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p-S133-CREB1 homodimer [nucleoplasm]
Stable Identifier
R-HSA-111911
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
phospho-CREB dimer
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Transcriptional regulation of granulopoiesis (Homo sapiens)
CEBPB gene transcription is enhanced by phospho-CREB1 and phospho-STAT3 (Homo sapiens)
CEBPB gene:p-S133-CREB1 dimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
Phospho-CREB1 binds the promoter of the CEBPB gene (Homo sapiens)
CEBPB gene:p-S133-CREB1 dimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by MECP2 (Homo sapiens)
MECP2 regulates neuronal receptors and channels (Homo sapiens)
MECP2:CREB1 complex binds SLC2A3 gene (Homo sapiens)
MECP2:p-S133-CREB1 [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
MECP2:p-S133-CREB1:SLC2A3 gene [nucleoplasm] (Homo sapiens)
MECP2:p-S133-CREB1 [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
SLC2A3 gene expression is stimulated by MECP2:CREB1 complex (Homo sapiens)
MECP2:p-S133-CREB1 [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
MECP2:p-S133-CREB1:SLC2A3 gene [nucleoplasm] (Homo sapiens)
MECP2:p-S133-CREB1 [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
MECP2 regulates transcription of neuronal ligands (Homo sapiens)
MECP2:CREB1 binds SST gene promoter (Homo sapiens)
MECP2:p-S133-CREB1 [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
MECP2:p-S133-CREB1:SST gene [nucleoplasm] (Homo sapiens)
MECP2:p-S133-CREB1 [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
SST gene expression is stimulated by MECP2 and CREB1 (Homo sapiens)
MECP2:p-S133-CREB1 [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
MECP2:p-S133-CREB1:SST gene [nucleoplasm] (Homo sapiens)
MECP2:p-S133-CREB1 [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
Regulation of MECP2 expression and activity (Homo sapiens)
MECP2 binds CREB1 (Homo sapiens)
MECP2:p-S133-CREB1 [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
MIR132 gene expression is stimulated by p-S133-CREB1 (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1:MIR132 gene [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 binds MIR132 gene promoter (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1:MIR132 gene [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
DAG and IP3 signaling (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
CaMK IV-mediated phosphorylation of CREB (Homo sapiens)
Dimerization of p-S133-CREB1 (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
PKA-mediated phosphorylation of CREB (Homo sapiens)
Dimerization of p-S133-CREB1 (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Opioid Signalling (Homo sapiens)
G-protein mediated events (Homo sapiens)
PLC beta mediated events (Homo sapiens)
Ca-dependent events (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
CaMK IV-mediated phosphorylation of CREB (Homo sapiens)
Dimerization of p-S133-CREB1 (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
PKA-mediated phosphorylation of CREB (Homo sapiens)
Dimerization of p-S133-CREB1 (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Signaling by NOTCH2 (Homo sapiens)
NOTCH2 intracellular domain regulates transcription (Homo sapiens)
NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter (Homo sapiens)
NOTCH2 coactivator complex:p-S133-CREB1:EP300:GZMB Gene [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
NOTCH2 stimulates GZMB transcription (Homo sapiens)
NOTCH2 coactivator complex:p-S133-CREB1:EP300:GZMB Gene [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Extra-nuclear estrogen signaling (Homo sapiens)
Estrogen-dependent nuclear events downstream of ESR-membrane signaling (Homo sapiens)
BCL gene expression downstream of ESR1 (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
Dimerization of p-S133-CREB1 (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
ESR1-dependent CCND1 expression (Homo sapiens)
CCND1 gene:p-S133 CREB1 dimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133 CREB1 dimer binds the CCND1 promoter (Homo sapiens)
CCND1 gene:p-S133 CREB1 dimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Nuclear Events (kinase and transcription factor activation) (Homo sapiens)
NGF-stimulated transcription (Homo sapiens)
ARC gene expression (Homo sapiens)
p-S133-CREB1:MEF2D:SRF:ARC gene [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
Dimerization of p-S133-CREB1 (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
EGR1 gene expression (Homo sapiens)
EGR1 gene:p-S133 CREB:p-S103 SRF [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
ID1 and ID3 gene expression (Homo sapiens)
ID1,ID3 genes:p-S133-CREB1:LYL1:EP300 [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133 CREB and p-S103 SRF bind the EGR1 promoter (Homo sapiens)
EGR1 gene:p-S133 CREB:p-S103 SRF [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes (Homo sapiens)
ID1,ID3 genes:p-S133-CREB1:LYL1:EP300 [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133 CREB1, MEF2D and SRF bind the ARC gene (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
p-S133-CREB1:MEF2D:SRF:ARC gene [nucleoplasm] (Homo sapiens)
p-S133-CREB1 homodimer [nucleoplasm] (Homo sapiens)
Participants
components
2 x
p-S133-CREB1 [nucleoplasm] (Homo sapiens)
Participant Of
input
MECP2 binds CREB1
NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter
p-S133 CREB and p-S103 SRF bind the EGR1 promoter
p-S133 CREB1 dimer binds the CCND1 promoter
p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
p-S133 CREB1, MEF2D and SRF bind the ARC gene
p-S133-CREB1 binds MIR132 gene promoter
Phospho-CREB1 binds the promoter of the CEBPB gene
hasComponent
CCND1 gene:p-S133 CREB1 dimer [nucleoplasm]
CEBPB gene:p-S133-CREB1 dimer [nucleoplasm]
EGR1 gene:p-S133 CREB:p-S103 SRF [nucleoplasm]
ID1,ID3 genes:p-S133-CREB1:LYL1:EP300 [nucleoplasm]
MECP2:p-S133-CREB1 [nucleoplasm]
NOTCH2 coactivator complex:p-S133-CREB1:EP300:GZMB Gene [nucleoplasm]
p-S133-CREB1:MEF2D:SRF:ARC gene [nucleoplasm]
p-S133-CREB1:MIR132 gene [nucleoplasm]
output
Dimerization of p-S133-CREB1
This entity regulates
Positively
BCL gene expression downstream of ESR1
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