Bruce May

 ORCID
https://orcid.org/0000-0001-5193-0855
Project
Reactome
Affiliation
Cold Spring Harbor Laboratory
Authored Pathways (15/248)
Date Identifier Pathway Reference
2025-12-08 R-HSA-9976102 Differentiation of naive CD4+ T cells to T helper 2 cells (Th2 cells) BibTex
2025-06-06 R-HSA-9954709 Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide BibTex
2025-06-06 R-HSA-9954716 ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA BibTex
2025-06-06 R-HSA-9954714 PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA BibTex
2025-05-19 R-HSA-9948299 Ribosome-associated quality control BibTex
2025-04-12 R-HSA-9945266 Differentiation of T cells BibTex
2025-03-17 R-HSA-9942503 Differentiation of naive CD4+ T cells to T helper 1 cells (Th1 cells) BibTex
2025-01-29 R-HSA-9937383 Mitochondrial ribosome-associated quality control BibTex
2025-01-25 R-HSA-9937008 Mitochondrial mRNA modification BibTex
2024-12-28 R-HSA-9933387 RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression BibTex
2024-12-17 R-HSA-9932298 Degradation of CRY and PER proteins BibTex
2024-12-09 R-HSA-9931510 Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes BibTex
2024-12-09 R-HSA-9931509 Expression of BMAL (ARNTL), CLOCK, and NPAS2 BibTex
2024-12-09 R-HSA-9931521 The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex BibTex
2024-12-09 R-HSA-9931530 Phosphorylation and nuclear translocation of the CRY:PER:kinase complex BibTex
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Authored Reactions (15/2,685)
Date Identifier Reaction Reference
2025-12-29 R-HSA-9978250 Phosphorylated STAT5 dimer binds the IL4R gene BibTex
2025-12-29 R-HSA-9978246 Phosphorylated STAT5 dimer positively regulates expression of IL4R BibTex
2025-12-29 R-MMU-9978257 Phosphorylated Stat5 dimers positively regulate expression of Il4ra BibTex
2025-12-27 R-MMU-9978110 Gata3, Chd4, Ep300, p-S243-Nfatc2 (p-S243-Nfat1), Fos:Jun (AP-1), Klf13, and Maf bind the Il4 gene BibTex
2025-12-27 R-MMU-9978102 Gata3, Chd4, Ep300, Nfatc2 (Nfat1), Fos:Jun (AP-1), Klf13, Maf, Yy1, Ets1, Pou2f1 (Oct1), Pou2f2 (Oct2), Batf, Satb1, Irf4, Smarca4, and Stat6 positively regulate expression of Il4 BibTex
2025-12-27 R-MMU-9978103 Gata3, Chd4, Ep300, and Nfatc2 bind the Il13 gene BibTex
2025-12-27 R-MMU-9978121 Gata3, Chd4, Ep300, Nfatc2, Yy1, Ets1, Pou2f1 (Oct1), Pou2f2 (Oct2), Batf, Satb1, Irf4, Smarca4, and Stat6 positively regulate expression of Il13 BibTex
2025-12-27 R-MMU-9978124 Gata3 binds the Il5 gene BibTex
2025-12-27 R-MMU-9978105 Gata3 regulates the Il5 gene BibTex
2025-12-27 R-MMU-9978112 Gata3, Chd4, and the NuRD complex bind the Ifng gene BibTex
2025-12-24 R-MMU-9977991 Stat6, Nfatc2, and Nicd1,2 positiively regulate expression of Gata3 BibTex
2025-12-24 R-MMU-9977982 Gata3, Yy1, Ets1, Pou2f1, Pou2f2, Batf, Irf4, Satb1, Smarca4 and Stat6 bind the Locus Control Region in the Rad50 gene BibTex
2025-12-23 R-MMU-9977960 Stat6, Nfatc2 (Nfat1), and Nicd1,2 bind the Gata3 gene and cause displacement of repressor complexes (Prc1, Rbpj:NcoR) by activator complexes (Mll1, Rbpj:Nicd1,2) BibTex
2025-12-22 R-HSA-9977764 GATA3, YY1, ETS1, POU2F1 (OCT1), POU2F2 (OCT2), BATF, SATB1, IRF4, SMARCA4, and STAT6 bind the Locus Control Region (LCR) in the RAD50 gene BibTex
2025-12-11 R-HSA-9976381 GATA3, CHD4, EP300, and NFATC2 bind the IL13 gene BibTex
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Reviewed Pathways (11/11)
Date Identifier Pathway Reference
2025-06-02 R-HSA-1474244 Extracellular matrix organization BibTex
2025-06-02 R-HSA-1566977 Fibronectin matrix formation BibTex
2025-02-26 R-HSA-8953854 Metabolism of RNA BibTex
2024-05-23 R-HSA-5578749 Transcriptional regulation by small RNAs BibTex
2024-02-28 R-HSA-1266738 Developmental Biology BibTex
2022-08-06 R-HSA-9793242 SUMOylation of nuclear envelope proteins BibTex
2020-01-09 R-HSA-9673163 Oleoyl-phe metabolism BibTex
2015-10-04 R-HSA-3232118 SUMOylation of transcription factors BibTex
2014-01-31 R-HSA-5250941 Negative epigenetic regulation of rRNA expression BibTex
2013-01-12 R-HSA-2980736 Peptide hormone metabolism BibTex
2011-08-18 R-HSA-1433617 Regulation of signaling by NODAL BibTex
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Reviewed Reactions (15/60)
Date Identifier Reaction Reference
2026-02-28 R-MMU-9978110 Gata3, Chd4, Ep300, p-S243-Nfatc2 (p-S243-Nfat1), Fos:Jun (AP-1), Klf13, and Maf bind the Il4 gene BibTex
2026-02-28 R-MMU-9978102 Gata3, Chd4, Ep300, Nfatc2 (Nfat1), Fos:Jun (AP-1), Klf13, Maf, Yy1, Ets1, Pou2f1 (Oct1), Pou2f2 (Oct2), Batf, Satb1, Irf4, Smarca4, and Stat6 positively regulate expression of Il4 BibTex
2025-06-08 R-HSA-450466 AUF1:mRNA complex is degraded BibTex
2025-06-08 R-HSA-1168640 Ubiquitinated IkB is degraded BibTex
2025-06-02 R-HSA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA BibTex
2025-06-02 R-HSA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed BibTex
2025-06-02 R-HSA-2213248 Transport of antigen loaded MHC II molecules to surface BibTex
2025-06-02 R-HSA-6782443 QTRT1:QTRTD1 exchanges guanine for queuine at guanosine-34 of tRNA(Asn),tRNA(Asp),tRNA(His),tRNA(Tyr) yielding queuosine-34 tRNA(Asn),tRNA(Asp),tRNA(His),tRNA(Tyr) BibTex
2025-06-02 R-HSA-6787567 TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) BibTex
2024-05-23 R-HSA-877198 P2X7 mediates membrane pores that include pannexin-1 BibTex
2024-02-28 R-HSA-9024159 FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe) BibTex
2024-02-28 R-HSA-9024161 FTSJ1 2'-O-methylates guanosine-34 in tRNA(Phe) BibTex
2023-05-12 R-HSA-9820538 MSGN1 binds the TBX6 gene BibTex
2023-05-12 R-MMU-9820540 Msgn1 binds the Tbx6 gene BibTex
2023-05-12 R-HSA-9824181 Expression of LFNG in presomitic mesoderm BibTex
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