Reactome | GRIA1 [endocytic vesicle membrane]

GRIA1 [endocytic vesicle membrane]

Stable Identifier

R-HSA-3004479

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endocytic vesicle membrane

Synonyms

Glutamate receptor 1, GluR1, GRIA1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P42261 GRIA1

Gene Names

GRIA1, GLUH1, GLUR1

Chain

signal peptide:1-18, chain:19-906

Reference Genes

BioGPS Gene:2890 GRIA1

COSMIC (genes):GRIA1 GRIA1

CTD Gene:2890 GRIA1

dbSNP Gene:2890 GRIA1

ENSEMBL:ENSG00000155511 GRIA1

HGNC:4571 GRIA1

KEGG Gene (Homo sapiens):2890 GRIA1

Monarch:2890 GRIA1

NCBI Gene:2890 GRIA1

OMIM:138248 GRIA1

UCSC:P42261 GRIA1

Reference Transcript

Other Identifiers

0006200450

11739499_a_at

11745982_a_at

11745983_x_at

11748236_a_at

16991296

209793_at

211520_s_at

2836266

2836267

2836268

2836270

2836314

2836315

2836316

2836317

2836322

2836323

2836324

2836326

2836327

2836331

2836332

2836333

2836349

2836350

2836351

2836367

2836368

2836375

2836376

2836377

2836383

2836384

2836385

2836386

2836387

2836388

2890

36853_at

36854_s_at

36855_r_at

8109383

A_23_P303072

GE58235

GO:0001540

GO:0003674

GO:0004970

GO:0004971

GO:0005216

GO:0005515

GO:0005575

GO:0005576

GO:0005622

GO:0005737

GO:0005768

GO:0005783

GO:0005789

GO:0005886

GO:0006810

GO:0006811

GO:0006888

GO:0007165

GO:0007267

GO:0007268

GO:0007616

GO:0008021

GO:0008066

GO:0008150

GO:0008328

GO:0009986

GO:0012507

GO:0014069

GO:0015276

GO:0016020

GO:0016021

GO:0016192

GO:0022607

GO:0022857

GO:0030054

GO:0030165

GO:0030425

GO:0030666

GO:0030672

GO:0031410

GO:0031623

GO:0031901

GO:0032281

GO:0032590

GO:0032591

GO:0032991

GO:0033116

GO:0034220

GO:0035235

GO:0036477

GO:0038023

GO:0042592

GO:0042995

GO:0043005

GO:0043025

GO:0043197

GO:0043226

GO:0044297

GO:0044308

GO:0044309

GO:0045202

GO:0045211

GO:0048208

GO:0050877

GO:0055037

GO:0055038

GO:0055085

GO:0060076

GO:0060078

GO:0060292

GO:0061024

GO:0065003

GO:0071242

GO:0097060

GO:0098794

GO:0098839

GO:0098978

GO:0099061

GO:0099544

GO:0099566

GO:0099583

GO:1904315

GO:2000310

HMNXSV003051400

Hs.7117.1.A2_3p_at

ILMN_1750306

ILMN_2203299

M64752_at

M81886_s_at

PH_hs_0021980

TC05000849.hg

Z70220_at

g183280_3p_a_at

Participates

as a component of

Other forms of this molecule

GRIA1 [endoplasmic reticulum membrane]

GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

GRIA1 [ER to Golgi transport vesicle membrane]

p-S849-GRIA1 [plasma membrane]

GRIA1 [plasma membrane]

Inferred To

Ir76b [endocytic vesicle membrane] (Drosophila melanogaster)

GluRIIC [endocytic vesicle membrane] (Drosophila melanogaster)

glr-1 [endocytic vesicle membrane] (Caenorhabditis elegans)

Homologues of GRIA1 [endocytic vesicle membrane] (Caenorhabditis elegans)

Homologues of GRIA1 [endocytic vesicle membrane] (Drosophila melanogaster)

glr-5 [endocytic vesicle membrane] (Caenorhabditis elegans)

glr-6 [endocytic vesicle membrane] (Caenorhabditis elegans)

Ir75a [endocytic vesicle membrane] (Drosophila melanogaster)

Ir84a [endocytic vesicle membrane] (Drosophila melanogaster)

GRIA1 [endocytic vesicle membrane] (Canis familiaris)

GRIA1 [endocytic vesicle membrane] (Gallus gallus)

GRIA1 [endocytic vesicle membrane] (Sus scrofa)

Ir75d [endocytic vesicle membrane] (Drosophila melanogaster)

Gria1 [endocytic vesicle membrane] (Mus musculus)

Gria1 [endocytic vesicle membrane] (Rattus norvegicus)

glr-4 [endocytic vesicle membrane] (Caenorhabditis elegans)

GluRIA [endocytic vesicle membrane] (Drosophila melanogaster)

GluRIB [endocytic vesicle membrane] (Drosophila melanogaster)

KaiR1D [endocytic vesicle membrane] (Drosophila melanogaster)

Ir25a [endocytic vesicle membrane] (Drosophila melanogaster)

GluRIID [endocytic vesicle membrane] (Drosophila melanogaster)

gria1a [endocytic vesicle membrane] (Danio rerio)

glr-3 [endocytic vesicle membrane] (Caenorhabditis elegans)

GluRIIE [endocytic vesicle membrane] (Drosophila melanogaster)

Ir93a [endocytic vesicle membrane] (Drosophila melanogaster)

clumsy [endocytic vesicle membrane] (Drosophila melanogaster)

Ir8a [endocytic vesicle membrane] (Drosophila melanogaster)

Ir64a [endocytic vesicle membrane] (Drosophila melanogaster)

glr-2 [endocytic vesicle membrane] (Caenorhabditis elegans)

GluRIIB [endocytic vesicle membrane] (Drosophila melanogaster)

Ir21a [endocytic vesicle membrane] (Drosophila melanogaster)

GluRIIA [endocytic vesicle membrane] (Drosophila melanogaster)

Ir75c [endocytic vesicle membrane] (Drosophila melanogaster)

glr-7 [endocytic vesicle membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001244948.1, NP_001244952.1, NP_001244950.1, NP_001107655.1, NP_000818.2, NP_001244951.1

Guide to Pharmacology - Targets

444

OpenTargets

ENSG00000155511

ZINC target

P42261

PRO

P42261

GlyGen

P42261

PDB

6X5Q

HPA

ENSG00000155511-GRIA1

GeneCards

P42261

Ensembl

ENST00000448073, ENST00000340592, ENSP00000427864, ENSP00000339343, ENST00000518142, ENSP00000285900, ENSG00000155511, ENST00000521843, ENST00000285900, ENSP00000415569, ENSP00000427920, ENST00000518783, ENSP00000428994

Pharos - Targets

P42261

Orphanet

28185

HMDB Protein

HMDBP02795

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6XD76 ASCL4			0.556	3
UniProt:Q15907 RAB11B	3	GGC-RAB11B [cytosol] (R-HSA-8873766) RAB11B [cytosol] (R-HSA-8873671) RAB11B [recycling endosome membrane] (R-HSA-8854762)	0.556	3
UniProt:Q9UNY5 ZN232			0.556	3
UniProt:Q14457 BECN1	3	K63polyUb-BECN1 [cytosol] (R-HSA-6782989) p-S15-BECN1 [cytosol] (R-HSA-5682391) BECN1 [cytosol] (R-HSA-1632841)	0.556	3
UniProt:Q9UIH9 KLF15	1	KLF15 [nucleoplasm] (R-HSA-8878735)	0.556	3

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