Reactome | p-S133-CREB1 [nucleoplasm]

p-S133-CREB1 [nucleoplasm]

Stable Identifier

R-HSA-111910

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

phospho-CREB, p-S133-CREB-A

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External Reference Information

External Reference

UniProt:P16220-1 CREB1

Gene Names

CREB1

Other Identifiers

11732302_a_at

11732303_a_at

11732304_a_at

11732305_a_at

11732306_x_at

11732307_a_at

11736195_a_at

1385

16890067

204312_PM_x_at

204312_x_at

204313_PM_s_at

204313_s_at

204314_PM_s_at

204314_s_at

214513_PM_s_at

214513_s_at

225565_PM_at

225565_at

225572_PM_at

225572_at

2359035

237289_PM_at

237289_at

2525055

2525056

2525062

2525063

2525064

2525065

2525068

2525069

2525070

2525071

2525072

2525073

2525074

2525076

2525077

2525078

2525079

2525080

2525081

2525082

2525089

2525090

2525091

2525092

2525093

2525094

2525095

2525096

2525097

2525099

2525100

2525101

2525102

2525104

2525106

2545979

2658697

2738879

3035128

3053863

3080259

3293144

3302039

37535_at

3939416

65541_at

68972_at

80261_s_at

8047839

85167_r_at

877_at

90568_at

A_14_P121644

A_14_P124680

A_14_P139324

A_23_P79231

A_24_P105721

GE558666

GE57016

GE57897

GE891644

GO:0000785

GO:0000791

GO:0000977

GO:0000978

GO:0000981

GO:0001228

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005667

GO:0006351

GO:0006355

GO:0006357

GO:0006468

GO:0007165

GO:0007409

GO:0007595

GO:0007613

GO:0007623

GO:0008361

GO:0009410

GO:0010944

GO:0014074

GO:0016071

GO:0019899

GO:0019933

GO:0021983

GO:0030154

GO:0030316

GO:0030879

GO:0033363

GO:0033762

GO:0035497

GO:0035729

GO:0040018

GO:0042789

GO:0042802

GO:0043066

GO:0043226

GO:0043565

GO:0045600

GO:0045672

GO:0045893

GO:0045944

GO:0046879

GO:0046887

GO:0046889

GO:0048511

GO:0048856

GO:0050821

GO:0050877

GO:0055025

GO:0060428

GO:0060430

GO:0060509

GO:0061629

GO:0071294

GO:0071300

GO:0071363

GO:0090575

GO:0140110

GO:1904322

GO:1990589

GO:1990830

GO:1990837

GO:2000224

HMNXSV003006671

HMNXSV003048597

Hs.193814.0.A1_3p_at

Hs.22315.0.A1_3p_at

Hs.22315.0.A2_3p_at

Hs.79194.0.A1_3p_a_at

Hs.79194.0.A2_3p_a_at

ILMN_1841334

ILMN_2334242

ILMN_2334243

ILMN_2382758

M27691_at

PH_hs_0022033

PH_hs_0036660

S78693_f_at

TC02001229.hg

TC02003791.hg

X60003_s_at

g4758053_3p_a_at

Participates

as an output of

as an input of

as a component of

Other forms of this molecule

CREB1 [nucleoplasm]

Inferred To

phospho-creb1a [nucleoplasm] (Danio rerio)

phospho-CrebB [nucleoplasm] (Drosophila melanogaster)

p-S133-Creb1 [nucleoplasm] (Mus musculus)

p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)

phospho-CREB1 [nucleoplasm] (Bos taurus)

phospho-CREB1 [nucleoplasm] (Canis familiaris)

phospho-CREB1 [nucleoplasm] (Gallus gallus)

phospho-creb1 [nucleoplasm] (Xenopus tropicalis)

phospho-p-S133-CREB1 [nucleoplasm] (Caenorhabditis elegans)

phospho-p-S133-CREB1 [nucleoplasm] (Sus scrofa)

Modified Residues

Name

O-phospho-L-serine at 133

Coordinate

133

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_004370.1, NP_604391.1, XP_011508949.1, XP_011508947.1

ENSEMBL

ENSP00000387699, ENST00000432329, ENSG00000118260, ENST00000430624, ENSP00000405539, ENSP00000236995, ENST00000353267

OpenTargets

ENSG00000118260

ZINC - Substances

CREB1_HUMAN

ZINC - Biogenic

CREB1_HUMAN

ZINC target

P16220

PRO

P16220

GlyGen

P16220

PDB

7TBH, 5ZKO, 5ZK1, 2LXT

GeneCards

CREB1

HPA

ENSG00000118260-CREB1

Pharos - Targets

P16220

Orphanet

CREB1

HMDB Protein

HMDBP02133

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P18846 ATF1	2	p-S63-ATF1 [nucleoplasm] (R-HSA-199897) ATF1 [nucleoplasm] (R-HSA-199900)	0.697	6
UniProt:O00470 MEIS1	1	MEIS1 [nucleoplasm] (R-HSA-5490327)	0.677	9
UniProt:Q92793 CREBBP	4	CREBBP [nucleoplasm] (R-HSA-193545) CREBBP [cytosol] (R-HSA-9756493) FOXO4-S-S-CREBBP [nucleoplasm] (R-HSA-9617684) monoSUMO1-K998,K1033,K1056-CREBBP [nucleoplasm] (R-HSA-3927877)	0.589	2
UniProt:O95644 NFATC1	3	p-12S-NFATC1 [cytosol] (R-HSA-2025953) p-S257-NFATC1 [cytosol] (R-HSA-2685618) p-S257-NFATC1 [nucleoplasm] (R-HSA-2025935)	0.576	3
UniProt:O75928-2 PIAS2	1	PIAS2-2 [nucleoplasm] (R-HSA-2993779)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q13469 NFATC2	4	p-14S-NFATC2 [cytosol] (R-HSA-2025848) p-S243-NFATC2 [cytosol] (R-HSA-2685626) p-S243-NFATC2 [nucleoplasm] (R-HSA-2025894) NFATC2 [nucleoplasm] (R-HSA-3791114)	0.499	2
UniProt:O00141 SGK1	4	p-T256,S422-SGK1 [nucleoplasm] (R-HSA-9612512) p-T256,S422-SGK1 [cytosol] (R-HSA-6795449) p-S422-SGK1 [cytosol] (R-HSA-6795313) SGK1 [cytosol] (R-HSA-2682356)	0.488	2
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.462	3

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