Reactome | AQP3 [plasma membrane]

AQP3 [plasma membrane]

Stable Identifier

R-HSA-431723

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Aquaporin-3, AQP3_HUMAN

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External Reference Information

External Reference

UniProt:Q92482 AQP3

Gene Names

AQP3

Chain

chain:1-292

Reference Genes

BioGPS Gene:360 AQP3

COSMIC (genes):AQP3 AQP3

CTD Gene:360 AQP3

dbSNP Gene:360 AQP3

ENSEMBL:ENSG00000165272 AQP3

ENSEMBL_homo_sapiens_GENE:ENSG00000165272.16 AQP3

HGNC:636 AQP3

KEGG Gene (Homo sapiens):360 AQP3

Monarch:360 AQP3

NCBI Gene:360 AQP3

OMIM:600170 AQP3

UCSC:Q92482 AQP3

Reference Transcript

Other Identifiers

11747494_a_at

11756585_a_at

17093245

203747_PM_at

203747_at

3203570

3203571

3203572

3203573

3203574

3203576

3203577

3203580

3203581

360

39248_PM_at

39248_at

39249_3p_at

39249_PM_at

39249_at

47982_at

4855867C_3p_at

8160670

AB001325_at

A_23_P112481

A_23_P112482

A_33_P3209591

GE61894

GO:0002376

GO:0002684

GO:0002931

GO:0003014

GO:0003091

GO:0005215

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005886

GO:0005911

GO:0006833

GO:0015204

GO:0015250

GO:0015254

GO:0015267

GO:0015791

GO:0015793

GO:0015840

GO:0016020

GO:0016323

GO:0030154

GO:0032526

GO:0033280

GO:0042476

GO:0042802

GO:0043226

GO:0045616

GO:0048856

GO:0051592

GO:0051649

GO:0055085

GO:0070295

GO:0071456

GO:0071918

HMNXSV003030661

ILMN_1651574

PH_hs_0012796

TC09001012.hg

Participates

as a protein marker of

as a component of

AQP3 tetramer [plasma membrane] (Homo sapiens)

Inferred To

Homologues of AQP3 [plasma membrane] (Caenorhabditis elegans)

Homologues of AQP3 [plasma membrane] (Saccharomyces cerevisiae)

aqp3 [plasma membrane] (Xenopus tropicalis)

aqp-8 [plasma membrane] (Caenorhabditis elegans)

AQP3 [plasma membrane] (Bos taurus)

AQP3 [plasma membrane] (Canis familiaris)

AQP3 [plasma membrane] (Gallus gallus)

AQP3 [plasma membrane] (Plasmodium falciparum)

AQP3 [plasma membrane] (Schizosaccharomyces pombe)

AQP3 [plasma membrane] (Sus scrofa)

aqp-1 [plasma membrane] (Caenorhabditis elegans)

aqp-2 [plasma membrane] (Caenorhabditis elegans)

aqp-7 [plasma membrane] (Caenorhabditis elegans)

aqp-3 [plasma membrane] (Caenorhabditis elegans)

aqp3a [plasma membrane] (Danio rerio)

Aqp3 [plasma membrane] (Mus musculus)

Aqp3 [plasma membrane] (Rattus norvegicus)

FPS1 [plasma membrane] (Saccharomyces cerevisiae)

AQY3 [plasma membrane] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_001305073.1, NP_004916.1

Guide to Pharmacology - Targets

690

OpenTargets

ENSG00000165272

GeneCards

Q92482

HPA

ENSG00000165272-AQP3

Ensembl

ENST00000297991, ENSG00000165272, ENSP00000297991

PRO

Q92482

Pharos - Targets

Q92482

HMDB Protein

HMDBP02583

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01375 TNF	5	TNF(52-76) [extracellular region] (R-HSA-8863375) TNF(1-34) [plasma membrane] (R-HSA-8863367) TNF(1-76) [plasma membrane] (R-HSA-8863120) TNF(77-233) [extracellular region] (R-HSA-976821) TNF(1-233) [plasma membrane] (R-HSA-66220)	0.556	3
UniProt:Q6IN84 MRM1	1	MRM1 [mitochondrial matrix] (R-HSA-6793088)	0.556	3
UniProt:Q16623 STX1A	5	STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.556	3
UniProt:O95470 SGPL1	1	PXLP-SGPL1 [endoplasmic reticulum membrane] (R-HSA-428661)	0.556	3
UniProt:A8MZ59 LEUTX	1	LEUTX [nucleoplasm] (R-HSA-9817277)	0.556	3

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