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ZBED1 [nucleoplasm]
Stable Identifier
R-HSA-8956376
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Zinc finger BED domain-containing protein 1, ZBED1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of chromatin organization proteins (Homo sapiens)
ZBED1 (DREF) SUMOylates CHD3 with SUMO1 (Homo sapiens)
ZBED1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O96006 ZBED1
Gene Names
ZBED1, ALTE, DREF, hDREF, KIAA0785, TRAMP
Chain
chain:1-694
Reference Genes
BioGPS Gene:9189 ZBED1
COSMIC (genes):ZBED1 ZBED1
CTD Gene:9189 ZBED1
dbSNP Gene:9189 ZBED1
ENSEMBL:ENSG00000214717 ZBED1
ENSEMBL_homo_sapiens_GENE:ENSG00000214717.12 ZBED1
ENSEMBL_homo_sapiens_GENE:ENSG00000292345.1 ZBED1
HGNC:447 ZBED1
KEGG Gene (Homo sapiens):9189 ZBED1
Monarch:9189 ZBED1
NCBI Gene:9189 ZBED1
OMIM:300178 ZBED1
UCSC:O96006 ZBED1
Reference Transcript
RefSeq:NM_001171135.1 ZBED1
RefSeq:NM_001171136.1 ZBED1
RefSeq:NM_004729.3 ZBED1
Other Identifiers
11718794_at
11749013_x_at
1554821_PM_a_at
1554821_a_at
203043_PM_at
203043_at
39168_at
3997567
3997568
3997569
3997570
3997571
3997574
3997575
3997576
4033358
4033359
4033360
4033361
4033362
4033364
4033365
44978_at
8171139
8177029
9189
A_23_P217507
A_32_P86623
A_33_P3398840
GE53488
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0003677
GO:0003712
GO:0003713
GO:0003824
GO:0005515
GO:0005634
GO:0005635
GO:0005654
GO:0005694
GO:0005813
GO:0005815
GO:0005856
GO:0006351
GO:0006355
GO:0006357
GO:0016605
GO:0016740
GO:0016925
GO:0019789
GO:0031965
GO:0036211
GO:0042802
GO:0043226
GO:0043565
GO:0044828
GO:0045944
GO:0046872
GO:0046983
GO:0061665
GO:0140096
GO:0140110
GO:1990466
GO:1990837
HMNXSV003034179
Hs2.9933.2.S1_3p_x_at
ILMN_1694466
PH_hs_0026388
TC0Y000287.hg
g4759257_3p_at
Inferred To
ZBED1 [nucleoplasm]
(Caenorhabditis elegans)
ZBED1 [nucleoplasm]
(Sus scrofa)
Homologues of ZBED1 [nucleoplasm]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001164607.1
,
NP_001164606.1
,
NP_004720.1
OpenTargets
ENSG00000214717
GeneCards
O96006
HPA
ENSG00000214717-ZBED1
Ensembl
ENSP00000498725
,
ENST00000381218
,
ENST00000652001
,
ENSP00000370616
,
ENST00000381222
,
ENST00000381223
,
ENSP00000370620
,
ENSP00000370621
,
ENSG00000214717
PRO
O96006
Pharos - Targets
O96006
PDB
2CT5
Interactors (56)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NX04 AIRIM
0.781
7
UniProt:Q8TCA0 LRC20
0.718
6
UniProt:Q5JVL4 EFHC1
0.718
6
UniProt:Q7KZS0 Q7KZS0
0.718
6
UniProt:P07602 PSAP
11
PSAP(60-142) [extracellular region]
(R-HSA-351338)
PSAP(17-524) [plasma membrane]
(R-HSA-6806262)
PSAP(17-524) [azurophil granule membrane]
(R-HSA-6799212)
PSAP(311-391) [lysosomal lumen]
(R-HSA-9851355)
PSAP(405-486) [lysosomal lumen]
(R-HSA-9840328)
PSAP(311-391) [lysosomal membrane]
(R-HSA-1605602)
PSAP(60-142) [lysosomal lumen]
(R-HSA-351333)
PSAP [lysosomal lumen]
(R-HSA-9840325)
PSAP(195-273) [lysosomal lumen]
(R-HSA-9840336)
PSAP(?-?) [extracellular region]
(R-HSA-5336190)
PSAP(326-340) [extracellular region]
(R-HSA-5336179)
0.666
4
UniProt:O60341 KDM1A
1
KDM1A [nucleoplasm]
(R-HSA-996769)
