Reactome | RABGGTA [cytosol]

RABGGTA [cytosol]

Stable Identifier

R-HSA-8870418

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Geranylgeranyl transferase type-2 subunit alpha ecNumber2.5.1.60/ecNumber, PGTA_HUMAN

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External Reference Information

External Reference

UniProt:Q92696 RABGGTA

Gene Names

RABGGTA

Chain

chain:1-567

Reference Genes

BioGPS Gene:5875 RABGGTA

COSMIC (genes):RABGGTA RABGGTA

CTD Gene:5875 RABGGTA

dbSNP Gene:5875 RABGGTA

ENSEMBL:ENSG00000100949 RABGGTA

ENSEMBL_homo_sapiens_GENE:ENSG00000100949.15 RABGGTA

ENSEMBL_homo_sapiens_GENE:ENSG00000285193.1 RABGGTA

HGNC:9795 RABGGTA

KEGG Gene (Homo sapiens):5875 RABGGTA

Monarch:5875 RABGGTA

NCBI Gene:5875 RABGGTA

OMIM:601905 RABGGTA

UCSC:Q92696 RABGGTA

Reference Transcript

Other Identifiers

100_g_at

111_at

11721186_a_at

11737759_x_at

11751406_a_at

11755532_x_at

16791244

203573_PM_s_at

203573_s_at

3558073

3558074

3558075

3558077

3558081

3558082

3558084

3558085

3558087

3558090

3558092

3558093

3558094

3558097

3558098

3558100

3558101

3558102

3558105

3558106

3558107

3558108

5875

7978239

A_23_P54223

GE60249

GO:0003824

GO:0004659

GO:0004663

GO:0005515

GO:0005737

GO:0005829

GO:0005886

GO:0005968

GO:0007601

GO:0008270

GO:0008318

GO:0016740

GO:0018342

GO:0018344

GO:0031267

GO:0036211

GO:0050877

GO:0140096

HMNXSV003056029

ILMN_1770329

PH_hs_0032991

TC14000972.hg

Y08200_at

g4759015_3p_a_at

g4759015_3p_x_at

Participates

as an input of

RABGGTA and RABGGTB bind (Homo sapiens)

as a component of

Other forms of this molecule

RABGGTA [plasma membrane]

Inferred To

bet4 [cytosol] (Schizosaccharomyces pombe)

BET4 [cytosol] (Saccharomyces cerevisiae)

rabggta [cytosol] (Danio rerio)

rabggta [cytosol] (Dictyostelium discoideum)

rabggta [cytosol] (Xenopus tropicalis)

Rabggta [cytosol] (Mus musculus)

Rabggta [cytosol] (Rattus norvegicus)

Ghost homologue of RABGGTA [cytosol] (Gallus gallus)

RABGGTA [cytosol] (Bos taurus)

RABGGTA [cytosol] (Caenorhabditis elegans)

RABGGTA [cytosol] (Canis familiaris)

RABGGTA [cytosol] (Plasmodium falciparum)

RABGGTA [cytosol] (Sus scrofa)

RabGGTa [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_878256.1, NP_004572.3

OpenTargets

ENSG00000100949

GeneCards

Q92696

HPA

ENSG00000100949-RABGGTA

Ensembl

ENSP00000494636, ENSG00000285193, ENST00000646658, ENST00000399409, ENST00000216840, ENSP00000496595, ENSP00000216840, ENSP00000382341, ENST00000644383, ENSG00000100949

