Bruce May

 ORCID
https://orcid.org/0000-0001-5193-0855
Project
Reactome
Affiliation
Cold Spring Harbor Laboratory
Authored Pathways (15/224)
Date Identifier Pathway Reference
2023-09-24 R-HSA-9845323 Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) BibTex
2023-09-11 R-HSA-9843940 Regulation of endogenous retroelements by KRAB-ZFP proteins BibTex
2023-09-11 R-HSA-9843970 Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex BibTex
2023-08-26 R-HSA-9842860 Regulation of endogenous retroelements BibTex
2023-07-14 R-HSA-9840373 Cellular response to mitochondrial stress BibTex
2023-06-18 R-HSA-9837999 Mitochondrial protein degradation BibTex
2023-06-08 R-HSA-9837092 FASTK family proteins regulate processing and stability of mitochondrial RNAs BibTex
2023-05-28 R-HSA-9836573 Mitochondrial RNA degradation BibTex
2023-05-10 R-HSA-9834899 Specification of the neural plate border BibTex
2023-04-10 R-HSA-9832991 Formation of the posterior neural plate BibTex
2023-03-26 R-HSA-9831926 Nephron development BibTex
2023-03-12 R-HSA-9830674 Formation of the ureteric bud BibTex
2023-03-08 R-HSA-9830369 Kidney development BibTex
2023-03-08 R-HSA-9830364 Formation of the nephric duct BibTex
2023-02-08 R-HSA-9827857 Specification of primordial germ cells BibTex
Authored Reactions (15/2,395)
Date Identifier Reaction Reference
2023-12-23 R-MMU-9856818 Mphosph8 of the HUSH complex bound to retroelement chromatin binds Zcchc8 of the NEXT complex BibTex
2023-09-24 R-HSA-9845308 DNMT3A:DNMT3L in nascent RNA transcript:MeR-PIWIL4:2'-O-methyl-piRNA:SPOCD1:DNMT3A:DNMT3L methylates cytosine in DNA BibTex
2023-09-24 R-MMU-9845305 Dnmt3a:Dnmt3l in nascent RNA transcript:MeR-Piwil4:2'-O-methyl-piRNA:Spocd11:Dnmt3a:Dnmt3l methylates cytosine in DNA BibTex
2023-09-17 R-HSA-9844716 MPHOSPH8 of the HUSH complex bound to retroelement chromatin binds ZCCHC8 of the NEXT complex BibTex
2023-09-12 R-HSA-9844111 EHMT1,EHMT2 trimethylates lysine-16 of ATF7IP BibTex
2023-09-12 R-MMU-9844112 Ehmt1,Ehmt2 trimethylates lysine-16 of Atf7ip BibTex
2023-09-12 R-MMU-9844103 me3-K16-Atf7ip binds Mphosph8 (Mpp8) BibTex
2023-09-11 R-HSA-9843990 HUSH complex binds LINE1 (L1) RNA BibTex
2023-09-11 R-HSA-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) BibTex
2023-09-11 R-HSA-9843993 me3-K16-ATF7IP:SETDB1 and MORC2 bind MPHOSPH8 (MPP8) in HUSH complex:L1 RNA BibTex
2023-09-11 R-HSA-9843927 me3-K16-ATF7IP:SETDB1 and MORC2 bind MPHOSPH8 (MPP8) in HUSH complex:L1HS,L1PA2,3 heterochromatin BibTex
2023-09-11 R-HSA-9844015 MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin BibTex
2023-09-11 R-HSA-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome BibTex
2023-09-08 R-NUL-9844000 TRIM28 (KAP1) binds CHD3 (Mi-2alpha) BibTex
2023-09-08 R-HSA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin BibTex
Reviewed Pathways (9/9)
Date Identifier Pathway Reference
2024-05-23 R-HSA-5578749 Transcriptional regulation by small RNAs BibTex
2024-02-28 R-HSA-1266738 Developmental Biology BibTex
2024-02-26 R-HSA-2022377 Metabolism of Angiotensinogen to Angiotensins BibTex
2022-08-06 R-HSA-9793242 SUMOylation of nuclear envelope proteins BibTex
2020-01-09 R-HSA-9673163 Oleoyl-phe metabolism BibTex
2015-10-04 R-HSA-3232118 SUMOylation of transcription factors BibTex
2014-01-31 R-HSA-5250941 Negative epigenetic regulation of rRNA expression BibTex
2013-01-12 R-HSA-2980736 Peptide hormone metabolism BibTex
2011-08-18 R-HSA-1433617 Regulation of signaling by NODAL BibTex
Reviewed Reactions (15/51)
Date Identifier Reaction Reference
2024-05-23 R-HSA-877198 P2X7 mediates membrane pores that include pannexin-1 BibTex
2024-02-28 R-HSA-9024159 FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe) BibTex
2024-02-28 R-HSA-9024161 FTSJ1 2'-O-methylates guanosine-34 in tRNA(Phe) BibTex
2023-05-12 R-HSA-9820538 MSGN1 binds the TBX6 gene BibTex
2023-05-12 R-MMU-9820540 Msgn1 binds the Tbx6 gene BibTex
2023-05-12 R-HSA-9824181 Expression of LFNG in presomitic mesoderm BibTex
2023-05-12 R-HSA-9824182 RBPJ:NICD1 and MSGN1 bind the LFNG gene BibTex
2023-05-12 R-MMU-9824231 Rbpj:Nicd and Msgn1 bind the Lfng gene BibTex
2023-05-12 R-MMU-9824254 Expression of Lfng in presomitic mesoderm BibTex
2023-05-12 R-HSA-9824222 HES7 binds the HES7 gene BibTex
2023-05-12 R-HSA-9824268 Expression of HES7 in presomitic mesoderm BibTex
2023-05-12 R-HSA-9824266 LEF1:CTNNB1, NICD1 (NOTCH1) and TBX6 bind the HES7 gene in presomitic mesoderm BibTex
2023-05-12 R-MMU-9824206 Lef1:Ctnnb1, Nicd (Notch), and Tbx6 bind the Hes7 gene in presomitic mesoderm BibTex
2023-05-12 R-MMU-9824253 Expression of Hes7 in presomitic mesoderm BibTex
2023-05-12 R-MMU-9824278 Hes7 binds the Hes7 gene BibTex
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