Reactome | PalmC-YKT6 [endoplasmic reticulum membrane]

PalmC-YKT6 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-5688145

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - ER to Golgi Anterograde Transport (Homo sapiens)
        
        COPII-mediated vesicle transport (Homo sapiens)
        
        SEC31:SEC13 and v-SNARE recruitment (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        ER-to-ERGIC v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        PalmC-YKT6 [endoplasmic reticulum membrane] (Homo sapiens)
        
        ER-to-ERGIC v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        PalmC-YKT6 [endoplasmic reticulum membrane] (Homo sapiens)
        
        Vesicle budding (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        ER-to-ERGIC v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        PalmC-YKT6 [endoplasmic reticulum membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:O15498 YKT6

Gene Names

YKT6

Chain

chain:1-195, propeptide:196-198

Reference Genes

BioGPS Gene:10652 YKT6

COSMIC (genes):YKT6 YKT6

CTD Gene:10652 YKT6

dbSNP Gene:10652 YKT6

ENSEMBL:ENSG00000106636 YKT6

ENSEMBL_homo_sapiens_GENE:ENSG00000106636.9 YKT6

HGNC:16959 YKT6

KEGG Gene (Homo sapiens):10652 YKT6

Monarch:10652 YKT6

NCBI Gene:10652 YKT6

OMIM:606209 YKT6

UCSC:O15498 YKT6

Reference Transcript

Other Identifiers

10652

11718980_a_at

11747440_a_at

11757597_a_at

17045656

217784_PM_at

217784_at

217785_PM_s_at

217785_s_at

2981995

2999817

2999818

2999819

2999820

2999821

2999822

2999826

2999830

2999831

2999832

2999833

2999834

2999835

2999836

41516_at

41517_g_at

45313_at

8132580

A_14_P117216

A_23_P134527

A_24_P372048

GE59597

GO:0000139

GO:0003824

GO:0005484

GO:0005515

GO:0005737

GO:0005739

GO:0005768

GO:0005783

GO:0005794

GO:0005829

GO:0005886

GO:0006888

GO:0006903

GO:0006904

GO:0015031

GO:0016020

GO:0016192

GO:0016740

GO:0019706

GO:0030133

GO:0030659

GO:0031201

GO:0031410

GO:0033116

GO:0042147

GO:0043025

GO:0043226

GO:0045296

GO:0060090

GO:0061024

GO:0061025

GO:0097440

GO:0097441

GO:0140096

HMNXSV003010034

HMNXSV003057202

Hs.296244.0.S2_3p_at

Hs.296244.0.S2_3p_x_at

ILMN_1695998

PH_hs_0039621

TC07000274.hg

g5730119_3p_a_at

Participates

as a candidate of

Other forms of this molecule

PalmC-YKT6 [ER to Golgi transport vesicle membrane]

PalmC-YKT6 [endoplasmic reticulum-Golgi intermediate compartment membrane]

PalmC-YKT6 [transport vesicle]

PalmC-YKT6 [Golgi membrane]

Inferred To

PalmC-YKT6 [endoplasmic reticulum membrane] (Dictyostelium discoideum)

PalmC-YKT6 [endoplasmic reticulum membrane] (Plasmodium falciparum)

ykt6 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

ykt6 [endoplasmic reticulum membrane] (Xenopus tropicalis)

ykt-6 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

YKT6 [endoplasmic reticulum membrane] (Bos taurus)

YKT6 [endoplasmic reticulum membrane] (Canis familiaris)

YKT6 [endoplasmic reticulum membrane] (Gallus gallus)

YKT6 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

YKT6 [endoplasmic reticulum membrane] (Sus scrofa)

Ykt6 [endoplasmic reticulum membrane] (Drosophila melanogaster)

Ykt6 [endoplasmic reticulum membrane] (Mus musculus)

Ykt6 [endoplasmic reticulum membrane] (Rattus norvegicus)

Modified Residues

Name

S-palmitoyl-L-cysteine at 194

Coordinate

194

PsiMod Name

S-palmitoyl-L-cysteine [MOD:00115]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.

Cross References

RefSeq

NP_006546.1, XP_016867171.1

OpenTargets

ENSG00000106636

HPA

ENSG00000106636-YKT6

GeneCards

O15498

Ensembl

ENSP00000504623, ENST00000223369, ENST00000496112, ENSG00000106636, ENSP00000223369, ENSP00000420805, ENST00000679020

PRO

O15498

Pharos - Targets

O15498

PDB

6J7X, 6J74, 6J7F

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O15155 BET1	3	BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688142) BET1 [transport vesicle] (R-HSA-6808719) BET1 [Golgi membrane] (R-HSA-6807743)	0.569	4
UniProt:O15400 STX7			0.564	4
UniProt:P59536 TAS2R41	1	TAS2R41 [plasma membrane] (R-HSA-3299622)	0.527	2
UniProt:O75558 STX11			0.527	2
UniProt:Q7Z6K3 PTAR1			0.527	3
UniProt:O75973 C1QRF			0.527	2
UniProt:P49356 FNTB	1	FNTB [cytosol] (R-HSA-2530482)	0.527	3
UniProt:Q92696 RABGGTA	2	RABGGTA [plasma membrane] (R-HSA-6801086) RABGGTA [cytosol] (R-HSA-8870418)	0.527	3
UniProt:P53611 RABGGTB	2	RABGGTB [plasma membrane] (R-HSA-6801098) RABGGTB [cytosol] (R-HSA-8870419)	0.527	3
UniProt:Q13190 STX5	5	STX5 [endoplasmic reticulum membrane] (R-HSA-5689474) STX5 [ER to Golgi transport vesicle membrane] (R-HSA-5689838) STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688157) STX5 [Golgi membrane] (R-HSA-6807771) STX5 [cytosol] (R-HSA-9613991)	0.527	2
UniProt:P54920 NAPA	1	NAPA [cytosol] (R-HSA-264469)	0.527	2
UniProt:Q8N6S5 AR6P6			0.527	2
UniProt:Q9UGM1 CHRNA9	1	CHRNA9 [plasma membrane] (R-HSA-507827)	0.527	2
UniProt:Q86Y82 STX12			0.527	3