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p-S849-GRIA1 [plasma membrane]
Stable Identifier
R-HSA-9620488
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
p-S849-GluR1
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Post NMDA receptor activation events (Homo sapiens)
Long-term potentiation (Homo sapiens)
CaMKII phosphorylates AMPA receptor (Homo sapiens)
Ca impermeable p-S849-GRIA1:GRIA2 AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
p-S849-GRIA1:GRIA2 AMPA receptor [plasma membrane] (Homo sapiens)
p-S849-GRIA1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P42261 GRIA1
Gene Names
GRIA1, GLUH1, GLUR1
Chain
signal peptide:1-18, chain:19-906
Reference Genes
BioGPS Gene:2890 GRIA1
COSMIC (genes):GRIA1 GRIA1
CTD Gene:2890 GRIA1
dbSNP Gene:2890 GRIA1
ENSEMBL:ENSG00000155511 GRIA1
HGNC:4571 GRIA1
KEGG Gene (Homo sapiens):2890 GRIA1
Monarch:2890 GRIA1
NCBI Gene:2890 GRIA1
OMIM:138248 GRIA1
UCSC:P42261 GRIA1
Reference Transcript
RefSeq:NM_000827.3 GRIA1
RefSeq:NM_001258023.1 GRIA1
RefSeq:NM_001258019.1 GRIA1
RefSeq:NM_001114183.1 GRIA1
RefSeq:NM_001258022.1 GRIA1
RefSeq:NM_001258021.1 GRIA1
Other Identifiers
0006200450
11739499_a_at
11745982_a_at
11745983_x_at
11748236_a_at
16991296
209793_PM_at
209793_at
211520_PM_s_at
211520_s_at
2836266
2836267
2836268
2836270
2836314
2836315
2836316
2836317
2836322
2836323
2836324
2836326
2836327
2836331
2836332
2836333
2836349
2836350
2836351
2836367
2836368
2836375
2836376
2836377
2836383
2836384
2836385
2836386
2836387
2836388
2890
36853_at
36854_s_at
36855_r_at
8109383
A_23_P303072
GE58235
GO:0001540
GO:0003674
GO:0004970
GO:0004971
GO:0005216
GO:0005515
GO:0005575
GO:0005576
GO:0005622
GO:0005737
GO:0005768
GO:0005783
GO:0005789
GO:0005886
GO:0006810
GO:0006811
GO:0007165
GO:0007267
GO:0007268
GO:0007616
GO:0008021
GO:0008066
GO:0008150
GO:0008328
GO:0009986
GO:0012507
GO:0014069
GO:0015276
GO:0016020
GO:0016021
GO:0016192
GO:0022857
GO:0030054
GO:0030165
GO:0030425
GO:0030666
GO:0030672
GO:0031410
GO:0031623
GO:0031901
GO:0032281
GO:0032590
GO:0032591
GO:0032991
GO:0033116
GO:0034220
GO:0035235
GO:0036477
GO:0038023
GO:0042592
GO:0042995
GO:0043005
GO:0043025
GO:0043197
GO:0043226
GO:0044297
GO:0044308
GO:0044309
GO:0045202
GO:0045211
GO:0050877
GO:0055037
GO:0055038
GO:0055085
GO:0060076
GO:0060078
GO:0060292
GO:0071242
GO:0097060
GO:0098793
GO:0098794
GO:0098839
GO:0098978
GO:0099061
GO:0099544
GO:0099566
GO:0099583
GO:1904315
HMNXSV003051400
Hs.7117.1.A2_3p_at
ILMN_1750306
ILMN_2203299
M64752_at
M81886_s_at
PH_hs_0021980
TC05000849.hg
Z70220_at
g183280_3p_a_at
Participates
as a component of
p-S849-GRIA1:GRIA2 AMPA receptor [plasma membrane] (Homo sapiens)
Other forms of this molecule
GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GRIA1 [ER to Golgi transport vesicle membrane]
GRIA1 [endoplasmic reticulum membrane]
GRIA1 [endocytic vesicle membrane]
GRIA1 [plasma membrane]
Modified Residues
Name
N4-glycosyl-L-asparagine at unknown position
PsiMod Name
N4-glycosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to an N4-glycosyl-L-asparagine.
Name
O-phospho-L-serine at 849
Coordinate
849
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001244948.1
,
NP_001244952.1
,
NP_001107655.1
,
NP_000818.2
,
NP_001244950.1
,
NP_001244951.1
Guide to Pharmacology - Targets
444
OpenTargets
ENSG00000155511
GeneCards
P42261
HPA
ENSG00000155511-GRIA1
ZINC target
P42261
Ensembl
ENST00000518783
,
ENSP00000427864
,
ENSP00000428994
,
ENSG00000155511
,
ENSP00000285900
,
ENSP00000339343
,
ENST00000285900
,
ENSP00000415569
,
ENSP00000427920
,
ENST00000518142
,
ENST00000448073
,
ENST00000521843
,
ENST00000340592
PRO
P42261
Pharos - Targets
P42261
Orphanet
28185
HMDB Protein
HMDBP02795
PDB
6X5Q
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6XD76 ASCL4
0.556
3
UniProt:Q15907 RAB11B
3
RAB11B [recycling endosome membrane]
(R-HSA-8854762)
GGC-RAB11B [cytosol]
(R-HSA-8873766)
RAB11B [cytosol]
(R-HSA-8873671)
0.556
3
UniProt:Q9UNY5 ZN232
0.556
3
UniProt:Q14457 BECN1
3
K63polyUb-BECN1 [cytosol]
(R-HSA-6782989)
p-S15-BECN1 [cytosol]
(R-HSA-5682391)
BECN1 [cytosol]
(R-HSA-1632841)
0.556
3
UniProt:Q9UIH9 KLF15
1
KLF15 [nucleoplasm]
(R-HSA-8878735)
0.556
3
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