Reactome | YARS2 [mitochondrial matrix]

YARS2 [mitochondrial matrix]

Stable Identifier

R-HSA-379634

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Tyrosyl-tRNA synthetase 2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y2Z4 YARS2

Gene Names

YARS2, CGI-04

Chain

transit peptide:1-16, chain:17-477

Reference Genes

BioGPS Gene:51067 YARS2

COSMIC (genes):YARS2 YARS2

CTD Gene:51067 YARS2

dbSNP Gene:51067 YARS2

ENSEMBL:ENSG00000139131 YARS2

HGNC:24249 YARS2

KEGG:hsa:51067 YARS2

Monarch:51067 YARS2

NCBI Gene:51067 YARS2

OMIM:610957 YARS2

UCSC:Q9Y2Z4 YARS2

Reference Transcript

RefSeq:NM_001040436.2 YARS2

Other Identifiers

11720937_a_at

16763021

218470_PM_at

218470_at

3354962

3354968

34099_f_at

3450183

3450184

3450185

3450186

3450187

3450188

3450189

3450190

3450191

3450192

3450193

3450194

3450195

3450202

3450203

3450204

3450205

3450206

3450207

3450210

3450211

3450212

3450213

3450214

3450215

3450216

3462854

3462855

3462858

3462877

44985_at

45688_at

51067

71128_r_at

7962203

A_23_P151093

GE58619

GO:0000049

GO:0000166

GO:0003723

GO:0003824

GO:0004812

GO:0004831

GO:0005515

GO:0005524

GO:0005739

GO:0005759

GO:0005829

GO:0006399

GO:0006412

GO:0006418

GO:0006437

GO:0006520

GO:0016604

GO:0016874

GO:0042803

GO:0043039

GO:0043226

GO:0070184

GO:0072545

GO:0140098

HMNXSV003016589

ILMN_1782635

PH_hs_0024268

TC12001376.hg

Participates

as a component of

YARS2 dimer [mitochondrial matrix] (Homo sapiens)

Cross References

ENSEMBL

ENST00000324868, ENSG00000139131, ENSP00000320658

OpenTargets

ENSG00000139131

GeneCards

YARS2

HPA

ENSG00000139131-YARS2

PRO

Q9Y2Z4

Pharos - Targets

Q9Y2Z4

GlyGen

Q9Y2Z4

Orphanet

YARS2

HMDB Protein

HMDBP00619

PDB

3ZXI, 2PID

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12834 CDC20	3	CDC20 [cytosol] (R-HSA-141412) CDC20 [nucleoplasm] (R-HSA-174112) PolyUb-CDC20 [nucleoplasm] (R-HSA-6783069)	0.669	4
UniProt:P10809 HSPD1	6	HSPD1(1-26) [mitochondrial matrix] (R-HSA-8986171) HSPD1(1-573) [mitochondrial inner membrane] (R-HSA-1299442) HSPD1 [mitochondrial inner membrane] (R-HSA-1299455) HSPD1(1-573) [mitochondrial intermembrane space] (R-HSA-1267963) HSPD1(1-573) [cytosol] (R-HSA-1267989) HSPD1 [mitochondrial matrix] (R-HSA-1299448)	0.615	3
UniProt:Q6IN84 MRM1	1	MRM1 [mitochondrial matrix] (R-HSA-6793088)	0.527	2
UniProt:Q9NU23 LYRM2	1	LYRM2 [mitochondrial matrix] (R-HSA-9906752)	0.527	2
UniProt:Q00839 HNRNPU	1	HNRNPU [nucleoplasm] (R-HSA-71953)	0.527	2
UniProt:Q9UBU9 NXF1	2	NXF1 [nucleoplasm] (R-HSA-111690) NXF1 [cytosol] (R-HSA-156481)	0.527	2
UniProt:Q8IXZ2 ZC3H3	1	ZC3H3 [nucleoplasm] (R-HSA-9933572)	0.527	3

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