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monoSUMO1-K33 GATAD2B [nucleoplasm]
Stable Identifier
R-HSA-9940398
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Transcriptional repressor p66-beta, P66B_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q8IYF3 TEX11
Expand all
Chromatin organization (Homo sapiens)
ATP-dependent chromatin remodelers (Homo sapiens)
CHD chromatin remodelers (Homo sapiens)
CHD3, CHD4, CHD5 subfamily (Homo sapiens)
NuRD complex assembly (Homo sapiens)
GATAD2B is SUMOylated (Homo sapiens)
monoSUMO1-K33 GATAD2B [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8WXI9 GATAD2B
Gene Names
GATAD2B, KIAA1150
Chain
chain:1-593
Reference Genes
BioGPS Gene:57459 GATAD2B
COSMIC - genes:GATAD2B GATAD2B
CTD Gene:57459 GATAD2B
dbSNP Gene:57459 GATAD2B
ENSEMBL:ENSG00000143614 GATAD2B
HGNC:30778 GATAD2B
KEGG:hsa:57459 GATAD2B
Monarch:57459 GATAD2B
NCBI Gene:57459 GATAD2B
OMIM:614998 GATAD2B
UCSC:Q8WXI9 GATAD2B
Reference Transcript
RefSeq:NM_020699.4 GATAD2B
RefSeq:XM_047426117.1 GATAD2B
RefSeq:XM_054337815.1 GATAD2B
Other Identifiers
11724893_at
11724894_at
11724895_at
16693546
225393_PM_at
225393_at
238076_PM_at
238076_at
2436227
2436229
2436230
2436231
2436232
2436233
2436234
2436236
2436237
2436238
2436239
2436240
2436241
2436242
2436243
2436244
2436245
2436247
2436248
2436269
2436274
2436275
2436276
2436277
46443_at
57459
64410_at
68606_at
7920341
A_19_P00324786
A_23_P386509
A_33_P3323822
GE53798
GO:0000122
GO:0000781
GO:0000785
GO:0003677
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0006325
GO:0006338
GO:0006355
GO:0008270
GO:0016581
GO:0016607
GO:0031492
GO:0032991
GO:0042659
GO:0043565
GO:0045892
GO:0045893
GO:0046872
GO:2000736
HMNXSV003023369
Hs.44772.0.A1_3p_at
Hs.4779.1.A1_3p_at
ILMN_1766359
PH_hs_0000486
TC01003278.hg
Participates
as an output of
GATAD2B is SUMOylated (Homo sapiens)
as a member of
SUMO1-GATAD2A, SUMO1-GATAD2B [nucleoplasm] (Homo sapiens)
Other forms of this molecule
GATAD2B [nucleoplasm]
Inferred To
dcp-66 [nucleoplasm]
(Caenorhabditis elegans)
gatad2b [nucleoplasm]
(Xenopus tropicalis)
Gatad2b [nucleoplasm]
(Mus musculus)
Gatad2b [nucleoplasm]
(Rattus norvegicus)
GATAD2B [nucleoplasm]
(Bos taurus)
GATAD2B [nucleoplasm]
(Canis familiaris)
GATAD2B [nucleoplasm]
(Gallus gallus)
GATAD2B [nucleoplasm]
(Sus scrofa)
simj [nucleoplasm]
(Drosophila melanogaster)
Modified Residues
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 33
Coordinate
33
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
RefSeq
XP_047282073.1
,
XP_054193790.1
,
NP_065750.1
OpenTargets
ENSG00000143614
ENSEMBL
ENSP00000489184
,
ENST00000576342
,
ENSP00000458280
,
ENSG00000261992
,
ENSP00000357644
,
ENSG00000143614
,
ENST00000368655
,
ENST00000634544
GeneCards
GATAD2B
HPA
ENSG00000143614-GATAD2B
PRO
Q8WXI9
Pharos - Targets
Q8WXI9
GlyGen
Q8WXI9
Orphanet
GATAD2B
Interactors (48)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13547 HDAC1
2
HDAC1 [nucleoplasm]
(R-HSA-205021)
monoSUMO1-K444,K476-HDAC1 [nucleoplasm]
(R-HSA-4616030)
0.892
11
UniProt:Q92769 HDAC2
2
HDAC2 [nucleoplasm]
(R-HSA-205135)
monoSUMO1-K462-HDAC2 [nucleoplasm]
(R-HSA-4615958)
0.837
7
UniProt:Q16576 RBBP7
1
RBBP7 [nucleoplasm]
(R-HSA-212227)
0.788
8
UniProt:Q09028 RBBP4
1
RBBP4 [nucleoplasm]
(R-HSA-212223)
0.788
7
UniProt:O14519 CDK2AP1
1
CDK2AP1 [nucleoplasm]
(R-HSA-9940397)
0.788
7
UniProt:O95983 MBD3
1
MBD3 [nucleoplasm]
(R-HSA-4657010)
0.742
7
UniProt:O43741 PRKAB2
3
