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MAN2A1 [Golgi membrane]
Stable Identifier
R-HSA-975823
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Alpha-mannosidase 2, MA2A1_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
Late SARS-CoV-2 Infection Events (Homo sapiens)
Translation of Structural Proteins (Homo sapiens)
Maturation of spike protein (Homo sapiens)
Spike trimer glycoside chains are extended (Homo sapiens)
MAN2A1 [Golgi membrane] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
N-glycan antennae elongation in the medial/trans-Golgi (Homo sapiens)
Reactions specific to the complex N-glycan synthesis pathway (Homo sapiens)
Trimming of mannoses on the alpha1,6 arm by MAN2A1 (Homo sapiens)
MAN2:Zn2+ [Golgi membrane] (Homo sapiens)
MAN2A1:Zn2+ [Golgi membrane] (Homo sapiens)
MAN2A1 [Golgi membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Intra-Golgi traffic (Homo sapiens)
Formation of cis-SNARE complex and membrane fusion in intra-Golgi retrograde traffic (Homo sapiens)
COG complex:CUX1 dimer:GOLGA5 dimer:STX5:PalmC-YKT6:BET1L:GOSR1:intra-Golgi retrograde cargo [Golgi membrane] (Homo sapiens)
intra-Golgi cargo [Golgi membrane] (Homo sapiens)
MAN2A1 [Golgi membrane] (Homo sapiens)
intra-Golgi cargo [Golgi membrane] (Homo sapiens)
MAN2A1 [Golgi membrane] (Homo sapiens)
The COG complex and CUX1 and GOLGA5 dimers contribute to intra-Golgi vesicle tethering (Homo sapiens)
COG complex:CUX1 dimer:GOLGA5 dimer:STX5:PalmC-YKT6:BET1L:GOSR1:intra-Golgi retrograde cargo [Golgi membrane] (Homo sapiens)
intra-Golgi cargo [Golgi membrane] (Homo sapiens)
MAN2A1 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q16706 MAN2A1
Gene Names
MAN2A1, MANA2
Chain
chain:1-1144
Reference Genes
BioGPS Gene:4124 MAN2A1
COSMIC (genes):MAN2A1 MAN2A1
CTD Gene:4124 MAN2A1
dbSNP Gene:4124 MAN2A1
ENSEMBL:ENSG00000112893 MAN2A1
ENSEMBL_homo_sapiens_GENE:ENSG00000112893.10 MAN2A1
HGNC:6824 MAN2A1
KEGG Gene (Homo sapiens):4124 MAN2A1
Monarch:4124 MAN2A1
NCBI Gene:4124 MAN2A1
OMIM:154582 MAN2A1
UCSC:Q16706 MAN2A1
Reference Transcript
RefSeq:NM_002372.3 MAN2A1
Other Identifiers
11725471_a_at
16987844
205105_PM_at
205105_at
226538_PM_at
226538_at
235103_PM_at
235103_at
2823553
2823554
2823555
2823556
2823557
2823558
2823569
2823570
2823572
2823578
2823583
2823584
2823587
2823588
2823589
2823590
2823591
2823593
2823603
2823604
2823605
2823606
2823612
2823613
2823614
2823615
2823616
2823620
2823621
2823627
2823630
2823631
2823632
39663_at
4124
77854_at
8107234
A_14_P116643
A_23_P18931
A_23_P360769
D63998_at
GE57285
GO:0000139
GO:0001701
GO:0001889
GO:0003824
GO:0004559
GO:0004572
GO:0005576
GO:0005615
GO:0005794
GO:0005797
GO:0005801
GO:0005975
GO:0006013
GO:0006486
GO:0006491
GO:0006517
GO:0007005
GO:0007033
GO:0007585
GO:0008152
GO:0015923
GO:0016020
GO:0016787
GO:0016798
GO:0016799
GO:0019082
GO:0030154
GO:0030246
GO:0036211
GO:0042802
GO:0042803
GO:0043226
GO:0046872
GO:0048286
GO:0048856
GO:0050769
GO:0060042
GO:0070062
GO:1901135
HMNXSV003041323
HMNXSV003055213
Hs.204295.0.S1_3p_at
Hs.204295.0.S1_3p_x_at
Hs.63368.0.A1_3p_at
ILMN_2147435
ILMN_2147440
PH_hs_0020904
TC05000515.hg
g4758697_3p_at
Participates
as a candidate of
intra-Golgi cargo [Golgi membrane] (Homo sapiens)
as a component of
MAN2A1:Zn2+ [Golgi membrane] (Homo sapiens)
Other forms of this molecule
MAN2A1 [transport vesicle]
Inferred To
aman-3 [Golgi membrane]
(Caenorhabditis elegans)
alpha-Man-IIb [Golgi membrane]
(Drosophila melanogaster)
aman-2 [Golgi membrane]
(Caenorhabditis elegans)
MAN2A1 [Golgi membrane]
(Bos taurus)
MAN2A1 [Golgi membrane]
(Canis familiaris)
MAN2A1 [Golgi membrane]
(Drosophila melanogaster)
MAN2A1 [Golgi membrane]
(Gallus gallus)
MAN2A1 [Golgi membrane]
(Mus musculus)
MAN2A1 [Golgi membrane]
(Rattus norvegicus)
MAN2A1 [Golgi membrane]
(Sus scrofa)
man2a1 [Golgi membrane]
(Xenopus tropicalis)
Homologues of MAN2A1 [Golgi membrane]
(Caenorhabditis elegans)
Homologues of MAN2A1 [Golgi membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_002363.2
OpenTargets
ENSG00000112893
ZINC - Substances
MA2A1_HUMAN
HPA
ENSG00000112893-MAN2A1
GeneCards
Q16706
Ensembl
ENSG00000112893
,
ENST00000261483
,
ENSP00000261483
ZINC target
Q16706
PRO
Q16706
Pharos - Targets
Q16706
ZINC - Predictions - Purchasable
MA2A1_HUMAN
HMDB Protein
HMDBP00867
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