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PLAUR(23-335) [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-162866
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
urokinase plasminogen activator receptor precursor, uPAR precursor
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Post-translational modification: synthesis of GPI-anchored proteins (Homo sapiens)
Attachment of GPI anchor to uPAR (Homo sapiens)
uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide (Homo sapiens)
PLAUR(23-335) [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q03405 PLAUR
Gene Names
PLAUR, MO3, UPAR
Chain
signal peptide:1-22, chain:23-305, propeptide:306-335
Reference Genes
BioGPS Gene:5329 PLAUR
COSMIC (genes):PLAUR PLAUR
CTD Gene:5329 PLAUR
dbSNP Gene:5329 PLAUR
ENSEMBL:ENSG00000011422 PLAUR
HGNC:9053 PLAUR
KEGG Gene (Homo sapiens):5329 PLAUR
Monarch:5329 PLAUR
NCBI Gene:5329 PLAUR
OMIM:173391 PLAUR
UCSC:Q03405 PLAUR
Reference Transcript
RefSeq:NM_002659.3 PLAUR
RefSeq:NM_001005376.2 PLAUR
RefSeq:NM_001301037.1 PLAUR
RefSeq:NM_001005377.2 PLAUR
Other Identifiers
11738053_x_at
11742818_a_at
11742819_at
11743062_a_at
11743063_x_at
16873060
189_s_at
210845_s_at
211924_s_at
214866_at
3864552
3864553
3864554
3864558
3864559
3864560
3864563
3864564
3864565
3864566
3864576
3864577
3864578
3864584
3864585
41169_at
5329
8037374
A_23_P16469
GE80529
GO:0001934
GO:0002376
GO:0003674
GO:0005102
GO:0005515
GO:0005575
GO:0005576
GO:0005622
GO:0005737
GO:0005783
GO:0005788
GO:0005789
GO:0005886
GO:0005887
GO:0005925
GO:0006464
GO:0006810
GO:0006935
GO:0006950
GO:0007005
GO:0007155
GO:0007165
GO:0007596
GO:0008150
GO:0008219
GO:0009986
GO:0016020
GO:0016021
GO:0016192
GO:0019898
GO:0019899
GO:0019904
GO:0030054
GO:0030162
GO:0030377
GO:0031225
GO:0031410
GO:0034112
GO:0035579
GO:0038023
GO:0038195
GO:0040011
GO:0042730
GO:0042995
GO:0043066
GO:0043226
GO:0043312
GO:0043388
GO:0045742
GO:0090200
GO:2001243
GO:2001268
HMNXSV003001685
HMNXSV003015628
Hs.179657.2.S1_3p_at
ILMN_1666507
ILMN_1691508
ILMN_2374340
ILMN_2408543
PH_hs_0032020
TC19001593.hg
U09937_rna1_s_at
X74039_at
g13641308_3p_s_at
g517197_3p_a_at
Participates
as an input of
uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide (Homo sapiens)
Other forms of this molecule
PLAUR [endoplasmic reticulum membrane]
GPI-PLAUR [endoplasmic reticulum membrane]
PLAUR(306-335) [endoplasmic reticulum lumen]
GPI-PLAUR [plasma membrane]
PLAUR [specific granule membrane]
PLAUR [plasma membrane]
Inferred To
Homologues of PLAUR(23-335) [endoplasmic reticulum membrane]
(Xenopus tropicalis)
Plaur [endoplasmic reticulum membrane]
(Mus musculus)
Plaur [endoplasmic reticulum membrane]
(Rattus norvegicus)
PLAUR [endoplasmic reticulum membrane]
(Canis familiaris)
PLAUR [endoplasmic reticulum membrane]
(Sus scrofa)
LOC101731406 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
LOC101730998 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_002650.1
,
NP_001005377.1
,
NP_001287966.1
,
NP_001005376.1
OpenTargets
ENSG00000011422
GeneCards
Q03405
HPA
ENSG00000011422-PLAUR
ZINC - Substances
UPAR_HUMAN
Ensembl
ENSP00000339328
,
ENST00000340093
,
ENST00000221264
,
ENSP00000221264
,
ENST00000339082
,
ENSG00000011422
,
ENSP00000342049
ZINC target
Q03405
PRO
Q03405
Pharos - Targets
Q03405
ZINC - Predictions - Purchasable
UPAR_HUMAN
GlyGen
Q03405
PDB
3U74
,
3U73
,
1YWH
,
4K24
,
2FD6
,
3BT2
,
3BT1
,
4QTI
,
2I9B
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P03950 ANG
2
ANG [cytosol]
(R-HSA-9708345)
ANG [extracellular region]
(R-HSA-5692435)
0.571
5
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