Reactome | ddb-1 [nucleoplasm]

ddb-1 [nucleoplasm]

Stable Identifier

R-CEL-53489

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

DDB1, Q21554

Locations in the PathwayBrowser

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DNA Repair (Caenorhabditis elegans)

- DNA Damage Bypass (Caenorhabditis elegans)
  - Recognition of DNA damage by PCNA-containing replication complex (Caenorhabditis elegans)
    - RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Caenorhabditis elegans)
      - RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Caenorhabditis elegans)
        
        RBX1:CUL4:DDB1:DTL [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - RBX1:CUL4:DDB1:DTL [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
    - RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Caenorhabditis elegans)
      - RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Caenorhabditis elegans)
        
        RBX1:CUL4:DDB1:DTL [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - RBX1:CUL4:DDB1:DTL [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
- Nucleotide Excision Repair (Caenorhabditis elegans)
  - Global Genome Nucleotide Excision Repair (GG-NER) (Caenorhabditis elegans)
    - DNA Damage Recognition in GG-NER (Caenorhabditis elegans)
      - PARP1 or PARP2 PARylates DDB2 and autoPARylates (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:PAR-DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - UV-DDB ubiquitinates XPC (Caenorhabditis elegans)
        
        UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site (Caenorhabditis elegans)
        
        UV-DDB:COP9 Signalosome [nucleoplasm] (Caenorhabditis elegans)
        
        UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
    - Dual Incision in GG-NER (Caenorhabditis elegans)
      - 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Caenorhabditis elegans)
        
        GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Caenorhabditis elegans)
        
        PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:PAR-DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Caenorhabditis elegans)
        
        GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Caenorhabditis elegans)
        
        Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Caenorhabditis elegans)
        
        PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:PAR-DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - DNA polymerases delta, epsilon or kappa bind the GG-NER site (Caenorhabditis elegans)
        
        GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Caenorhabditis elegans)
        
        PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:PAR-DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Caenorhabditis elegans)
        
        PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:PAR-DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
    - Formation of Incision Complex in GG-NER (Caenorhabditis elegans)
      - ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:PAR-DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:PAR-DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - SUMOylation of XPC (Caenorhabditis elegans)
        
        Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Caenorhabditis elegans)
        
        PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:PAR-DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:PAR-DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - TFIIH binds GG-NER site to form a verification complex (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:PAR-DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        DDB1:PAR-DDB2 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
  - Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Caenorhabditis elegans)
    - Dual incision in TC-NER (Caenorhabditis elegans)
      - 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Caenorhabditis elegans)
        
        TC-NER incision complex [nucleoplasm] (Caenorhabditis elegans)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Caenorhabditis elegans)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Caenorhabditis elegans)
        
        TC-NER incision complex [nucleoplasm] (Caenorhabditis elegans)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Caenorhabditis elegans)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Caenorhabditis elegans)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - DNA polymerases delta, epsilon or kappa bind the TC-NER site (Caenorhabditis elegans)
        
        TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - ERCC2-facilitated RNA Pol II backtracking in TC-NER (Caenorhabditis elegans)
        
        TC-NER pre-incision complex [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - ERCC3-facilitated RNA Pol II backtracking in TC-NER (Caenorhabditis elegans)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
    - Formation of TC-NER Pre-Incision Complex (Caenorhabditis elegans)
      - Assembly of the pre-incision complex in TC-NER (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - ERCC8 (CSA) binds stalled RNA Pol II (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1:COP9 Signalosome [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - UVSSA:USP7 deubiquitinates ERCC6 (Caenorhabditis elegans)
        
        TC-NER pre-incision complex [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Caenorhabditis elegans)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
    - Gap-filling DNA repair synthesis and ligation in TC-NER (Caenorhabditis elegans)
      - Ligation of newly synthesized repair patch to incised DNA in TC-NER (Caenorhabditis elegans)
        
        TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
      - Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Caenorhabditis elegans)
        
        TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)
        
        TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Caenorhabditis elegans)
        
        ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Caenorhabditis elegans)
        
        ddb-1 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q21554

Gene Names

ddb-1

Reference Genes

BioGPS Gene:178156 ddb-1

CTD Gene:178156 ddb-1

ENSEMBL:WBGene00010890

KEGG Gene (Caenorhabditis elegans):CELE_M18.5 ddb-1

Monarch:178156 ddb-1

NCBI Gene:178156 ddb-1

UCSC:Q21554 ddb-1

Wormbase:WBGene00010890

Reference Transcript

RefSeq:NM_069898.7 ddb-1

Other Identifiers

173732_s_at

178156

18554830

A_12_P106738

CE23880

CE_WBGene00010890_A

CGZ0030222

GO:0003676

GO:0005515

GO:0005634

GO:0043226

M18.5

M18.5_2901-2960_0.916_7_C

M18.5_3001-3060_0.929_4_A

M18.5_3379-3438_0.924_5_B

M18_5P02281

M18_5P02382

M18_5P02819

WBGene00010890

cea2.p.96269

Participates

as a component of

Inferred From

DDB1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_502299.1

PRO

Q21554

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q86S68	1	cdt-1 [nucleoplasm] (R-CEL-68536)	0.591	3

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