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GGC-RAB1B [cytosol]
Stable Identifier
R-HSA-8870426
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ras-related protein Rab-1B
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
RAB geranylgeranylation (Homo sapiens)
RGGT geranylgeranylates RAB proteins (Homo sapiens)
CHMs:GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs [cytosol] (Homo sapiens)
GGC-RAB1B [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
TRAPPC complexes exchange GTP for GDP on RAB1 (Homo sapiens)
GGC-RAB1:GDP:GDIs,CHMs [cytosol] (Homo sapiens)
GGC-RAB1:GDP [cytosol] (Homo sapiens)
GGC-RAB1B:GDP [cytosol] (Homo sapiens)
GGC-RAB1B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H0U4 RAB1B
Gene Names
RAB1B
Chain
chain:1-201
Reference Genes
BioGPS Gene:81876 RAB1B
COSMIC (genes):RAB1B RAB1B
CTD Gene:81876 RAB1B
dbSNP Gene:81876 RAB1B
ENSEMBL:ENSG00000174903 RAB1B
ENSEMBL_homo_sapiens_GENE:ENSG00000174903.16 RAB1B
HGNC:18370 RAB1B
KEGG Gene (Homo sapiens):81876 RAB1B
Monarch:81876 RAB1B
NCBI Gene:81876 RAB1B
OMIM:612565 RAB1B
UCSC:Q9H0U4 RAB1B
Reference Transcript
RefSeq:NM_030981.2 RAB1B
Other Identifiers
11716668_at
11716669_x_at
11716670_s_at
16727351
220964_PM_s_at
220964_s_at
3205561
3205562
3205563
3205564
3205565
3205568
3336075
3336080
3336081
3336082
3336085
3336086
3336087
3336088
3336089
3336090
3336091
3336092
3336093
3336095
3336096
43390_s_at
65902_at
65903_at
7941583
81876
A_33_P3329607
GE61198
GO:0000045
GO:0000139
GO:0000166
GO:0003824
GO:0003924
GO:0003925
GO:0005515
GO:0005525
GO:0005576
GO:0005615
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0006886
GO:0006888
GO:0006914
GO:0007030
GO:0012505
GO:0015031
GO:0016020
GO:0016192
GO:0016787
GO:0019068
GO:0030133
GO:0031410
GO:0033116
GO:0034045
GO:0043226
GO:0048471
GO:0070062
GO:0098772
GO:1901135
GO:1903020
GO:2000785
HMNXSV003029388
ILMN_1664030
ILMN_1762802
PH_hs_0015483
PH_hs_0038055
TC11000657.hg
g13569961_3p_s_at
Participates
as a component of
GGC-RAB1B:GDP [cytosol] (Homo sapiens)
as a member of
GGC-RABs [cytosol] (Homo sapiens)
Other forms of this molecule
p-T191-RAB1B [Golgi membrane]
RAB1B [Golgi membrane]
RAB1B [cytosol]
RAB1B [endoplasmic reticulum-Golgi intermediate compartment membrane]
RAB1B [transport vesicle]
GGC-RAB1B [transport vesicle membrane]
RAB1B [endoplasmic reticulum membrane]
Inferred To
GGC-RAB1B [cytosol]
(Canis familiaris)
GGC-RAB1B [cytosol]
(Danio rerio)
GGC-RAB1B [cytosol]
(Dictyostelium discoideum)
GGC-RAB1B [cytosol]
(Mus musculus)
GGC-RAB1B [cytosol]
(Plasmodium falciparum)
GGC-RAB1B [cytosol]
(Rattus norvegicus)
GGC-RAB1B [cytosol]
(Saccharomyces cerevisiae)
GGC-RAB1B [cytosol]
(Schizosaccharomyces pombe)
rabW [cytosol]
(Dictyostelium discoideum)
rab-1 [cytosol]
(Caenorhabditis elegans)
rab1ab [cytosol]
(Danio rerio)
rsmM [cytosol]
(Dictyostelium discoideum)
Rab1 [cytosol]
(Drosophila melanogaster)
rab1E [cytosol]
(Dictyostelium discoideum)
Homologues of GGC-RAB1B [cytosol]
(Danio rerio)
Homologues of GGC-RAB1B [cytosol]
(Dictyostelium discoideum)
Homologues of GGC-RAB1B [cytosol]
(Drosophila melanogaster)
Homologues of GGC-RAB1B [cytosol]
(Saccharomyces cerevisiae)
rab1bb [cytosol]
(Danio rerio)
RabX6 [cytosol]
(Drosophila melanogaster)
rab1ba [cytosol]
(Danio rerio)
RAB1B [cytosol]
(Bos taurus)
Modified Residues
Name
S-geranylgeranyl-L-cysteine at 200
Coordinate
200
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Name
S-geranylgeranyl-L-cysteine at 201
Coordinate
201
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Cross References
RefSeq
NP_112243.1
OpenTargets
ENSG00000174903
HPA
ENSG00000174903-RAB1B
GeneCards
Q9H0U4
Ensembl
ENSP00000310226
,
ENSG00000174903
,
ENST00000311481
PRO
Q9H0U4
Pharos - Targets
Q9H0U4
HMDB Protein
HMDBP08509
PDB
5SZK
,
4HLQ
,
3JZA
,
5SZH
,
8ALK
,
3NKV
,
5O74
,
6SKU
,
4I1O
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.59
5
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.547
2
UniProt:P10636-8 MAPT
3
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
MAPT-8 [cytosol]
(R-HSA-9619519)
0.527
5
UniProt:P24386 CHM
1
CHM [cytosol]
(R-HSA-6801097)
0.527
3
UniProt:Q92696 RABGGTA
2
RABGGTA [plasma membrane]
(R-HSA-6801086)
RABGGTA [cytosol]
(R-HSA-8870418)
0.527
3
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