p-AGTRAP-BRAF fusion [cytosol]

Stable Identifier
R-HSA-6802511
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
20526349 Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

Palanisamy, N, Ateeq, B, Kalyana-Sundaram, S, Pflueger, D, Ramnarayanan, K, Shankar, S, Han, B, Cao, Q, Cao, X, Suleman, K, Kumar-Sinha, C, Dhanasekaran, SM, Chen, YB, Esgueva, R, Banerjee, S, Lafargue, CJ, Siddiqui, J, Demichelis, F, Moeller, P, Bismar, TA, Kuefer, R, Fullen, DR, Johnson, TM, Greenson, JK, Giordano, TJ, Tan, P, Tomlins, SA, Varambally, S, Rubin, MA, Maher, CA, Chinnaiyan, AM

Nat. Med. 2010
External Reference Information
External Reference
UniProt:Q6RW13 AGTRAP
Gene Names
AGTRAP, ATRAP
Chain
chain:1-159
Reference Genes
BioGPS Gene:57085 AGTRAP
COSMIC (genes):AGTRAP AGTRAP
CTD Gene:57085 AGTRAP
dbSNP Gene:57085 AGTRAP
ENSEMBL:ENSG00000177674 AGTRAP
HGNC:13539 AGTRAP
KEGG Gene (Homo sapiens):57085 AGTRAP
Monarch:57085 AGTRAP
NCBI Gene:57085 AGTRAP
OMIM:608729 AGTRAP
UCSC:Q6RW13 AGTRAP
Reference Transcript
Other Identifiers
0001170053
11727478_a_at
11753685_a_at
11753686_s_at
11753687_x_at
1555736_a_at
16659054
225059_at
2320412
2320413
2320417
2320420
2320421
2320423
2320424
2320425
44120
56548_at
57085
7897745
AAF89547
AAH17328
AAL26806
AAR25556
AF165187
AF312374
AGTRAP
AGTRAP-201
AGTRAP-203
AGTRAP-204
AGTRAP-205
AGTRAP-206
AL953897
AY488088
BC017328
BE782705
CA866314
CCDS136
CCDS30585
CCDS30586
CCDS41248
CCDS44056
CH471130
D6RB40
D6RBK6
EAW71702
ENSG00000177674
ENSP00000319713
ENSP00000365816
ENSP00000365824
ENSP00000383688
ENSP00000408505
ENST00000314340
ENST00000314340.9
ENST00000376629
ENST00000376629.8
ENST00000376637
ENST00000376637.7
ENST00000400895
ENST00000400895.6
ENST00000452018
ENST00000452018.6
EntrezGene:57085
EntrezGene:AGTRAP
GE62121
GE82526
GO:0000139
GO:0001666
GO:0003013
GO:0003674
GO:0004945
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0005886
GO:0005938
GO:0006950
GO:0007165
GO:0008150
GO:0008217
GO:0016020
GO:0016021
GO:0030659
GO:0031410
GO:0038166
GO:0043226
GO:0043231
HGNC:13539
HPA044120
Hs.12854.0.S2_3p_at
Hs2.12854.2.S1_3p_s_at
ILMN_1802458
ILMN_2307656
IPR009436
MIM:608729
NM_001040194
NM_001040195
NM_001040196
NM_001040197
NM_020350
NP_001035284
NP_001035285
NP_001035286
NP_001035287
NP_065083
PF06396
PH_hs_0001230
SM00805
TC01000147.hg
UPI000006F3FB
UPI00001574DC
UPI000047036F
UPI0000D6596E
UPI0000D6596F
X6R9H3
XM_011541799
XM_011541800
XM_011541802
XP_011540101
XP_011540102
XP_011540104
Participant Of
hasComponent
Other forms of this molecule
AGTRAP-BRAF fusion [cytosol]
Modified Residues
Name
Insertion of residues 288 to 545 at 160 from UniProt:P15056 BRAF
Coordinate
160
Name
O-phospho-L-serine at 445
Coordinate
445
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 599
Coordinate
599
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 602
Coordinate
602
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
gastric adenocarcinoma 3717 adenocarcinoma of stomach (disorder), stomach adenocarcinoma
Cross References
RefSeq
OpenTargets
GeneCards
PRO
HMDB Protein
Interactors (15)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96CM8 ACSF2  1 0.666 4
 UniProt:Q96PE7 MCEE  1 0.666 4
 UniProt:P53365 ARFIP2  1 0.666 4
 UniProt:Q8IWL3 HSCB  5 0.666 4
 UniProt:Q05329 GAD2  2 0.556 3
 UniProt:O95363 FARS2  1 0.556 3
 UniProt:P49590 HARS2  1 0.556 3
 UniProt:Q00059 TFAM  2 0.556 3
 UniProt:Q99757 TXN2  3 0.556 3
 UniProt:Q6IN84 MRM1  1 0.556 3
 UniProt:P09429 HMGB1  5 0.556 3
 UniProt:Q96E29 MTERF3  2 0.556 3
 UniProt:Q99259 GAD1  2 0.556 3
 UniProt:O95971 CD160  1 0.556 3
 UniProt:Q9UKL6 PCTP  1 0.556 3