Reactome | COQ8A [mitochondrial inner membrane]

COQ8A [mitochondrial inner membrane]

Stable Identifier

R-HSA-9856284

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

ADCK3

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8NI60 COQ8A

Gene Names

COQ8A, ADCK3, CABC1, PP265

Chain

transit peptide:1-162, chain:163-647

Reference Genes

BioGPS Gene:56997 COQ8A

COSMIC (genes):COQ8A COQ8A

CTD Gene:56997 COQ8A

dbSNP Gene:56997 COQ8A

ENSEMBL:ENSG00000163050 COQ8A

ENSEMBL_homo_sapiens_GENE:ENSG00000163050.18 COQ8A

HGNC:16812 COQ8A

KEGG Gene (Homo sapiens):56997 COQ8A

Monarch:56997 COQ8A

NCBI Gene:56997 COQ8A

OMIM:606980 COQ8A

UCSC:Q8NI60 COQ8A

Reference Transcript

Other Identifiers

11732135_a_at

11747618_a_at

11747732_a_at

16678191

218168_PM_s_at

218168_s_at

222542_PM_x_at

222542_x_at

2383379

2383389

2383390

2383391

2383392

2383393

2383394

2383395

2383396

2383404

2383407

2383409

2383411

2383413

2383416

2383419

2383420

2383421

2383422

2383424

2383425

45334_at

56997

7910164

A_14_P124660

A_23_P85598

GE88281

GO:0000166

GO:0003824

GO:0005515

GO:0005524

GO:0005739

GO:0006744

GO:0016020

GO:0016301

GO:0016310

GO:0016740

GO:0043226

GO:0043531

HMNXSV003053299

Hs.273186.0.S1_3p_a_at

ILMN_1731064

PH_hs_0014100

g9910387_3p_a_at

Participates

as a member of

COQ8A,B [mitochondrial inner membrane] (Homo sapiens)

Inferred To

Q29RI0 [mitochondrial inner membrane] (Bos taurus)

P27697 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

Q54IH6 [mitochondrial inner membrane] (Dictyostelium discoideum)

Q60936 [mitochondrial inner membrane] (Mus musculus)

Coq8 [mitochondrial inner membrane] (Drosophila melanogaster)

Q18486 [mitochondrial inner membrane] (Caenorhabditis elegans)

COQ8A [mitochondrial inner membrane] (Canis familiaris)

COQ8A [mitochondrial inner membrane] (Gallus gallus)

COQ8A [mitochondrial inner membrane] (Sus scrofa)

coq8a [mitochondrial inner membrane] (Xenopus tropicalis)

Q5RGU1 [mitochondrial inner membrane] (Danio rerio)

Q5BJQ0 [mitochondrial inner membrane] (Rattus norvegicus)

abc1 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

Cross References

RefSeq

XP_011542540.1, XP_011542542.1, XP_005273258.1, NP_064632.2, XP_016857341.1, XP_011542541.1, XP_011542543.1

Guide to Pharmacology - Targets

1927

OpenTargets

ENSG00000163050

GeneCards

Q8NI60

HPA

ENSG00000163050-COQ8A

ZINC target

Q8NI60

Ensembl

ENST00000366778, ENSG00000163050, ENSP00000355739, ENSP00000355740, ENST00000366777

PRO

Q8NI60

Pharos - Targets

Q8NI60

Orphanet

16939

PDB

7UDQ, 5I35, 7UDP, 4PED

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.849	13
UniProt:Q8WTS1 ABHD5	2	ABHD5 [lipid droplet] (R-HSA-163485) ABHD5 [cytosol] (R-HSA-163531)	0.556	3
UniProt:Q6IN84 MRM1	1	MRM1 [mitochondrial matrix] (R-HSA-6793088)	0.556	3
UniProt:Q9H2K0 MTIF3	1	MTIF3 [mitochondrial matrix] (R-HSA-5368284)	0.556	3
UniProt:O60906 SMPD2	1	SMPD2 [plasma membrane] (R-HSA-194337)	0.556	3
UniProt:Q9H0Y0 ATG10	2	GlyK166-ATG10 [cytosol] (R-HSA-5683572) ATG10 [cytosol] (R-HSA-5671733)	0.556	3
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3

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