Reactome | VKORC1L1 [endoplasmic reticulum membrane]

VKORC1L1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-2980944

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Vitamin K epoxide reductase complex subunit 1-like protein 1, VKORL_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8N0U8 VKORC1L1

Gene Names

VKORC1L1

Chain

chain:1-176

Reference Genes

BioGPS Gene:154807 VKORC1L1

COSMIC (genes):VKORC1L1 VKORC1L1

CTD Gene:154807 VKORC1L1

dbSNP Gene:154807 VKORC1L1

ENSEMBL:ENSG00000196715 VKORC1L1

ENSEMBL:ENSG00000196715.7 VKORC1L1

HGNC:21492 VKORC1L1

KEGG Gene (Homo sapiens):154807 VKORC1L1

Monarch:154807 VKORC1L1

NCBI Gene:154807 VKORC1L1

OMIM:608838 VKORC1L1

UCSC:Q8N0U8 VKORC1L1

Reference Transcript

Other Identifiers

11730865_a_at

11759041_x_at

11759042_at

11759043_at

11759044_a_at

154807

1553679_PM_s_at

1553679_s_at

17046595

224881_PM_at

224881_at

3005267

3005268

3005269

3005271

3005272

3005273

3005274

3005275

3005276

3005277

3005278

3005279

3005313

3005315

43985_at

45218_at

75257_at

8133114

85205_at

85616_r_at

86501_at

A_14_P115643

A_23_P413815

GE56747

GE803188

GO:0003824

GO:0005515

GO:0005783

GO:0005789

GO:0006766

GO:0016020

GO:0016491

GO:0016728

GO:0017187

GO:0034599

GO:0036211

GO:0042373

GO:0043226

GO:0047057

GO:0048038

HMNXSV003012499

HMNXSV003047357

Hs.43112.0.S1_3p_at

Hs2.422727.1.S1_3p_s_at

ILMN_1802894

PH_hs_0003149

TC07000403.hg

p26431

Inferred To

zgc:112358 [endoplasmic reticulum membrane] (Danio rerio)

VKORC1L1 [endoplasmic reticulum membrane] (Bos taurus)

VKORC1L1 [endoplasmic reticulum membrane] (Canis familiaris)

VKORC1L1 [endoplasmic reticulum membrane] (Gallus gallus)

VKORC1L1 [endoplasmic reticulum membrane] (Mus musculus)

VKORC1L1 [endoplasmic reticulum membrane] (Rattus norvegicus)

VKORC1L1 [endoplasmic reticulum membrane] (Sus scrofa)

vkorc1l1 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_001271271.1, NP_775788.2

OpenTargets

ENSG00000196715

GeneCards

Q8N0U8

HPA

ENSG00000196715-VKORC1L1

Ensembl

ENSP00000403077, ENST00000648179, ENSP00000497394, ENST00000434382, ENSG00000196715, ENSP00000353998, ENST00000360768

PRO

Q8N0U8

Pharos - Targets

Q8N0U8

HMDB Protein

HMDBP10633

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6IN84 MRM1	1	MRM1 [mitochondrial matrix] (R-HSA-6793088)	0.556	3
UniProt:Q8N5K1 CISD2			0.556	3
UniProt:Q96HE8 TMM80			0.556	3
UniProt:P01019 AGT	9	AGT(36-41) [cytosol] (R-HSA-8852193) AGT(35-41) [cytosol] (R-HSA-8852195) AGT(36-41) [extracellular region] (R-HSA-2022355) AGT(35-41) [extracellular region] (R-HSA-2022354) AGT(34-40) [extracellular region] (R-HSA-2022351) AGT(34-42) [extracellular region] (R-HSA-2022348) AGT [extracellular region] (R-HSA-1998759) AGT(34-43) [extracellular region] (R-HSA-2022346) AGT(34-41) [extracellular region] (R-HSA-374187)	0.556	3
UniProt:Q13520 AQP6	1	AQP6 [transport vesicle membrane] (R-HSA-431741)	0.556	3
UniProt:P49585 PCYT1A	1	PCYT1A [endoplasmic reticulum membrane] (R-HSA-1498771)	0.556	3
UniProt:P06858 LPL	1	LPL [extracellular region] (R-HSA-174605)	0.556	3
UniProt:P03952 KLKB1	5	KLKB1(20-390) [extracellular region] (R-HSA-158239) KLKB1(391-638) [extracellular region] (R-HSA-158181) KLKB1(20-638) [plasma membrane] (R-HSA-158385) KLKB1(20-390) [plasma membrane] (R-HSA-158213) KLKB1(391-638) [plasma membrane] (R-HSA-158277)	0.556	3
UniProt:Q5T7V8 GORAB			0.556	3
UniProt:Q9H2K0 MTIF3	1	MTIF3 [mitochondrial matrix] (R-HSA-5368284)	0.556	3
UniProt:P40337-2 VHL			0.556	3
UniProt:Q8WUW1 BRK1	1	BRK1 [cytosol] (R-HSA-1671645)	0.556	3
UniProt:Q9Y5K3-3 PCYT1B			0.556	8
UniProt:Q96HJ5 MS4A3	2	MS4A3 [plasma membrane] (R-HSA-6806321) MS4A3 [specific granule membrane] (R-HSA-6799514)	0.556	3
UniProt:Q8TED1 GPX8	1	GPX8 [endoplasmic reticulum lumen] (R-HSA-3341303)	0.556	3
UniProt:P78371 CCT2	3	CCT2 [extracellular region] (R-HSA-6806220) CCT2 [cytosol] (R-HSA-390464) CCT2 [azurophil granule lumen] (R-HSA-6799356)	0.556	3
UniProt:Q9Y282 ERGI3			0.556	3

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