Reactome | DBT [mitochondrial matrix]

DBT [mitochondrial matrix]

Stable Identifier

R-HSA-6792584

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

dihydrolipoamide branched chain transacylase E2, DBT

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
7918575	Differential processing of human and rat E1 alpha precursors of the branched-chain alpha-keto acid dehydrogenase complex caused by an N-terminal proline in the rat sequence Wynn, RM, Kochi, H, Cox, RP, Chuang, DT	Biochim Biophys Acta	1994
11839747	Solution structure and dynamics of the lipoic acid-bearing domain of human mitochondrial branched-chain alpha-keto acid dehydrogenase complex Chang, CF, Chou, HT, Chuang, JL, Chuang, DT, Huang, TH	J Biol Chem	2002

External Reference Information

External Reference

UniProt:P11182 DBT

Gene Names

DBT, BCATE2

Chain

transit peptide:1-61, chain:62-482

Reference Genes

BioGPS Gene:1629 DBT

COSMIC (genes):DBT DBT

CTD Gene:1629 DBT

dbSNP Gene:1629 DBT

ENSEMBL:ENSG00000137992 DBT

HGNC:2698 DBT

KEGG Gene (Homo sapiens):1629 DBT

Monarch:1629 DBT

NCBI Gene:1629 DBT

OMIM:248610 DBT

UCSC:P11182 DBT

Reference Transcript

RefSeq:NM_001918.3 DBT

Other Identifiers

0001400441

0106290563

11731509_x_at

11731510_at

11731511_s_at

11751182_a_at

11752357_a_at

1629

16690103

205369_3p_x_at

205369_x_at

205370_x_at

205371_s_at

231919_at

2425203

2425205

2425207

2425209

2425210

2425211

2425213

2425214

2425215

2425216

2425217

2425218

2425219

2425221

2425231

2425233

2425234

2425237

2425238

2425239

2425240

2425242

244687_at

51919_at

7918008

86425_at

A_23_P74022

A_24_P28524

A_32_P50005

A_33_P3308949

GE59930

GE85471

GO:0003674

GO:0005575

GO:0005622

GO:0005737

GO:0005739

GO:0005759

GO:0005947

GO:0006520

GO:0008150

GO:0008289

GO:0009056

GO:0009083

GO:0016407

GO:0016740

GO:0016746

GO:0019899

GO:0031405

GO:0031625

GO:0032991

GO:0042645

GO:0043167

GO:0043226

GO:0043754

GO:0044281

Hs.199210.0.A1_3p_at

Hs.257043.0.S1_3p_at

ILMN_1714990

ILMN_1887403

M27093_s_at

PH_hs_0013509

PH_hs_0021360

PH_hs_0027858

TC01002918.hg

X66785_at

g179353_3p_a_at

g179353_3p_x_at

g186635_3p_a_at

g4503264_3p_at

g736674_3p_a_at

Participant Of

hasComponent

BCKDH [mitochondrial matrix]

Other forms of this molecule

lipo-K44-DBT [mitochondrial matrix]

Inferred To

Dbt [mitochondrial matrix] (Mus musculus)

Dbt [mitochondrial matrix] (Rattus norvegicus)

dbt [mitochondrial matrix] (Danio rerio)

Dmel\CG5599 [mitochondrial matrix] (Drosophila melanogaster)

bkdC [mitochondrial matrix] (Dictyostelium discoideum)

dbt-1 [mitochondrial matrix] (Caenorhabditis elegans)

DBT [mitochondrial matrix] (Canis familiaris)

DBT [mitochondrial matrix] (Gallus gallus)

DBT [mitochondrial matrix] (Plasmodium falciparum)

DBT [mitochondrial matrix] (Sus scrofa)

DBT [mitochondrial matrix] (Xenopus tropicalis)

Cross References

RefSeq

NP_001909.3

OpenTargets

ENSG00000137992

HPA

ENSG00000137992-DBT

GeneCards

P11182

Ensembl

ENSP00000359151, ENSG00000137992, ENST00000370132

PRO

P11182

Orphanet

15851

PDB

1K8M, 3RNM, 2COO, 1K8O, 1ZWV

HMDB Protein

HMDBP03078