Reactome | ALKAL2 [extracellular region]

ALKAL2 [extracellular region]

Stable Identifier

R-HSA-9842580

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

FAM150B, fullName evidence="12"ALK and LTK ligand 2, ALKL2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6UX46 FAM150B

Gene Names

FAM150B, UNQ542/PRO1097, ALKAL2

Chain

signal peptide:1-24, chain:25-152

Reference Genes

BioGPS Gene:285016 FAM150B

COSMIC (genes):ALKAL2 FAM150B

CTD Gene:285016 FAM150B

dbSNP Gene:285016 FAM150B

ENSEMBL:ENSG00000189292 FAM150B

HGNC:27683 FAM150B

Monarch:285016 FAM150B

NCBI Gene:285016 FAM150B

OMIM:619671 FAM150B

UCSC:Q6UX46 FAM150B

Reference Transcript

Other Identifiers

11729445_at

16893748

238018_PM_at

238018_at

2537172

2537175

2537176

2537180

2537181

2537182

2537183

2537184

2537185

2537186

2537187

2537188

2537191

2537196

285016

77135_at

8049990

87161_s_at

87162_r_at

A_24_P561341

A_33_P3320197

GE810975

GO:0005125

GO:0005515

GO:0005576

GO:0005615

GO:0005886

GO:0007165

GO:0007169

GO:0010976

GO:0030297

GO:0030298

GO:0030971

GO:0048018

GO:0070374

GO:0070378

GO:0098772

HMNXSV003029522

HMNXSV003034364

Hs.213923.0.A1_3p_at

ILMN_2089752

TC02001496.hg

Participates

as a member of

ALKAL1,2 [extracellular region] (Homo sapiens)

Other forms of this molecule

HC-ALKAL2 [extracellular region]

Inferred To

alkal2 [extracellular region] (Xenopus tropicalis)

Alkal2 [extracellular region] (Mus musculus)

Alkal2 [extracellular region] (Rattus norvegicus)

alkal2b [extracellular region] (Danio rerio)

FAM150B [extracellular region] (Gallus gallus)

Cross References

ENSEMBL

ENST00000403610, ENSP00000384604

OpenTargets

ENSG00000189292

HPA

ENSG00000189292-ALKAL2

PRO

Q6UX46

Pharos - Targets

Q6UX46

PDB

7LS0, 7N00, 7NWZ, 7MZX

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UM73 ALK	20	p-7Y ALK T1087I [plasma membrane] (R-HSA-9723885) p-7Y ALK R1061Q [plasma membrane] (R-HSA-9723884) p-7Y ALK L1196M [plasma membrane] (R-HSA-9700464) p-7Y ALK M1166R [plasma membrane] (R-HSA-9700477) p-Y ALK S1206C [plasma membrane] (R-HSA-9715292) p- 7Y ALK L1122V [plasma membrane] (R-HSA-9715294) p-7Y ALK E1384K [plasma membrane] (R-HSA-9715285) p-7Y ALK L1196Q [plasma membrane] (R-HSA-9700476) p-7Y ALK V1180L [plasma membrane] (R-HSA-9715289) p-7Y ALK G1201R [plasma membrane] (R-HSA-9701860) p-7Y ALK I1171T [plasma membrane] (R-HSA-9700489) p-7Y ALK R1275L [plasma membrane] (R-HSA-9699800) p-7Y ALK F1174C [plasma membrane] (R-HSA-9699821) p-7Y ALK F1174V [plasma membrane] (R-HSA-9699921) p-7Y ALK M1166N [plasma membrane] (R-HSA-9723299) p-7Y ALK M1166T [plasma membrane] (R-HSA-9700486) p-7Y ALK Y1239H [plasma membrane] (R-HSA-9715290) p-7Y ALK R1275* [plasma membrane] (R-HSA-9699915) p-7Y ALK I1171S [plasma membrane] (R-HSA-9714063) p-7Y ALK G1128S [plasma membrane] (R-HSA-9700462)	0.556	5