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GGC-RAB32 [cytosol]
Stable Identifier
R-HSA-8873980
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ras-related protein Rab-32, RAB32_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
RAB geranylgeranylation (Homo sapiens)
RGGT geranylgeranylates RAB proteins (Homo sapiens)
CHMs:GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs [cytosol] (Homo sapiens)
GGC-RAB32 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Homo sapiens)
RAB32,RAB38:GDP:GDIs,CHMs [cytosol] (Homo sapiens)
RAB32,RAB38:GDP [cytosol] (Homo sapiens)
RAB32,RAB38 [cytosol] (Homo sapiens)
GGC-RAB32 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13637 RAB32
Gene Names
RAB32
Chain
initiator methionine:, chain:2-225
Reference Genes
BioGPS Gene:10981 RAB32
COSMIC (genes):RAB32 RAB32
CTD Gene:10981 RAB32
dbSNP Gene:10981 RAB32
ENSEMBL:ENSG00000118508 RAB32
ENSEMBL_homo_sapiens_GENE:ENSG00000118508.5 RAB32
HGNC:9772 RAB32
KEGG Gene (Homo sapiens):10981 RAB32
Monarch:10981 RAB32
NCBI Gene:10981 RAB32
OMIM:612906 RAB32
UCSC:Q13637 RAB32
Reference Transcript
RefSeq:NM_006834.4 RAB32
Other Identifiers
10981
11719411_at
17013404
204214_PM_s_at
204214_s_at
2929708
2929709
2929716
2929718
2929719
2929720
41523_at
8122554
A_14_P103113
A_23_P42375
A_24_P303480
GE59269
GO:0000166
GO:0002376
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005737
GO:0005739
GO:0005741
GO:0005768
GO:0005769
GO:0005783
GO:0005794
GO:0005802
GO:0005829
GO:0006886
GO:0007005
GO:0012505
GO:0016020
GO:0016192
GO:0016787
GO:0019882
GO:0030154
GO:0030670
GO:0030742
GO:0031410
GO:0031982
GO:0032438
GO:0033162
GO:0035646
GO:0035650
GO:0035651
GO:0036461
GO:0042470
GO:0043226
GO:0043231
GO:0044233
GO:0045335
GO:0072657
GO:0090382
GO:1903232
HMNXSV003012868
ILMN_2115434
PH_hs_0002729
TC06001065.hg
U59878_at
g5803132_3p_at
Participates
as a member of
RAB32,RAB38 [cytosol] (Homo sapiens)
as a candidate of
GGC-RABs [cytosol] (Homo sapiens)
Other forms of this molecule
GGC-RAB32 [melanosome membrane]
RAB32 [cytosol]
Inferred To
RAB32 [cytosol]
(Bos taurus)
RAB32 [cytosol]
(Gallus gallus)
glo-1 [cytosol]
(Caenorhabditis elegans)
rab32a [cytosol]
(Danio rerio)
GGC-RAB32 [cytosol]
(Dictyostelium discoideum)
GGC-RAB32 [cytosol]
(Mus musculus)
GGC-RAB32 [cytosol]
(Saccharomyces cerevisiae)
Rab32 [cytosol]
(Drosophila melanogaster)
Modified Residues
Name
S-geranylgeranyl-L-cysteine at 224
Coordinate
224
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Name
S-geranylgeranyl-L-cysteine at 225
Coordinate
225
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Cross References
RefSeq
NP_006825.1
Guide to Pharmacology - Targets
3292
OpenTargets
ENSG00000118508
HPA
ENSG00000118508-RAB32
GeneCards
Q13637
Ensembl
ENSG00000118508
,
ENST00000367495
,
ENSP00000356465
PRO
Q13637
Pharos - Targets
Q13637
PDB
4CYM
,
5OED
,
5OEC
,
4CZ2
,
6FF8
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.753
12
GTP [ChEBI:15996]
7
GTP [cilium]
(R-ALL-5617813)
GTP [early endosome membrane]
(R-ALL-2130170)
GTP [lysosomal membrane]
(R-ALL-2213216)
GTP [platelet dense granule lumen]
(R-ALL-114625)
GTP [cytoplasmic vesicle membrane]
(R-ALL-1996291)
GTP [ER to Golgi transport vesicle membrane]
(R-ALL-983318)
GTP [Golgi membrane]
(R-ALL-1806221)
0.544
2
UniProt:Q92696 RABGGTA
2
RABGGTA [plasma membrane]
(R-HSA-6801086)
RABGGTA [cytosol]
(R-HSA-8870418)
0.527
4
UniProt:P24386 CHM
1
CHM [cytosol]
(R-HSA-6801097)
0.527
4
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