Reactome | GGC-RAB31 [cytosol]

GGC-RAB31 [cytosol]

Stable Identifier

R-HSA-8873974

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ras-related protein Rab-31, RAB31_HUMAN

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - Rab regulation of trafficking (Homo sapiens)
    - RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
      - RAB31 GEFs exchange GTP for GDP on RAB31 (Homo sapiens)
        
        GGC-RAB31:GDP:GDIs,CHMs [cytosol] (Homo sapiens)
        
        GGC-RAB31:GDP [cytosol] (Homo sapiens)
        
        GGC-RAB31 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q13636 RAB31

Gene Names

RAB31, RAB22B

Chain

chain:1-194

Reference Genes

BioGPS Gene:11031 RAB31

COSMIC (genes):RAB31 RAB31

CTD Gene:11031 RAB31

dbSNP Gene:11031 RAB31

ENSEMBL:ENSG00000168461 RAB31

ENSEMBL:ENSG00000168461.13 RAB31

HGNC:9771 RAB31

KEGG Gene (Homo sapiens):11031 RAB31

Monarch:11031 RAB31

NCBI Gene:11031 RAB31

OMIM:605694 RAB31

UCSC:Q13636 RAB31

Reference Transcript

RefSeq:NM_006868.3 RAB31

Other Identifiers

11031

11716018_s_at

11716019_at

11757731_s_at

11757833_a_at

16850923

217762_PM_s_at

217762_s_at

217763_PM_s_at

217763_s_at

217764_PM_s_at

217764_s_at

33371_s_at

33372_at

3778505

3778506

3778507

3778538

3778546

3778552

3778553

3778569

3778575

3778576

3778577

57154_at

65819_at

8020110

A_23_P141688

A_24_P236799

GE81690

GE88629

GO:0000166

GO:0001891

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005768

GO:0005769

GO:0005794

GO:0005829

GO:0005886

GO:0006886

GO:0012505

GO:0016020

GO:0016192

GO:0016787

GO:0019003

GO:0030667

GO:0030670

GO:0031410

GO:0031623

GO:0031901

GO:0032588

GO:0032869

GO:0036186

GO:0043001

GO:0043226

GO:0045055

GO:0045335

GO:0060100

GO:0061024

GO:0072659

GO:0090382

HMNXSV003007528

Hs.223025.0.S2_3p_a_at

ILMN_1660691

PH_hs_0012499

TC18000047.hg

U59877_s_at

g5803130_3p_a_at

g9963780_3p_a_at

Participates

as a component of

GGC-RAB31:GDP [cytosol] (Homo sapiens)

as a candidate of

GGC-RABs [cytosol] (Homo sapiens)

Other forms of this molecule

GGC-RAB31 [early endosome membrane]

RAB31 [cytosol]

RAB31 [plasma membrane]

RAB31 [secretory granule membrane]

Inferred To

Homologues of GGC-RAB31 [cytosol] (Dictyostelium discoideum)

GGC-RAB22A [cytosol] (Dictyostelium discoideum)

GGC-RAB31 [cytosol] (Canis familiaris)

GGC-RAB31 [cytosol] (Dictyostelium discoideum)

GGC-RAB31 [cytosol] (Mus musculus)

GGC-RAB31 [cytosol] (Rattus norvegicus)

rab31 [cytosol] (Xenopus tropicalis)

RAB31 [cytosol] (Bos taurus)

RAB31 [cytosol] (Gallus gallus)

RAB31 [cytosol] (Sus scrofa)

Modified Residues

Name

S-geranylgeranyl-L-cysteine at 193

Coordinate

193

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Name

S-geranylgeranyl-L-cysteine at 194

Coordinate

194

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Cross References

RefSeq

NP_006859.2

OpenTargets

ENSG00000168461

GeneCards

Q13636

HPA

ENSG00000168461-RAB31

Ensembl

ENSP00000461945, ENSG00000168461, ENST00000578921

PRO

Q13636

Pharos - Targets

Q13636

PDB

2FG5

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P27797 CALR	6	CALR [integral component of lumenal side of endoplasmic reticulum membrane] (R-HSA-985502) CALR [endoplasmic reticulum lumen] (R-HSA-195905) CALR [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863866) CALR [phagocytic vesicle membrane] (R-HSA-1236879) CALR [extracellular region] (R-HSA-2197641) CALR [endocytic vesicle lumen] (R-HSA-2239448)	0.556	3