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DHRS4 [peroxisomal matrix]
Stable Identifier
R-HSA-9033097
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
peroxisomal matrix
Synonyms
Dehydrogenase/reductase SDR family member 4 ecNumber1.1.1.184/ecNumber, DHRS4_HUMAN
Locations in the PathwayBrowser
Expand all
Protein localization (Homo sapiens)
Peroxisomal protein import (Homo sapiens)
Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Homo sapiens)
Cargo proteins containing PTS1 [peroxisomal matrix] (Homo sapiens)
DHRS4 [peroxisomal matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BTZ2 DHRS4
Gene Names
DHRS4, SDR25C2, UNQ851/PRO1800
Chain
chain:1-278
Reference Genes
BioGPS Gene:10901 DHRS4
COSMIC (genes):DHRS4 DHRS4
CTD Gene:10901 DHRS4
dbSNP Gene:10901 DHRS4
ENSEMBL:ENSG00000157326 DHRS4
ENSEMBL_homo_sapiens_GENE:ENSG00000157326.19 DHRS4
ENSEMBL_homo_sapiens_GENE:ENSG00000284807.3 DHRS4
HGNC:16985 DHRS4
KEGG Gene (Homo sapiens):10901 DHRS4
Monarch:10901 DHRS4
NCBI Gene:10901 DHRS4
OMIM:611596 DHRS4
UCSC:Q9BTZ2 DHRS4
Reference Transcript
RefSeq:NM_001282990.1 DHRS4
RefSeq:NM_001282991.1 DHRS4
RefSeq:NM_021004.3 DHRS4
RefSeq:NM_001282987.1 DHRS4
RefSeq:NM_001282988.1 DHRS4
RefSeq:NM_001282989.1 DHRS4
Other Identifiers
10901
11744805_x_at
11753211_x_at
11756004_s_at
11756015_s_at
11762823_x_at
16782418
218021_PM_at
218021_at
3529310
3529311
3529312
3529313
3529317
3529322
3529323
3529325
3529327
3529330
3529335
3529336
3529337
3529338
3529339
3529351
3529353
3529354
3529355
3529356
3529358
3529360
3529361
3529362
3529363
3529364
3529379
3529380
3529382
3529383
46220_at
7973448
7973458
A_23_P162982
A_33_P3213997
A_33_P3383422
A_33_P3383431
A_33_P3383436
GE55941
GO:0000253
GO:0001758
GO:0003824
GO:0004090
GO:0005634
GO:0005739
GO:0005777
GO:0005778
GO:0005782
GO:0005783
GO:0005789
GO:0005829
GO:0006066
GO:0006629
GO:0008202
GO:0016491
GO:0016655
GO:0018455
GO:0033703
GO:0042180
GO:0042572
GO:0042574
GO:0042802
GO:0043226
GO:0052650
GO:2000379
HMNXSV003030378
HMNXSV003032180
HMNXSV003038237
ILMN_1762666
ILMN_2185884
PH_hs_0036497
PH_hs_0038131
TC14001604.hg
g10337604_3p_at
Participates
as a member of
Cargo proteins containing PTS1 [peroxisomal matrix] (Homo sapiens)
Other forms of this molecule
DHRS4 [endoplasmic reticulum membrane]
DHRS4 [cytosol]
Inferred To
DHRS4 [peroxisomal matrix]
(Bos taurus)
DHRS4 [peroxisomal matrix]
(Caenorhabditis elegans)
DHRS4 [peroxisomal matrix]
(Canis familiaris)
DHRS4 [peroxisomal matrix]
(Gallus gallus)
DHRS4 [peroxisomal matrix]
(Mus musculus)
DHRS4 [peroxisomal matrix]
(Rattus norvegicus)
DHRS4 [peroxisomal matrix]
(Sus scrofa)
Dhrs4 [peroxisomal matrix]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001269919.1
,
NP_066284.2
,
NP_001269918.1
,
NP_001269917.1
,
NP_001269920.1
,
NP_001269916.1
OpenTargets
ENSG00000157326
GeneCards
Q9BTZ2
HPA
ENSG00000157326-DHRS4
Ensembl
ENSP00000496426
,
ENST00000397075
,
ENSP00000380265
,
ENST00000397074
,
ENST00000646997
,
ENST00000559632
,
ENST00000645602
,
ENSG00000284807
,
ENSP00000452645
,
ENSG00000157326
,
ENST00000647030
,
ENST00000647154
,
ENSP00000380264
,
ENSP00000453367
,
ENST00000313250
,
ENSP00000453983
,
ENST00000558263
,
ENST00000558581
,
ENSP00000495868
,
ENSP00000495877
,
ENSP00000326219
,
ENSP00000496349
PRO
Q9BTZ2
Pharos - Targets
Q9BTZ2
HMDB Protein
HMDBP00076
PDB
3O4R
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06865 HEXA
3
HEXA Y427Ifs*5 [lysosomal lumen]
(R-HSA-3700918)
HEXA(88-528) [lysosomal lumen]
(R-HSA-1605799)
HEXA(23-73) [lysosomal lumen]
(R-HSA-9842401)
0.527
2
UniProt:Q03405 PLAUR
7
PLAUR [endoplasmic reticulum membrane]
(R-HSA-162703)
GPI-PLAUR [endoplasmic reticulum membrane]
(R-HSA-162687)
PLAUR(306-335) [endoplasmic reticulum lumen]
(R-HSA-162707)
PLAUR(23-335) [endoplasmic reticulum membrane]
(R-HSA-162866)
GPI-PLAUR [plasma membrane]
(R-HSA-158946)
PLAUR [plasma membrane]
(R-HSA-6806165)
GPI-PLAUR [specific granule membrane]
(R-HSA-6806143)
0.527
2
UniProt:Q96CA5 BIRC7
1
BIRC7 [cytosol]
(R-HSA-50855)
0.527
2
UniProt:Q9UH99 SUN2
1
SUN2 [nuclear envelope]
(R-HSA-912382)
0.527
4
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