0.666
4
UniProt:O96006 ZBED1
1
ZBED1 [nucleoplasm]
(R-HSA-8956376)
0.666
4
UniProt:P10644 PRKAR1A
4
PRKAR1A(1-183)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9713476)
PRKAR1A(1-183)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9713471)
PRKAR1A [ciliary base]
(R-HSA-5610408)
PRKAR1A [cytosol]
(R-HSA-57836)
0.659
3
UniProt:Q8N5I4 DHRSX
0.589
3
UniProt:Q8IYE1 CCD13
0.556
3
UniProt:Q8N7C3 TRIMM
0.556
3
UniProt:Q96JP2 MY15B
0.556
3
UniProt:Q16385 SSX2
0.556
3
UniProt:Q9BVV2 FND11
0.556
3
UniProt:P32502
1
GCD7 [cytosol]
(R-SCE-72519)
0.556
3
UniProt:P80188 LCN2
2
LCN2 [specific granule lumen]
(R-HSA-6799614)
LCN2 [extracellular region]
(R-HSA-5215934)
0.556
3
UniProt:Q9NPJ1 MKKS
1
MKKS [cytosol]
(R-HSA-5624086)
0.556
3
UniProt:A8K5H9 A8K5H9
0.556
3
UniProt:Q9H8Y8 GORASP2
2
GORASP2 [Golgi membrane]
(R-HSA-2422385)
p-T222,T225-GORASP2 [Golgi membrane]
(R-HSA-2422965)
0.556
3
UniProt:Q9BVM4 GGACT
0.556
3
UniProt:Q96HA8 NTAQ1
0.556
3
UniProt:P56282 POLE2
1
POLE2 [nucleoplasm]
(R-HSA-68482)
0.556
3
UniProt:P40454 PTPA1
0.556
3
UniProt:P17157 PHO85
0.556
3
UniProt:Q9UBB6 NCDN
0.556
3
UniProt:P0DI81-3 TRAPPC2
0.556
3
UniProt:Q9H5Z6-2 FAM124B
0.556
3
UniProt:P38340 NTM1
0.556
3
UniProt:Q13671 RIN1
1
RIN1 [cytosol]
(R-HSA-8875287)
0.556
3
UniProt:Q16543 CDC37
1
CDC37 [cytosol]
(R-HSA-1221609)
0.556
3
UniProt:Q9UBT7 CTNL1
0.556
3
UniProt:Q13131 PRKAA1
3
p-T183-PRKAA1 [cytosol]
(R-HSA-380964)
PRKAA1 [cytosol]
(R-HSA-380935)
p-T183-PRKAA1 [nucleoplasm]
(R-HSA-2151206)
0.556
3
UniProt:Q9Y2J4-4 AMOTL2
0.556
3
UniProt:Q8TBB1 LNX1
1
LNX1 [cytosol]
(R-HSA-8851641)
0.556
3
UniProt:Q07887 LDB18
0.556
3
UniProt:Q5W5X9-3 TTC23
0.556
3
UniProt:P39518
1
ACSL5 [endoplasmic reticulum membrane]
(R-SCE-165011)
0.556
3
UniProt:Q9BVG8-5 KIFC3
0.556
3
UniProt:O15479 MAGB2
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.556
3
UniProt:O75928 PIAS2
1
PIAS2 [nucleoplasm]
(R-HSA-2993787)
0.556
3
UniProt:Q9Y5K5 UCHL5
2
UCHL5 [cytosol]
(R-HSA-1629778)
UCHL5 [nucleoplasm]
(R-HSA-5689584)
0.556
3
UniProt:O75604 USP2
2
USP2 [cytosol]
(R-HSA-5212661)
USP2 [nucleoplasm]
(R-HSA-5689946)
0.556
3
UniProt:O15160 POLR1C
2
POLR1C [nucleoplasm]
(R-HSA-63498)
POLR1C [cytosol]
(R-HSA-1964454)
0.556
3
UniProt:P25325 MPST
2
CysS248-MPST [mitochondrial matrix]
(R-HSA-9034913)
MPST [mitochondrial matrix]
(R-HSA-9012720)
0.556
3
UniProt:Q9UI95 MAD2L2
1
MAD2L2 [nucleoplasm]
(R-HSA-59092)
0.556
3
UniProt:P26367 PAX6
1
PAX6 [nucleoplasm]
(R-HSA-3009044)
0.556
3
UniProt:O15287 FANCG
2
FANCG [nucleoplasm]
(R-HSA-419532)
FANCG [cytosol]
(R-HSA-420788)
0.553
2
UniProt:Q9Y4P9 SPEF1
0.547
2
UniProt:O94776 MTA2
1
MTA2 [nucleoplasm]
(R-HSA-4657009)
0.527
2
UniProt:Q05048 CSTF1
1
CSTF1 [nucleoplasm]
(R-HSA-72001)
0.527
2
UniProt:O75629 CREG1
2
CREG1 [extracellular region]
(R-HSA-6806210)
CREG1 [azurophil granule lumen]
(R-HSA-6799148)
0.527
2
UniProt:P50613 CDK7
1
CDK7 [nucleoplasm]
(R-HSA-69218)
0.527
2
UniProt:Q96P53 WDFY2
0.527
2
UniProt:Q9H609 ZN576
0.527
3
UniProt:Q8WXI9 GATAD2B
1
GATAD2B [nucleoplasm]
(R-HSA-3702079)
0.527
2
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