Reactome | CHML [cytosol]

CHML [cytosol]

Stable Identifier

R-HSA-8870443

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Rab proteins geranylgeranyltransferase component A 2, RAE2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P26374 CHML

Gene Names

CHML, REP2

Chain

chain:1-656

Reference Genes

BioGPS Gene:1122 CHML

COSMIC (genes):CHML CHML

CTD Gene:1122 CHML

dbSNP Gene:1122 CHML

ENSEMBL:ENSG00000203668 CHML

HGNC:1941 CHML

Monarch:1122 CHML

NCBI Gene:1122 CHML

OMIM:118825 CHML

UCSC:P26374 CHML

Reference Transcript

RefSeq:NM_001821.3 CHML

Other Identifiers

1122

11722932_at

11722933_at

11722934_s_at

11722935_x_at

1565951_3p_s_at

1565951_PM_s_at

1565951_s_at

16701106

206079_PM_at

206079_at

226350_PM_at

226350_at

23596

2463505

2463506

2463507

2463508

2463509

2463510

2463511

2463512

2463516

2463517

2463518

2463519

2463520

2463521

2463522

2463523

32278_at

44026_at

63525_at

7925500

A_23_P46118

A_24_P712350

GE55659

GE59909

GO:0004930

GO:0005092

GO:0005096

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005968

GO:0006886

GO:0007186

GO:0007264

GO:0016020

GO:0016192

GO:0018344

GO:0031267

GO:0043226

GO:0060089

GO:0098772

HMNXSV003038946

Hs.28661.0.S1_3p_at

Hs2.436389.1.S1_3p_s_at

ILMN_1747697

ILMN_2382717

PH_hs_0034840

TC01004027.hg

TC01006233.hg

X64728_at

g4502810_3p_at

Participates

as a member of

Inferred To

MRS6 [cytosol] (Saccharomyces cerevisiae)

chm [cytosol] (Danio rerio)

chm [cytosol] (Xenopus tropicalis)

CHML [cytosol] (Bos taurus)

CHML [cytosol] (Canis familiaris)

CHML [cytosol] (Dictyostelium discoideum)

CHML [cytosol] (Gallus gallus)

CHML [cytosol] (Plasmodium falciparum)

CHML [cytosol] (Schizosaccharomyces pombe)

CHML [cytosol] (Sus scrofa)

Chml [cytosol] (Mus musculus)

Chml [cytosol] (Rattus norvegicus)

Rep [cytosol] (Drosophila melanogaster)

rep-1 [cytosol] (Caenorhabditis elegans)

Cross References

ENSEMBL

ENSP00000355511, ENST00000366553

OpenTargets

ENSG00000203668

HPA

ENSG00000203668-CHML

PRO

P26374

Pharos - Targets

P26374

GlyGen

P26374

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P20339 RAB5A	7	RAB5A [cytosol] (R-HSA-2201187) GGC-RAB5A [macropinosome membrane] (R-HSA-9837697) RAB5A [endosome membrane] (R-HSA-452257) RAB5A [early endosome membrane] (R-HSA-2130175) GGC-RAB5A [cytosol] (R-HSA-8870432) GGC-RAB5A [early endosome membrane] (R-HSA-8875323) GGC-RAB5A [clathrin-coated endocytic vesicle membrane] (R-HSA-8871125)	0.671	5
UniProt:Q92696 RABGGTA	2	RABGGTA [plasma membrane] (R-HSA-6801086) RABGGTA [cytosol] (R-HSA-8870418)	0.643	4
UniProt:P20336 RAB3A	9	RAB3A [clathrin-sculpted monoamine transport vesicle membrane] (R-HSA-372512) RAB3A [plasma membrane] (R-HSA-210461) RAB3A [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-917743) RAB3A [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-210466) RAB3A [secretory granule membrane] (R-HSA-6804968) RAB3A [clathrin-sculpted acetylcholine transport vesicle membrane] (R-HSA-379365) RAB3A [cytosol] (R-HSA-8870410) GGC-RAB3A [cytosol] (R-HSA-8870429) GGC-RAB3A [secretory granule membrane] (R-HSA-8875319)	0.527	3

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