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UBR2 [cytosol]
Stable Identifier
R-HSA-976055
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase UBR2, UBR2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBR2 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBR2 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBR2 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBR2 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBR2 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBR2 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBR2 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBR2 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBR2 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBR2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IWV8 UBR2
Gene Names
UBR2, C6orf133, KIAA0349
Chain
initiator methionine:, chain:2-1755
Reference Genes
COSMIC (genes):UBR2 Q8IWV82
dbSNP Gene:23304 Q8IWV82
ENSEMBL:ENSG00000024048 UBR2
Participates
as a member of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
ubr-1 [cytosol]
(Caenorhabditis elegans)
ubr1 [cytosol]
(Schizosaccharomyces pombe)
Ubr2 [cytosol]
(Rattus norvegicus)
UBR2 [cytosol]
(Bos taurus)
UBR2 [cytosol]
(Canis familiaris)
UBR2 [cytosol]
(Gallus gallus)
UBR2 [cytosol]
(Mus musculus)
UBR2 [cytosol]
(Saccharomyces cerevisiae)
UBR2 [cytosol]
(Sus scrofa)
Ubr1 [cytosol]
(Drosophila melanogaster)
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