PRO

Q92696

Pharos - Targets

Q92696

HMDB Protein

HMDBP11878

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53611 RABGGTB	2	RABGGTB [plasma membrane] (R-HSA-6801098) RABGGTB [cytosol] (R-HSA-8870419)	0.8	8
UniProt:P24386 CHM	1	CHM [cytosol] (R-HSA-6801097)	0.744	6
UniProt:P20339 RAB5A	7	GGC-RAB5A [clathrin-coated endocytic vesicle membrane] (R-HSA-8871125) GGC-RAB5A [early endosome membrane] (R-HSA-8875323) GGC-RAB5A [cytosol] (R-HSA-8870432) RAB5A [early endosome membrane] (R-HSA-2130175) RAB5A [cytosol] (R-HSA-2201187) GGC-RAB5A [macropinosome membrane] (R-HSA-9837697) RAB5A [endosome membrane] (R-HSA-452257)	0.671	5
UniProt:P26374 CHML	1	CHML [cytosol] (R-HSA-8870443)	0.643	4
UniProt:Q15771 RAB30	3	RAB30 [cytosol] (R-HSA-8873677) GGC-RAB30 [cytosol] (R-HSA-8873972) RAB30 [Golgi membrane] (R-HSA-8849598)	0.527	2
UniProt:Q9H0U4 RAB1B	8	p-T191-RAB1B [Golgi membrane] (R-HSA-2422374) RAB1B [Golgi membrane] (R-HSA-2422381) RAB1B [cytosol] (R-HSA-5685727) RAB1B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-6807768) RAB1B [transport vesicle] (R-HSA-6808799) GGC-RAB1B [cytosol] (R-HSA-8870426) GGC-RAB1B [transport vesicle membrane] (R-HSA-8877470) RAB1B [endoplasmic reticulum membrane] (R-HSA-6810977)	0.527	3
UniProt:P62820 RAB1A	8	RAB1A [endoplasmic reticulum membrane] (R-HSA-6810974) GGC-RAB1A [transport vesicle membrane] (R-HSA-8877472) GGC-RAB1A [cytosol] (R-HSA-8870424) RAB1A [transport vesicle] (R-HSA-6808796) RAB1A [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-6807766) p-T195-RAB1A [Golgi membrane] (R-HSA-2172190) RAB1A [Golgi membrane] (R-HSA-2167938) RAB1A [cytosol] (R-HSA-5685725)	0.527	2
UniProt:Q96AH8 RAB7B	4	RAB7B [late endosome membrane] (R-HSA-8854158) GGC-RAB7B [lysosomal membrane] (R-HSA-8877450) GGC-RAB7B [cytosol] (R-HSA-8874059) RAB7B [cytosol] (R-HSA-8873707)	0.527	3
UniProt:A1L0T0 HACL2			0.527	4
UniProt:Q13637 RAB32	3	GGC-RAB32 [melanosome membrane] (R-HSA-8877737) GGC-RAB32 [cytosol] (R-HSA-8873980) RAB32 [cytosol] (R-HSA-8873696)	0.527	4
UniProt:P04406 GAPDH	1	GAPDH [cytosol] (R-HSA-70428)	0.527	2
UniProt:Q9UQV4 LAMP3			0.527	2
UniProt:Q9NP90 RAB9B	7	RAB9B [transport vesicle] (R-HSA-6814621) RAB9B [trans-Golgi network membrane] (R-HSA-6814620) GGC-RAB9B [trans-Golgi network membrane] (R-HSA-8876089) GGC-RAB9B [cytosol] (R-HSA-8874076) RAB9B [cytosol] (R-HSA-6813907) RAB9B [plasma membrane] (R-HSA-6804810) RAB9B [secretory granule membrane] (R-HSA-6804773)	0.527	4
UniProt:O14966 RAB29	2	GGC-RAB29 [cytosol] (R-HSA-8873957) RAB29 [cytosol] (R-HSA-8873713)	0.527	3
UniProt:P51151 RAB9A	5	RAB9A [transport vesicle] (R-HSA-6814618) RAB9A [trans-Golgi network membrane] (R-HSA-6814616) GGC-RAB9A [trans-Golgi network membrane] (R-HSA-8876087) GGC-RAB9A [cytosol] (R-HSA-8874069) RAB9A [cytosol] (R-HSA-6813904)	0.527	3
UniProt:Q9BVM2 DPCD			0.527	2
UniProt:Q13636 RAB31	5	GGC-RAB31 [early endosome membrane] (R-HSA-8877278) GGC-RAB31 [cytosol] (R-HSA-8873974) RAB31 [cytosol] (R-HSA-8873690) RAB31 [plasma membrane] (R-HSA-6804813) RAB31 [secretory granule membrane] (R-HSA-6804797)	0.527	3
UniProt:O15498 YKT6	5	PalmC-YKT6 [ER to Golgi transport vesicle membrane] (R-HSA-5688557) PalmC-YKT6 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688558) PalmC-YKT6 [endoplasmic reticulum membrane] (R-HSA-5688145) PalmC-YKT6 [transport vesicle] (R-HSA-6808794) PalmC-YKT6 [Golgi membrane] (R-HSA-6808792)	0.527	3
UniProt:Q9NRW1 RAB6B	6	RAB6B [endoplasmic reticulum membrane] (R-HSA-8849252) RAB6B [trans-Golgi network membrane] (R-HSA-6810985) RAB6B [Golgi membrane] (R-HSA-8849249) GGC-RAB6B [trans-Golgi network membrane] (R-HSA-8876081) GGC-RAB6B [cytosol] (R-HSA-8874055) RAB6B [cytosol] (R-HSA-6810983)	0.527	3

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