hC36,103-HSF1 [cytosol]

Stable Identifier
R-HSA-4793916
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Heat shock transcription factor 1, HSTF 1, Heat shock factor protein 1
Icon
hC36,103-HSF1 [cytosol] icon
hC36,103-HSF1 [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q00613 HSF1
Gene Names
HSF1, HSTF1
Chain
chain:1-529
Reference Genes
BioGPS Gene:3297 HSF1
COSMIC (genes):HSF1 HSF1
CTD Gene:3297 HSF1
dbSNP Gene:3297 HSF1
ENSEMBL:ENSG00000185122 HSF1
HGNC:5224 HSF1
KEGG:hsa:3297 HSF1
Monarch:3297 HSF1
NCBI Gene:3297 HSF1
OMIM:140580 HSF1
UCSC:Q00613 HSF1
Reference Transcript
Other Identifiers
11723695_s_at
17073759
202344_PM_at
202344_at
213756_PM_s_at
213756_s_at
244_at
3120359
3120360
3120361
3120362
3120365
3120366
3120384
3120385
3120386
3120387
3120388
3120389
3120390
3120391
3120392
3120393
3120394
3120395
3120396
3120397
3120398
3120399
3120400
3120401
3120402
3120403
3120404
3120405
3120407
3120408
3120409
3120410
3120411
3120412
3120413
3297
40200_at
4049903
4049904
4049905
4049906
4049907
4049908
4049909
4049910
4049911
4049912
4049913
4049914
4049915
4049916
4049917
4049918
4049919
4049920
4049921
4049922
4049923
4049924
4049925
4049926
4049927
4049928
4049929
8148824
A_23_P253841
A_33_P3347932
A_33_P3347937
GE58037
GE84888
GO:0000122
GO:0000165
GO:0000775
GO:0000776
GO:0000785
GO:0000791
GO:0000792
GO:0000922
GO:0000976
GO:0000978
GO:0000981
GO:0001162
GO:0001227
GO:0001228
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006281
GO:0006355
GO:0006357
GO:0006397
GO:0006952
GO:0007584
GO:0010628
GO:0010629
GO:0010667
GO:0014070
GO:0014823
GO:0016071
GO:0016605
GO:0019901
GO:0031072
GO:0031333
GO:0031490
GO:0032355
GO:0033574
GO:0034605
GO:0034620
GO:0035865
GO:0042802
GO:0043200
GO:0043226
GO:0043565
GO:0045651
GO:0045931
GO:0045944
GO:0046982
GO:0048471
GO:0051028
GO:0051091
GO:0051879
GO:0061770
GO:0062029
GO:0065003
GO:0070301
GO:0071222
GO:0071230
GO:0071276
GO:0071280
GO:0071392
GO:0071407
GO:0071466
GO:0071478
GO:0071480
GO:0072738
GO:0090084
GO:0090261
GO:0097165
GO:0097431
GO:0097677
GO:0098847
GO:0101031
GO:0120162
GO:0140110
GO:0140296
GO:1900034
GO:1901652
GO:1902512
GO:1903936
GO:1904385
GO:1904843
GO:1904845
GO:1990837
GO:1990841
GO:1990904
GO:1990910
GO:1990911
GO:2001033
HMNXSV003007205
HMNXSV003011537
HMNXSV003033648
Hs.1499.1.S1_3p_a_at
ILMN_1665621
ILMN_1667060
ILMN_1679371
ILMN_1679867
ILMN_1718352
ILMN_1721700
M64673_at
PH_hs_0031748
TC08000849.hg
TC08002160.hg
g5031766_3p_at
g5031766_3p_x_at
Participates
as a component of
Other forms of this molecule
HSF1 [cytosol]
p-S326-hC36,103-HSF1 [nucleoplasm]
hC36,103-HSF1 [nucleoplasm]
Ac-K80-hC36,103-HSF1 [nucleoplasm]
p-S230-hC36,103-HSF1 [nucleoplasm]
HSF1 [nucleoplasm]
p-S303,307-HSF1 [cytosol]
p-S307-HSF1 [cytosol]
p-S303-HSF1 [cytosol]
p-S121-HSF1 [cytosol]
Inferred To
hC36,103-HSF1 [cytosol] (Dictyostelium discoideum)
hC36,103-HSF1 [cytosol] (Gallus gallus)
Hsf [cytosol] (Drosophila melanogaster)
Hsf1 [cytosol] (Mus musculus)
Hsf1 [cytosol] (Rattus norvegicus)
hsf-1 [cytosol] (Caenorhabditis elegans)
HSF1 [cytosol] (Bos taurus)
HSF1 [cytosol] (Canis familiaris)
HSF1 [cytosol] (Saccharomyces cerevisiae)
HSF1 [cytosol] (Sus scrofa)
hsf1 [cytosol] (Schizosaccharomyces pombe)
Modified Residues
Name
Inter-chain Crosslink via L-cystine (cross-link) at 103 and 36
Coordinate
103
PsiMod Name
L-cystine (cross-link)
PsiMod Definition
A protein modification that effectively cross-links two L-cysteine residues to form L-cystine.
Name
Inter-chain Crosslink via L-cystine (cross-link) at 36 and 103
Coordinate
36
PsiMod Name
L-cystine (cross-link)
PsiMod Definition
A protein modification that effectively cross-links two L-cysteine residues to form L-cystine.
Cross References
RefSeq
OpenTargets
ENSEMBL
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
GlyGen
PDB
ZINC - Metabolites
HPA
Pharos - Targets
ZINC - Predictions - Purchasable
Interactors (30)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q03933 HSF2      0.848 11
 UniProt:Q9NZL4 HPBP1      0.725 4
 UniProt:O00505 KPNA3  2 0.638 3
 UniProt:O00629 KPNA4  2 0.638 3
 UniProt:O95817 BAG3  1 0.638 3
 UniProt:P49137 MAPKAPK2  5 0.602 5
 UniProt:Q5VY09 IER5      0.589 3
 UniProt:Q00613 HSF1  11 0.571 2
 IntAct:EBI-25856799 CCSB      0.556 3
 UniProt:Q96CM3 RUSD4      0.556 3
 UniProt:P11684 UTER      0.556 3
 UniProt:Q6ZMY6-2 Q6ZMY62      0.556 3
 UniProt:Q8NFB2 T185A      0.556 3
 UniProt:Q9UNY5 ZN232      0.556 3
 UniProt:O14744 PRMT5  3 0.556 3
 UniProt:Q9UIH9 KLF15  1 0.556 3
 UniProt:Q13352 ITGB3BP  2 0.556 3
 UniProt:Q14693 LPIN1  3 0.556 3
 UniProt:Q8N4C8 MINK1  1 0.544 2
 UniProt:Q04759 PRKCQ  9 0.544 2
 UniProt:Q9ULV5 HSF4      0.527 2
 UniProt:P62258 YWHAE  1 0.527 2
 UniProt:P34931 HSPA1L  2 0.508 2
 UniProt:Q96SB8 SMC6  1 0.508 2
 UniProt:Q8NEH6 MNS1      0.508 2
 UniProt:Q8NET4 RTL9      0.508 2
 UniProt:O43683 BUB1  1 0.508 2
 UniProt:P53350 PLK1  4 0.508 2
 UniProt:Q15029 EFTUD2  1 0.508 2
 UniProt:Q5VZK9 CARMIL1  1 0.508 2
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