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GGC-RAB7B [cytosol]
Stable Identifier
R-HSA-8874059
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ras-related protein Rab-7b, RAB7B_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
RAB geranylgeranylation (Homo sapiens)
RGGT geranylgeranylates RAB proteins (Homo sapiens)
CHMs:GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs [cytosol] (Homo sapiens)
GGC-RAB7B [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
MON1:CCZ1 exchanges GTP for GDP on RAB7 (Homo sapiens)
GGC-RAB7:GDP:GDIs,CHMs [cytosol] (Homo sapiens)
GGC-RAB7:GDP [cytosol] (Homo sapiens)
GGC-RAB7 [cytosol] (Homo sapiens)
GGC-RAB7B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96AH8 RAB7B
Gene Names
RAB7B
Chain
chain:1-199
Reference Genes
BioGPS Gene:338382 RAB7B
CTD Gene:338382 RAB7B
dbSNP Gene:338382 RAB7B
ENSEMBL:ENSG00000276600 RAB7B
HGNC:30513 RAB7B
Monarch:338382 RAB7B
NCBI Gene:338382 RAB7B
UCSC:Q96AH8 RAB7B
Reference Transcript
RefSeq:NM_177403.5 RAB7B
RefSeq:NM_001164522.2 RAB7B
Other Identifiers
11725570_a_at
11754764_a_at
1553982_PM_a_at
1553982_a_at
17126286
17126288
230266_PM_at
230266_at
338382
4057777
4065397
4112424
4121470
46105_at
78918_at
8180340
82456_at
91241_at
ADDON002889.hg
ADDON002890.hg
A_23_P252541
A_23_P61590
A_23_P84281
GE589512
GE83512
GE88302
GO:0000166
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005764
GO:0005768
GO:0005770
GO:0005773
GO:0005794
GO:0005802
GO:0006355
GO:0008333
GO:0015031
GO:0016020
GO:0016192
GO:0016787
GO:0030670
GO:0031410
GO:0031902
GO:0032755
GO:0034144
GO:0034164
GO:0034499
GO:0043226
GO:0045335
GO:0045654
GO:0051092
GO:0061024
GO:0071346
GO:0090385
HMNXSV003008901
HMNXSV003030422
Hs.55405.0.A1_3p_at
Hs2.135717.1.S1_3p_s_at
ILMN_1771688
PH_hs_0031254
Participates
as a candidate of
GGC-RAB7 [cytosol] (Homo sapiens)
GGC-RABs [cytosol] (Homo sapiens)
Other forms of this molecule
RAB7B [late endosome membrane]
GGC-RAB7B [lysosomal membrane]
RAB7B [cytosol]
Inferred To
GGC-RAB7B [cytosol]
(Bos taurus)
GGC-RAB7B [cytosol]
(Dictyostelium discoideum)
GGC-RAB7B [cytosol]
(Drosophila melanogaster)
GGC-RAB7B [cytosol]
(Gallus gallus)
GGC-RAB7B [cytosol]
(Mus musculus)
GGC-RAB7B [cytosol]
(Plasmodium falciparum)
GGC-RAB7B [cytosol]
(Saccharomyces cerevisiae)
GGC-RAB7B [cytosol]
(Schizosaccharomyces pombe)
GGC-RAB7B [cytosol]
(Sus scrofa)
Homologues of GGC-RAB7B [cytosol]
(Dictyostelium discoideum)
Homologues of GGC-RAB7B [cytosol]
(Schizosaccharomyces pombe)
rab-7 [cytosol]
(Caenorhabditis elegans)
Rab7b [cytosol]
(Rattus norvegicus)
RAB7B [cytosol]
(Canis familiaris)
Modified Residues
Name
S-geranylgeranyl-L-cysteine at 198
Coordinate
198
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Name
S-geranylgeranyl-L-cysteine at 199
Coordinate
199
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Cross References
ENSEMBL
ENSP00000482499
,
ENST00000623597
,
ENSP00000485468
,
ENST00000617991
,
ENST00000617070
,
ENSP00000479762
OpenTargets
ENSG00000276600
HPA
ENSG00000276600-RAB7B
PRO
Q96AH8
Pharos - Targets
Q96AH8
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q92696 RABGGTA
2
RABGGTA [plasma membrane]
(R-HSA-6801086)
RABGGTA [cytosol]
(R-HSA-8870418)
0.527
3
UniProt:P53611 RABGGTB
2
RABGGTB [plasma membrane]
(R-HSA-6801098)
RABGGTB [cytosol]
(R-HSA-8870419)
0.527
2
UniProt:P24386 CHM
1
CHM [cytosol]
(R-HSA-6801097)
0.527
3
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