_s_at

202003_s_at

241114_PM_s_at

241114_s_at

3807568

3807570

3807571

3807572

3807574

3807575

3807576

3807579

3807580

3807581

3807582

3807583

3807584

3807585

3807586

3807587

3807588

3807589

3807590

4007546

4007549

41530_at

8023261

91157_at

A_23_P89799

A_32_P80809

D16294_at

GE57098

GE86909

GO:0003723

GO:0003824

GO:0003985

GO:0003986

GO:0003988

GO:0005515

GO:0005739

GO:0005759

GO:0006629

GO:0006631

GO:0006635

GO:0006695

GO:0007005

GO:0016740

GO:0016746

GO:0016747

GO:0016787

GO:0043226

GO:0047617

GO:0061024

GO:0071456

GO:1901029

GO:1902109

HMNXSV003024424

Hs.146125.1.A1_3p_at

Hs.32500.0.A1_3p_at

ILMN_1660199

TC18000506.hg

g5174428_3p_a_at

Participates

as a component of

ACAA2 tetramer [mitochondrial matrix] (Homo sapiens)

Inferred To

acaa2 [mitochondrial matrix] (Danio rerio)

acaa2 [mitochondrial matrix] (Xenopus tropicalis)

acaa-2 [mitochondrial matrix] (Caenorhabditis elegans)

Acaa [mitochondrial matrix] (Drosophila melanogaster)

ACAA2 [mitochondrial matrix] (Bos taurus)

ACAA2 [mitochondrial matrix] (Canis familiaris)

ACAA2 [mitochondrial matrix] (Gallus gallus)

ACAA2 [mitochondrial matrix] (Mus musculus)

ACAA2 [mitochondrial matrix] (Rattus norvegicus)

ACAA2 [mitochondrial matrix] (Sus scrofa)

Cross References

ENSEMBL

ENSP00000285093, ENST00000285093

OpenTargets

ENSG00000167315

IntEnz

2.3.1.16, 3.1.2.1

HPA

ENSG00000167315-ACAA2

PRO

P42765

Pharos - Targets

P42765

GlyGen

P42765

HMDB Protein

HMDBP00031

PDB

4C2K, 4C2J

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15031 LARS2	1	LARS2(1-?) [mitochondrial matrix] (R-HSA-379635)	0.527	3
UniProt:P0DTC3 3a	9	O-glycosyl 3a [virion membrane] (R-COV-9694395) O-glycosyl 3a [endocytic vesicle membrane] (R-COV-9694729) O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694386) GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694658) 3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694716) 3a [endoplasmic reticulum lumen] (R-COV-9694584) O-glycosyl 3a [endolysosome membrane] (R-COV-9754541) O-glycosyl 3a [plasma membrane] (R-COV-9694433) O-glycosyl 3a [extracellular region] (R-COV-9694387)	0.482	2