Reactome | MRM1 [mitochondrial matrix]

MRM1 [mitochondrial matrix]

Stable Identifier

R-HSA-6793088

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

fullName evidence="7"rRNA methyltransferase 1, mitochondrial ecNumber evidence="11"2.1.1.-/ecNumber, MRM1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6IN84 MRM1

Gene Names

MRM1

Chain

transit peptide:1-20, chain:21-353

Reference Genes

BioGPS Gene:79922 MRM1

CTD Gene:79922 MRM1

dbSNP Gene:79922 MRM1

ENSEMBL:ENSG00000278619 MRM1

ENSEMBL_homo_sapiens_GENE:ENSG00000274853.2 MRM1

ENSEMBL_homo_sapiens_GENE:ENSG00000278619.5 MRM1

HGNC:26202 MRM1

KEGG Gene (Homo sapiens):79922 MRM1

Monarch:79922 MRM1

NCBI Gene:79922 MRM1

UCSC:Q6IN84 MRM1

Reference Transcript

RefSeq:NM_024864.4 MRM1

Other Identifiers

11725721_a_at

16833488

219967_PM_at

219967_at

3719232

3719233

3719234

3719235

3719236

3719237

3719238

3719239

3719240

3719241

3719242

79922

8006668

A_23_P15603

GE82970

GE85454

GO:0000154

GO:0000451

GO:0003723

GO:0003824

GO:0005515

GO:0005737

GO:0005739

GO:0005759

GO:0006364

GO:0006396

GO:0008168

GO:0008173

GO:0016435

GO:0016740

GO:0031167

GO:0032259

GO:0042254

GO:0043226

GO:0070039

GO:0140098

HMNXSV003013345

HMNXSV003031616

ILMN_1793643

PH_hs_0011531

TC17000440.hg

g13376295_3p_at

Cross References

RefSeq

NP_079140.2

OpenTargets

ENSG00000278619

GeneCards

Q6IN84

HPA

ENSG00000278619-MRM1

Ensembl

ENST00000611231, ENST00000614766, ENSP00000478520, ENSG00000278619, ENSP00000481559, ENSG00000274853

PRO

Q6IN84

Pharos - Targets

Q6IN84

Interactors (58)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UFW8 CGBP1			0.742	7
UniProt:Q6RW13 AGTRAP	2	AGTRAP(1-159)-p-BRAF(288-545) fusion [cytosol] (R-HSA-6802511) AGTRAP(1-159)-BRAF(288-545) fusion [cytosol] (R-HSA-6802262)	0.556	3
UniProt:Q96LL9 DJC30			0.556	3
UniProt:Q92482 AQP3	1	AQP3 [plasma membrane] (R-HSA-431723)	0.556	3
UniProt:Q9UBY5 LPAR3	1	LPAR3 [plasma membrane] (R-HSA-419379)	0.556	3
UniProt:Q5GAN6 RNS10			0.556	3
UniProt:Q9Y680 FKBP7			0.556	3
UniProt:A5PKU2 A5PKU2			0.556	3
UniProt:Q9UKR5 ERG28			0.556	3
UniProt:Q96DZ9-2 CMTM5			0.556	3
UniProt:Q6PL45-2 BRICD5			0.556	3
UniProt:P02808 STAT			0.556	3
UniProt:Q9BT56 SPXN			0.556	3
UniProt:Q6UX27-3 VSTM1			0.556	3
UniProt:Q6NTF9-3 Q6NTF93			0.556	3
UniProt:O14880 MGST3	1	MGST3 [endoplasmic reticulum membrane] (R-HSA-176053)	0.556	3
UniProt:Q69YG0 TMM42			0.556	3
UniProt:Q9BQG1 SYT3			0.556	3
UniProt:Q96MX0 CKLF3			0.556	3
UniProt:Q969L2 MAL2			0.556	3
UniProt:P13236 CCL4	1	CCL4(24-92) [extracellular region] (R-HSA-443976)	0.556	3
UniProt:Q8IXM6 NRM			0.556	3
UniProt:Q8NHW4 CCL4L1	1	CCL4L1 [extracellular region] (R-HSA-8865389)	0.556	3
UniProt:Q969Y0 NXPE3			0.556	3
UniProt:P49638 TTPA	1	TTPA [cytosol] (R-HSA-2980979)	0.556	3