PRKAB2 [cytosol]
(R-HSA-200413)
PRKAB2 [nucleoplasm]
(R-HSA-164096)
PRKAB2 [endoplasmic reticulum lumen]
(R-HSA-9931271)
0.666
4
UniProt:Q13077 TRAF1
3
TRAF1 [cytosol]
(R-HSA-5634163)
TRAF1(1-163) [cytosol]
(R-HSA-5634199)
TRAF1(164-416) [cytosol]
(R-HSA-5634204)
0.666
4
UniProt:P52294 KPNA1
2
KPNA1 [cytosol]
(R-HSA-180612)
KPNA1 [nucleoplasm]
(R-HSA-188865)
0.643
3
UniProt:O94776 MTA2
1
MTA2 [nucleoplasm]
(R-HSA-4657009)
0.643
6
UniProt:Q9NRI5 DISC1
0.632
3
UniProt:O95365 ZBT7A
0.567
4
UniProt:P14373 TRIM27
2
TRIM27 [cytosol]
(R-HSA-8851002)
TRIM27 [nucleoplasm]
(R-HSA-2997690)
0.556
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:Q14192 FHL2
1
FHL2 [nucleoplasm]
(R-HSA-561161)
0.556
3
UniProt:P55273 CDKN2D
1
CDKN2D [cytosol]
(R-HSA-182580)
0.556
3
UniProt:P0C264 SBK3
0.556
3
UniProt:Q86UR1-2 NOXA1
0.556
3
UniProt:Q9Y4H4 GPSM3
1
GPSM3 [cytosol]
(R-HSA-8949486)
0.556
3
UniProt:Q9Y5B8 NME7
1
NME7 [cytosol]
(R-HSA-6806880)
0.556
3
UniProt:Q8N6Y0 USBP1
0.556
3
UniProt:Q8IYF3 TEX11
0.556
3
UniProt:Q13137 CACO2
0.556
3
UniProt:Q8NHQ1 CEP70
1
CEP70 [cytosol]
(R-HSA-380257)
0.556
3
UniProt:Q8N5A5-2 ZGPAT
0.556
3
UniProt:Q96KN7 RPGR1
0.556
3
UniProt:Q9NPG2 NGB
1
NGB [cytosol]
(R-HSA-5216004)
0.556
3
UniProt:P15056 BRAF
20
BRAF(1-380)-MACF1(600-7388)fusion [cytosol]
(R-HSA-6802402)
p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol]
(R-HSA-6802536)
BRAF E501G [cytosol]
(R-HSA-9651132)
BRAF D594N [cytosol]
(R-HSA-6802299)
BRAF D638E [cytosol]
(R-HSA-9651125)
BRAF G596R [cytosol]
(R-HSA-6802385)
BRAF D594V [cytosol]
(R-HSA-6802305)
BRAF G596V [cytosol]
(R-HSA-9651138)
BRAF G466E [cytosol]
(R-HSA-6802374)
BRAF D594G [cytosol]
(R-HSA-6802295)
BRAF L505H [cytosol]
(R-HSA-9648845)
BRAF F595L [cytosol]
(R-HSA-6802316)
BRAF L597V [cytosol]
(R-HSA-6802397)
BRAF G464E [cytosol]
(R-HSA-6802369)
BRAF N581D [cytosol]
(R-HSA-9651152)
BRAF E586K [cytosol]
(R-HSA-6802308)
BRAF V600K [cytosol]
(R-HSA-6802502)
BRAF A246P [cytosol]
(R-HSA-9651123)
BRAF G469V [cytosol]
(R-HSA-9648620)
BRAF T244P [cytosol]
(R-HSA-9651165)
0.553
3
UniProt:Q9HCI5 MAGE1
0.527
2
UniProt:P68400 CSNK2A1
2
CSNK2A1 [cytosol]
(R-HSA-201713)
CSNK2A1 [nucleoplasm]
(R-HSA-6805057)
0.527
2
UniProt:Q8TDI0 CHD5
1
CHD5 [nucleoplasm]
(R-HSA-9940392)
0.527
4
UniProt:Q9UHF7 TRPS1
0.527
2
UniProt:P19784 CSNK2A2
2
CSNK2A2 [cytosol]
(R-HSA-201721)
CSNK2A2 [nucleoplasm]
(R-HSA-6805065)
0.527
2
UniProt:Q12873 CHD3
2
CHD3 [nucleoplasm]
(R-HSA-4657012)
monoSUMO1-K1971-CHD3 [nucleoplasm]
(R-HSA-8956372)
0.527
5
UniProt:Q9H3M7 TXNIP
2
TXNIP [cytosol]
(R-HSA-1250246)
TXNIP [nucleoplasm]
(R-HSA-9617747)
0.527
2
UniProt:Q14839 CHD4
1
CHD4 [nucleoplasm]
(R-HSA-3702078)
0.527
5
UniProt:O96006 ZBED1
1
ZBED1 [nucleoplasm]
(R-HSA-8956376)
0.527
2
UniProt:Q13330 MTA1
2
MTA1 [nucleoplasm]
(R-HSA-3465550)
polySUMO2,3-K509-MTA1 [nucleoplasm]
(R-HSA-3465537)
0.527
4
UniProt:Q9UBB5 MBD2
1
MBD2 [nucleoplasm]
(R-HSA-427367)
0.527
4
UniProt:Q15274 QPRT
1
QPRT [cytosol]
(R-HSA-197212)
0.527
2
UniProt:Q8WWY6 MBD3L1
1
MBD3L1 [nucleoplasm]
(R-HSA-9940391)
0.527
3
UniProt:Q86UZ6 ZBT46
0.527
2
UniProt:Q9P2Y4 ZN219
0.527
4
UniProt:Q96KM6 ZNF512B
1
ZNF512B [cytosol]
(R-HSA-9715175)
0.527
3
UniProt:Q9HCH3 CPNE5
0.527
2
UniProt:Q93045 STMN2
1
STMN2 [cytosol]
(R-HSA-9696513)
0.527
2
UniProt:Q9BTC8 MTA3
1
MTA3 [nucleoplasm]
(R-HSA-4657013)
0.527
4
UniProt:Q17R98 ZNF827
1
ZNF827 [nucleoplasm]
(R-HSA-9941663)
0.499
2
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