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PalmC-YKT6 [Golgi membrane]
Stable Identifier
R-HSA-6808792
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
COPI vesicle uncoating (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
cis-SNARE:3xSNAP:NSF hexamer [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
cis-Golgi cis-SNARE binds NSF and SNAPs (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
cis-SNARE:3xSNAP:NSF hexamer [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
COPI vesicle uncoating (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
cis-SNARE:3xSNAP:NSF hexamer [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
cis-Golgi cis-SNARE binds NSF and SNAPs (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
cis-SNARE:3xSNAP:NSF hexamer [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Intra-Golgi traffic (Homo sapiens)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L:GOSR1:NSF hexamer:3xSNAPs [Golgi membrane] (Homo sapiens)
STX:PalmC-YKT6:BET1L:GOSR1 [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
Formation of cis-SNARE complex and membrane fusion in intra-Golgi retrograde traffic (Homo sapiens)
COG complex:CUX1 dimer:GOLGA5 dimer:STX5:PalmC-YKT6:BET1L:GOSR1:intra-Golgi retrograde cargo [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
STX:PalmC-YKT6:BET1L:GOSR1 [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
NSF and SNAPs bind the cis-SNARE at the Golgi (Homo sapiens)
STX5:PalmC-YKT6:BET1L:GOSR1:NSF hexamer:3xSNAPs [Golgi membrane] (Homo sapiens)
STX:PalmC-YKT6:BET1L:GOSR1 [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
STX:PalmC-YKT6:BET1L:GOSR1 [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
The COG complex and CUX1 and GOLGA5 dimers contribute to intra-Golgi vesicle tethering (Homo sapiens)
COG complex:CUX1 dimer:GOLGA5 dimer:STX5:PalmC-YKT6:BET1L:GOSR1:intra-Golgi retrograde cargo [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
PalmC-YKT6 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15498 YKT6
Gene Names
YKT6
Chain
chain:1-195, propeptide:196-198
Reference Genes
BioGPS Gene:10652 YKT6
COSMIC (genes):YKT6 YKT6
CTD Gene:10652 YKT6
dbSNP Gene:10652 YKT6
ENSEMBL:ENSG00000106636.9 YKT6
HGNC:16959 YKT6
KEGG Gene (Homo sapiens):10652 YKT6
Monarch:10652 YKT6
NCBI Gene:10652 YKT6
OMIM:606209 YKT6
UCSC:O15498 YKT6
Reference Transcript
RefSeq:NM_006555.3 YKT6
RefSeq:XM_017011682.1 YKT6
Other Identifiers
10652
11718980_a_at
11747440_a_at
11757597_a_at
17045656
217784_PM_at
217784_at
217785_PM_s_at
217785_s_at
2981995
2999817
2999818
2999819
2999820
2999821
2999822
2999826
2999830
2999831
2999832
2999833
2999834
2999835
2999836
41516_at
41517_g_at
45313_at
8132580
A_14_P117216
A_23_P134527
A_24_P372048
GE59597
GO:0000139
GO:0003824
GO:0005484
GO:0005515
GO:0005737
GO:0005739
GO:0005768
GO:0005783
GO:0005794
GO:0005829
GO:0005886
GO:0006888
GO:0006903
GO:0006904
GO:0012505
GO:0015031
GO:0016020
GO:0016192
GO:0016740
GO:0019706
GO:0030133
GO:0030659
GO:0031201
GO:0031410
GO:0033116
GO:0042147
GO:0043025
GO:0043226
GO:0043231
GO:0045296
GO:0060090
GO:0061024
GO:0061025
GO:0097440
GO:0097441
GO:0140096
HMNXSV003010034
HMNXSV003057202
Hs.296244.0.S2_3p_at
Hs.296244.0.S2_3p_x_at
ILMN_1695998
PH_hs_0039621
TC07000274.hg
g5730119_3p_a_at
Participates
as an output of
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Homo sapiens)
NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Homo sapiens)
as a component of
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
Other forms of this molecule
PalmC-YKT6 [transport vesicle]
PalmC-YKT6 [endoplasmic reticulum-Golgi intermediate compartment membrane]
PalmC-YKT6 [endoplasmic reticulum membrane]
PalmC-YKT6 [ER to Golgi transport vesicle membrane]
Inferred To
ykt6 [Golgi membrane]
(Danio rerio)
ykt6 [Golgi membrane]
(Schizosaccharomyces pombe)
ykt6 [Golgi membrane]
(Xenopus tropicalis)
ykt-6 [Golgi membrane]
(Caenorhabditis elegans)
Ykt6 [Golgi membrane]
(Drosophila melanogaster)
Ykt6 [Golgi membrane]
(Mus musculus)
Ykt6 [Golgi membrane]
(Rattus norvegicus)
PalmC-YKT6 [Golgi membrane]
(Canis familiaris)
PalmC-YKT6 [Golgi membrane]
(Dictyostelium discoideum)
PalmC-YKT6 [Golgi membrane]
(Plasmodium falciparum)
PalmC-YKT6 [Golgi membrane]
(Sus scrofa)
YKT6 [Golgi membrane]
(Bos taurus)
YKT6 [Golgi membrane]
(Gallus gallus)
YKT6 [Golgi membrane]
(Saccharomyces cerevisiae)
Modified Residues
Name
S-palmitoyl-L-cysteine at 194
Coordinate
194
PsiMod Name
S-palmitoyl-L-cysteine [MOD:00115]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.
Cross References
RefSeq
XP_016867171.1
,
NP_006546.1
OpenTargets
ENSG00000106636
GeneCards
O15498
HPA
ENSG00000106636-YKT6
Ensembl
ENST00000679020
,
ENSP00000223369
,
ENST00000496112
,
ENSG00000106636
,
ENSP00000504623
,
ENST00000223369
,
ENSP00000420805
PRO
O15498
Pharos - Targets
O15498
PDB
6J7F
,
6J74
,
6J7X
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