UniProt:P17152 TMEM11	1	TMEM11 [mitochondrial inner membrane] (R-HSA-8949578)	0.556	3
UniProt:Q15848 ADIPOQ	1	ADIPOQ [extracellular region] (R-HSA-1183052)	0.556	3
UniProt:Q96E93 KLRG1	1	KLRG1 [plasma membrane] (R-HSA-198006)	0.556	3
UniProt:O95406 CNIH1	3	CNIH1 [endoplasmic reticulum membrane] (R-HSA-5689439) CNIH1 [ER to Golgi transport vesicle membrane] (R-HSA-5689776) CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5689778)	0.556	3
UniProt:P08247 SYP	1	SYP [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-5215991)	0.556	3
UniProt:Q14696 MESD			0.556	3
UniProt:Q8NI60 COQ8A	1	COQ8A [mitochondrial inner membrane] (R-HSA-9856284)	0.556	3
UniProt:P62508-3 ESRRG			0.556	5
UniProt:Q9Y6D0 SELK			0.556	3
UniProt:Q8N0U8 VKORC1L1	1	VKORC1L1 [endoplasmic reticulum membrane] (R-HSA-2980944)	0.556	3
UniProt:Q5BJF2 SGMR2			0.556	3
UniProt:Q6RW13-2 AGTRAP			0.556	3
UniProt:P29972 AQP1	1	AQP1 [plasma membrane] (R-HSA-431700)	0.556	3
UniProt:O15400 STX7			0.556	3
UniProt:Q9BU79 TM243			0.556	3
UniProt:P41181 AQP2	3	AQP2 [transport vesicle membrane] (R-HSA-432215) p-S256-AQP2 [transport vesicle membrane] (R-HSA-432222) p-S256-AQP2 [plasma membrane] (R-HSA-432231)	0.556	3
UniProt:P11215 ITGAM	3	ITGAM [specific granule membrane] (R-HSA-6799647) ITGAM [tertiary granule membrane] (R-HSA-6800979) ITGAM [plasma membrane] (R-HSA-202757)	0.556	3
UniProt:Q9Y2Z4 YARS2	1	YARS2 [mitochondrial matrix] (R-HSA-379634)	0.527	2
UniProt:O95260 ATE1			0.527	4
UniProt:Q8TAA5 GRPEL2	1	GRPEL2 [mitochondrial inner membrane] (R-HSA-1252076)	0.527	3
UniProt:Q99797 MIPEP			0.527	2
UniProt:P52815 MRPL12	2	MRPL12 [mitochondrial matrix] (R-HSA-9839674) MRPL12 [mitochondrial inner membrane] (R-HSA-5368256)	0.527	2
UniProt:Q7Z7L7 ZER1			0.527	4
UniProt:Q9BVL4 SELO			0.527	4
UniProt:Q8IWV7 UBR1	1	UBR1 [cytosol] (R-HSA-976040)	0.527	4
UniProt:Q96QK1 VPS35	1	VPS35 [cytosol] (R-HSA-3247740)	0.527	4
UniProt:O43149 ZZEF1			0.527	4
UniProt:Q4G0F5 VP26B			0.527	4
UniProt:Q8N5M1 ATPF2			0.527	2
UniProt:Q5T447 HECTD3	1	HECTD3 [cytosol] (R-HSA-975991)	0.527	4
UniProt:Q9C0D3 ZY11B			0.527	4
UniProt:P11182 DBT	11	DBT [cytosol] (R-HSA-9714663) I98M Lipo-K105-DBT [mitochondrial matrix] (R-HSA-9865057) Lipo-K105-DBT [mitochondrial matrix] (R-HSA-70017) Isobutyryl-lipoH2-K105-DBT [mitochondrial matrix] (R-HSA-9859151) Isovaleryl-lipoH2-K105-DBT [mitochondrial matrix] (R-HSA-9859144) 2-Methylbutyryl-lipoH2-K105-DBT [mitochondrial matrix] (R-HSA-9859145) LipoH2-K105-DBT [mitochondrial matrix] (R-HSA-9859167) DBT [mitochondrial matrix] (R-HSA-6792584) P276C Lipo-K105-DBT [mitochondrial matrix] (R-HSA-9865046) S399C Lipo-K105-DBT [mitochondrial matrix] (R-HSA-9865036) K313_Y338del Lipo-K105-DBT [mitochondrial matrix] (R-HSA-9865051)	0.527	3
UniProt:P46199 MTIF2	1	MTIF2 [mitochondrial matrix] (R-HSA-5368271)	0.527	3

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