DDB1 [nucleoplasm]

Stable Identifier
R-HSA-53489
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DDB1, DNA damage binding protein 1, DNA damage binding protein 1, Damage-specific DNA binding protein 1, DDB p127 subunit, DDBa, UV-damaged DNA-binding protein 1, UV-DDB 1, Xeroderma pigmentosum group E complementing protein, XPCe, X- associated protein 1, XAP-1
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
10585395 Cullin 4A associates with the UV-damaged DNA-binding protein DDB

Nag, A, Shiyanov, P, Raychaudhuri, P

J. Biol. Chem. 1999
External Reference Information
External Reference
UniProt:Q16531 DDB1
Gene Names
DDB1, XAP1
Chain
initiator methionine:, chain:2-1140
Reference Genes
BioGPS Gene:1642 DDB1
COSMIC (genes):DDB1 DDB1
CTD Gene:1642 DDB1
dbSNP Gene:1642 DDB1
ENSEMBL:ENSG00000167986 DDB1
HGNC:2717 DDB1
KEGG:hsa:1642 DDB1
Monarch:1642 DDB1
NCBI Gene:1642 DDB1
OMIM:600045 DDB1
UCSC:Q16531 DDB1
Reference Transcript
Other Identifiers
11715416_s_at
11748413_s_at
11751448_a_at
11762174_at
1641_s_at
1642
16738963
208619_PM_at
208619_at
3375246
3375247
3375248
3375249
3375250
3375251
3375252
3375253
3375254
3375255
3375256
3375257
3375258
3375259
3375260
3375261
3375262
3375263
3375264
3375265
3375266
3375267
3375268
3375269
3375270
3375271
3375272
3375273
3375274
3375275
3375276
3375277
3375279
3375280
3375281
3375282
3375283
3375284
3375285
3375286
3375287
3375288
3375289
3375290
3375291
3375292
3375293
3375294
3375295
3375296
3375297
3375298
3375299
3375300
7948534
A_23_P258246
A_33_P3259878
GE59088
GE84481
GO:0000781
GO:0003676
GO:0003677
GO:0003684
GO:0005515
GO:0005615
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0006281
GO:0006289
GO:0006325
GO:0006511
GO:0006915
GO:0006974
GO:0007010
GO:0007056
GO:0010498
GO:0012501
GO:0016055
GO:0016567
GO:0019076
GO:0022414
GO:0030163
GO:0030674
GO:0031464
GO:0031465
GO:0032991
GO:0034644
GO:0035234
GO:0035861
GO:0042752
GO:0043066
GO:0043161
GO:0043226
GO:0044725
GO:0044877
GO:0045070
GO:0045722
GO:0045732
GO:0046726
GO:0048511
GO:0051093
GO:0051702
GO:0060090
GO:0070062
GO:0070914
GO:0071987
GO:0080008
GO:0097602
GO:0160072
GO:1901990
GO:2000242
HMNXSV003049600
HMNXSV003052155
ILMN_1695430
ILMN_1748105
ILMN_1754219
ILMN_1774735
ILMN_1775937
PH_hs_0023527
TC11001851.hg
U32986_s_at
g695361_3p_at
Participates
as a component of
Inferred To
ddb1 [nucleoplasm] (Danio rerio)
ddb1 [nucleoplasm] (Schizosaccharomyces pombe)
ddb1 [nucleoplasm] (Xenopus tropicalis)
ddb-1 [nucleoplasm] (Caenorhabditis elegans)
Ddb1 [nucleoplasm] (Mus musculus)
Ddb1 [nucleoplasm] (Rattus norvegicus)
pic [nucleoplasm] (Drosophila melanogaster)
Ghost homologue of DDB1 [nucleoplasm] (Saccharomyces cerevisiae)
DDB1 [nucleoplasm] (Bos taurus)
DDB1 [nucleoplasm] (Canis familiaris)
DDB1 [nucleoplasm] (Gallus gallus)
DDB1 [nucleoplasm] (Plasmodium falciparum)
DDB1 [nucleoplasm] (Sus scrofa)
repE [nucleoplasm] (Dictyostelium discoideum)
Cross References
OpenTargets
ENSEMBL
HPA
GeneCards
PRO
Pharos - Targets
GlyGen
HMDB Protein
PDB
7UKN, 9BBE, 7OOP, 8BUL, 8BUT, 4A0B, 8BUP, 7V7C, 7U8F, 8D7Y, 3I89, 3I7O, 8D7X, 6R8Y, 6H0G, 8BU5, 3I8C, 8TNQ, 8BU4, 8BUE, 7LPS, 8BUI, 2B5M, 6FCV, 6Q0V, 8ROX, 5HXB, 5V3O, 6SJ7, 8ROY, 6BNB, 4TZ4, 6BN9, 8U16, 3I7L, 6UML, 7OO3, 9BBI, 8BUK, 4A11, 4A08, 3I7K, 8BUS, 8BUO, 3EI4, 8D81, 8G66, 2B5L, 8UH6, 3I7H, 8AJN, 8BU3, 6DSZ, 6TD3, 8BUD, 8BU7, 3EI1, 6Q0R, 8BUB, 8BUH, 8WQR, 7OKQ, 8CVP, 4CI2, 5FQD, 6Q0W, 2HYE, 8TL6, 6BOY, 6UD7, 8U17, 6BN8, 6ZX9, 4E54, 9BBG, 8D80, 8BUN, 4A09, 8OV6, 6XK9, 8AJO, 7V7B, 8BUR, 8D7Z, 8TNP, 6R91, 8OJH, 7ZNN, 8B3I, 8TNR, 3I7N, 4A0L, 9FMR, 8BUC, 8BU2, 8BUA, 8BU9, 6H0F, 8BUG, 3EI2, 8OIZ, 4E5Z, 8D7U, 5JK7, 4CI3, 6ZUE, 7OPC, 3I7P, 8B3F, 7OPD, 9BBH, 8B3D, 4A0A, 8BUM, 8B3G, 8AJM, 8BUQ, 8D7W, 6R92, 3E0C, 7OOB, 6R8Z, 7ZN7, 6UE5, 8QH5, 8BU6, 8BU1, 8BUF, 8G46, 3EI3, 3I8E, 8T9A, 8BUJ, 2B5N, 8D7V, 6R90, 6PAI, 4CI1, 4A0K, 8DEY, 8U15, 8TZX, 6BN7
Interactors (15)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q92466 DDB2  3 0.967 23
 UniProt:Q96SW2 CRBN  1 0.723 4
 UniProt:Q15843 NEDD8  8 0.643 5
 UniProt:Q13418 ILK  1 0.564 2
 UniProt:O75530 EED  1 0.564 4
 UniProt:P62877 RBX1  2 0.527 3
 UniProt:Q5S007 LRRK2  1 0.527 3
 UniProt:Q9C0C7 AMBRA1  2 0.527 2
 UniProt:Q8NHY2 RFWD2  3 0.527 2
 UniProt:P10636-8 MAPT  3 0.527 5
 UniProt:P42858 HTT  1 0.527 2
 UniProt:P42224 STAT1  8 0.508 2
 UniProt:Q15022 SUZ12  2 0.462 10
 UniProt:Q15910 EZH2  1 0.462 10
 UniProt:Q9NX09 DDIT4  1 0.462 2
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