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GGC-RAB1B [transport vesicle membrane]
Stable Identifier
R-HSA-8877470
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
transport vesicle membrane
Synonyms
Ras-related protein Rab-1B
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
TRAPPC complexes exchange GTP for GDP on RAB1 (Homo sapiens)
GGC-RAB1:GTP [transport vesicle membrane] (Homo sapiens)
GGC-RAB1B:GTP [transport vesicle membrane] (Homo sapiens)
GGC-RAB1B [transport vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H0U4 RAB1B
Gene Names
RAB1B
Chain
chain:1-201
Reference Genes
BioGPS Gene:81876 RAB1B
COSMIC (genes):RAB1B RAB1B
CTD Gene:81876 RAB1B
dbSNP Gene:81876 RAB1B
ENSEMBL:ENSG00000174903 RAB1B
HGNC:18370 RAB1B
KEGG:hsa:81876 RAB1B
Monarch:81876 RAB1B
NCBI Entrez Gene:81876 RAB1B
OMIM:612565 RAB1B
UCSC:Q9H0U4 RAB1B
Reference Transcript
RefSeq:NM_030981.3 RAB1B
Other Identifiers
11716668_at
11716669_x_at
11716670_s_at
16727351
220964_PM_s_at
220964_s_at
3205561
3205562
3205563
3205564
3205565
3205566
3205568
3336075
3336080
3336081
3336082
3336085
3336086
3336087
3336088
3336089
3336090
3336091
3336092
3336093
3336095
3336096
43390_s_at
65902_at
65903_at
7941583
81876
A_23_P64090
A_33_P3329607
GE61198
GO:0000045
GO:0000139
GO:0000166
GO:0003924
GO:0003925
GO:0005515
GO:0005525
GO:0005737
GO:0005789
GO:0005793
GO:0005794
GO:0005829
GO:0006886
GO:0006888
GO:0006914
GO:0007030
GO:0012505
GO:0015031
GO:0016020
GO:0016192
GO:0016787
GO:0019068
GO:0030133
GO:0031410
GO:0033116
GO:0034045
GO:0043226
GO:0048471
GO:0070062
GO:0098772
GO:1903020
GO:2000785
HMNXSV003029388
ILMN_1664030
ILMN_1762802
PH_hs_0015483
PH_hs_0038055
TC11000657.hg
g13569961_3p_s_at
Participates
as a component of
GGC-RAB1B:GTP [transport vesicle membrane] (Homo sapiens)
Other forms of this molecule
p-T191-RAB1B [Golgi membrane]
RAB1B [Golgi membrane]
RAB1B [cytosol]
RAB1B [endoplasmic reticulum-Golgi intermediate compartment membrane]
RAB1B [transport vesicle]
GGC-RAB1B [cytosol]
RAB1B [endoplasmic reticulum membrane]
Inferred To
RabX6 [transport vesicle membrane]
(Drosophila melanogaster)
Homologues of GGC-RAB1B [transport vesicle membrane]
(Danio rerio)
Homologues of GGC-RAB1B [transport vesicle membrane]
(Dictyostelium discoideum)
Homologues of GGC-RAB1B [transport vesicle membrane]
(Drosophila melanogaster)
Homologues of GGC-RAB1B [transport vesicle membrane]
(Saccharomyces cerevisiae)
rab1bb [transport vesicle membrane]
(Danio rerio)
rabW [transport vesicle membrane]
(Dictyostelium discoideum)
rab-1 [transport vesicle membrane]
(Caenorhabditis elegans)
Rab1 [transport vesicle membrane]
(Drosophila melanogaster)
rab1E [transport vesicle membrane]
(Dictyostelium discoideum)
rab1ba [transport vesicle membrane]
(Danio rerio)
rsmM [transport vesicle membrane]
(Dictyostelium discoideum)
GGC-RAB1B [transport vesicle membrane]
(Canis familiaris)
GGC-RAB1B [transport vesicle membrane]
(Danio rerio)
GGC-RAB1B [transport vesicle membrane]
(Dictyostelium discoideum)
GGC-RAB1B [transport vesicle membrane]
(Mus musculus)
GGC-RAB1B [transport vesicle membrane]
(Plasmodium falciparum)
GGC-RAB1B [transport vesicle membrane]
(Rattus norvegicus)
GGC-RAB1B [transport vesicle membrane]
(Saccharomyces cerevisiae)
GGC-RAB1B [transport vesicle membrane]
(Schizosaccharomyces pombe)
rab1ab [transport vesicle membrane]
(Danio rerio)
RAB1B [transport vesicle membrane]
(Bos taurus)
Modified Residues
Name
S-geranylgeranyl-L-cysteine at 200
Coordinate
200
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Name
S-geranylgeranyl-L-cysteine at 201
Coordinate
201
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Cross References
RefSeq
NP_112243.1
OpenTargets
ENSG00000174903
ENSEMBL
ENST00000311481
,
ENSG00000174903
,
ENSP00000310226
HPA
ENSG00000174903-RAB1B
GeneCards
RAB1B
PRO
Q9H0U4
Pharos - Targets
Q9H0U4
GlyGen
Q9H0U4
PDB
3NKV
,
4HLQ
,
4I1O
,
5SZK
,
5SZH
,
3JZA
,
8ALK
,
6SKU
,
5O74
HMDB Protein
HMDBP08509
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.59
5
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.547
2
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
0.527
5
UniProt:Q92696 RABGGTA
2
RABGGTA [plasma membrane]
(R-HSA-6801086)
RABGGTA [cytosol]
(R-HSA-8870418)
0.527
3
UniProt:P24386 CHM
1
CHM [cytosol]
(R-HSA-6801097)
0.527
3
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