ALK D1203N [plasma membrane]

Stable Identifier
R-HSA-9701838
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
ALK tyrosine kinase receptor, ALK_HUMAN
ALK D1203N [plasma membrane] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
21596819 Anaplastic thyroid cancers harbor novel oncogenic mutations of the ALK gene

Xing, M, Murugan, AK

Cancer Res. 2011
External Reference Information
External Reference
Gene Names
ALK
Chain
signal peptide:1-18, chain:19-1620
Reference Transcript
Other Identifiers
11740853_a_at
11750678_a_at
16896049
208211_PM_s_at
208211_s_at
208212_PM_s_at
208212_s_at
238
2546410
2546411
2546412
2546413
2546414
2546415
2546416
2546417
2546418
2546420
2546423
2546424
2546429
2546431
2546432
2546433
2546434
2546436
2546437
2546439
2546440
2546441
2546442
2546444
2546450
2546458
2546459
2546464
2546468
2546470
2546471
2546472
2546479
2546492
2546493
2546508
2546511
2546512
2546542
2546543
38543_at
451_at
66494_at
8051241
A_23_P10091
A_23_P324304
GE81380
GO:0000166
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005886
GO:0006351
GO:0006355
GO:0006468
GO:0006629
GO:0007165
GO:0007169
GO:0007399
GO:0007420
GO:0008201
GO:0012501
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0021766
GO:0023052
GO:0030154
GO:0030298
GO:0030534
GO:0032991
GO:0036211
GO:0036269
GO:0038083
GO:0042127
GO:0042802
GO:0042981
GO:0043226
GO:0043235
GO:0045664
GO:0046777
GO:0048666
GO:0048856
GO:0050995
GO:0051092
GO:0060089
GO:0060159
GO:0070062
GO:0090648
GO:0097009
GO:0098772
GO:0140096
GO:1900006
HMNXSV003058035
ILMN_1753135
PH_hs_0024837
TC02001708.hg
U66559_at
g1848243_3p_a_at
Participates
Other forms of this molecule
Modified Residues
Name
L-aspartic acid 1203 replaced with L-asparagine
Coordinate
1203
PsiMod
A protein modification that effectively removes or replaces an L-aspartic acid.
A protein modification that effectively converts a source amino acid residue to an L-asparagine.
Disease
Name Identifier Synonyms
non-small cell lung carcinoma DOID:3908 Non-small cell lung cancer (disorder), NSCLC, NSCLC
lung adenocarcinoma DOID:3910 nonsmall cell adenocarcinoma
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Investigational
ZINC - Metabolites
GeneCards
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (11)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q6UXT8 FAM150A  1 0.655 7
 ChEBI:64310 CRIZOTINIB      0.59 9
 UniProt:P29353 SHC1  5 0.569 3
 ChEBI:62268 CH5424802      0.558 3
 UniProt:Q6UX46 FAM150B  2 0.556 5
 UniProt:P23471 PTPRZ1  2 0.544 2
 UniProt:P08238 HSP90AB1  6 0.524 2
 UniProt:P07949 RET  2 0.499 2
 UniProt:P29317 EPHA2  2 0.483 2
 UniProt:P29376 LTK  2 0.483 2
 UniProt:Q9Y2U8 LEMD3  4 0.483 2
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