Reactome | PROCR(18-?) [extracellular region]

PROCR(18-?) [extracellular region]

Stable Identifier

R-HSA-5610109

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Soluble endothelial protein C receptor, EPCR_HUMAN, sEPCR, Soluble activated protein C receptor

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UNN8 PROCR

Gene Names

PROCR, EPCR

Chain

signal peptide:1-17, chain:18-238

Reference Genes

BioGPS Gene:10544 PROCR

COSMIC (genes):PROCR PROCR

CTD Gene:10544 PROCR

dbSNP Gene:10544 PROCR

ENSEMBL:ENSG00000101000.6 PROCR

HGNC:9452 PROCR

KEGG Gene (Homo sapiens):10544 PROCR

Monarch:10544 PROCR

NCBI Gene:10544 PROCR

OMIM:600646 PROCR

UCSC:Q9UNN8 PROCR

Reference Transcript

RefSeq:NM_006404.4 PROCR

Other Identifiers

10544

11737798_a_at

16913065

203650_PM_at

203650_at

3883214

3883215

3883216

3883217

3883218

3883219

3883221

3883222

3883223

3883224

647_at

8062108

A_23_P80040

GE53679

GO:0005515

GO:0005576

GO:0005615

GO:0005813

GO:0005815

GO:0005856

GO:0005886

GO:0005925

GO:0007596

GO:0007599

GO:0009986

GO:0016020

GO:0038023

GO:0042060

GO:0043226

GO:0048471

GO:0050819

GO:0060089

GO:0070062

HMNXSV003004705

HMNXSV003022864

ILMN_1717262

L35545_at

PH_hs_0004716

PH_hs_0035477

TC20000248.hg

g5453645_3p_at

Participates

as a component of

as an input of

Other forms of this molecule

PROCR [plasma membrane]

Inferred To

Procr [extracellular region] (Mus musculus)

Procr [extracellular region] (Rattus norvegicus)

PROCR [extracellular region] (Bos taurus)

PROCR [extracellular region] (Gallus gallus)

PROCR [extracellular region] (Sus scrofa)

PROCR(18-?) [extracellular region] (Canis familiaris)

Cross References

RefSeq

NP_006395.2

OpenTargets

ENSG00000101000

GeneCards

Q9UNN8

HPA

ENSG00000101000-PROCR

Ensembl

ENST00000216968, ENSG00000101000, ENSP00000216968

PRO

Q9UNN8

Pharos - Targets

Q9UNN8

Orphanet

19825

PDB

4V3D, 7OKU, 1LQV, 6SNY, 1L8J, 7OKV, 7OKS, 7OKT, 4V3E, 3JTC, 7Q5D

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P25116 F2R	4	F2R(27-41) [extracellular region] (R-HSA-114586) pro-F2R [plasma membrane] (R-HSA-9708861) Activated F2R [plasma membrane] (R-HSA-114531) F2R(27-425) [plasma membrane] (R-HSA-61309)	0.641	5
UniProt:P0DTC3 3a	9	O-glycosyl 3a [virion membrane] (R-COV-9694395) O-glycosyl 3a [endocytic vesicle membrane] (R-COV-9694729) O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694386) GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694658) 3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694716) 3a [endoplasmic reticulum lumen] (R-COV-9694584) O-glycosyl 3a [endolysosome membrane] (R-COV-9754541) O-glycosyl 3a [plasma membrane] (R-COV-9694433) O-glycosyl 3a [extracellular region] (R-COV-9694387)	0.527	2

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